Cosmo Bio USA provides a comprehensive range of extracellular matrix biology products to support research into the molecular and structural foundations of tissue organization. The portfolio includes antibodies, ELISA kits, and recombinant proteins for a wide spectrum of collagens, covering those responsible for tensile strength in bone and skin, structural support in cartilage, and integrity of basement membranes. Additional reagents for elastin and fibrillin allow detailed study of elastic fiber biology, while fibronectin and laminin products enable analysis of adhesion, migration, and polarity within cell–matrix interactions. Products targeting hyaluronan and its associated binding proteins further extend this coverage, offering tools to study hydration, viscoelasticity, and matrix signaling in diverse tissues. Together, these resources enable researchers to examine how extracellular matrix components function both as mechanical scaffolds and as regulators of cellular communication, informing studies of development, wound repair, fibrosis, and cancer biology.
Beyond structural proteins and glycosaminoglycans, the portfolio provides a robust suite of products for the enzymes and regulators that remodel the extracellular matrix. Antibodies, ELISAs, and recombinant proteins for matrix metalloproteinases—including MMP1, MMP8, and MMP13—alongside their inhibitors and cleavage products, support detailed investigation of collagen turnover, matrix degradation, and repair processes. These tools are complemented by assays for bioactive fragments such as endostatin, allowing researchers to explore the signaling roles of matrix breakdown products in angiogenesis, immune infiltration, and metastasis. By addressing both the stable structural framework and the dynamic remodeling machinery, Cosmo Bio USA delivers a comprehensive ECM biology toolkit, combining rigorously validated antibodies, quantitative ELISA systems, and recombinant standards. These resources empower scientists to dissect the balance between matrix integrity and plasticity, accelerating advances in regenerative medicine, musculoskeletal biology, oncology, and chronic disease research.
Browse the ECM biology reagent portfolio below.
