Glucose Cellular Uptake Measurement Kit (Broad Range, Fluorometric)

Cosmo Bio

Catalog No.: CSR-MBR-PMG-K01

Product Description

A complete reagent set to measure 2DG in cells after cell lysis by sonication. Insulin is a hormone that lowers the blood glucose level and is known to help glucose enter cells through an effect that enhances the activity of glucose transport, primarily in insulin-sensitive cells, such as adipocytes and skeletalmuscles.

The effect of insulin and other growth factors on cells is often assessed in the laboratory by measuring glucose uptake activity. Typically, glucose uptake is measured using 3-O-Methyl-D-Glucose or 2-deoxyglucose (2DG) labeled with radioactive 3H or other isotopes. However, the use of radioactive isotopes is not available to all labs and is subject to many restrictions. This assay kit was developed to provide a simple, rapid and convenient means to measure cellular glucose uptakewithout the use of radioisotope.

Citations for Glucose Cellular Uptake Measurement Kit (Broad Range, Fluorometric) – 9 Found

Aoi, Wataru; Hirano, Nariyuki; Lassiter, David G; Björnholm, Marie; Chibalin, Alexander V; Sakuma, Kunihiro; Tanimura, Yuko; Mizushima, Katsura; Takagi, Tomohisa; Naito, Yuji; Zierath, Juleen R; Krook, Anna. Secreted protein acidic and rich in cysteine (SPARC) improves glucose tolerance via AMP-activated protein kinase activation. Faseb Journal : Official Publication Of The Federation Of American Societies For Experimental Biology. 2019;33(9):10551-10562. 

Tsugumasa Toma et.,al.. An ADAM17 selective inhibitor promotes glucose uptake by activating AMPK. Journal of Pharmacological Sciences. 2024;154:37-46. 

Fumitaka Kawakami et., al.. LRRK2 negatively regulates glucose tolerance via regulation of membrane translocation of GLUT4 in adipocytes. FEBS Open Bio . 2023;13:2200–2214. 

Abdullah Al Mamun et., al.. Hypoxia induces the translocation of glucose transporter 1 to the plasma membrane in vascular endothelial cells. J Physiol Sci . 2020;70(44) 

Fumitaka Kawakami et., al.. Leucine-rich repeat kinase 2 negatively regulates glucose tolerance via regulation of membrane translocation of Glucose transporter type 4 in adipocytes. Research Square. 2002; 

Motoki Imai et., al.. LRRK2 Inhibition Ameliorates Dexamethasone-Induced Glucose Intolerance via Prevents Impairment in GLUT4 Membrane Translocation in Adipocytes. Biol. Pharm. Bull.. 2020;43:1660–1668. 

Yoko Tabe et., al. . Inhibition of FAO in AML co-cultured with BM adipocytes: mechanisms of survival and chemosensitization to cytarabine. Scientific Reports. 2018;8(16837) 

Takashi Hatanaka et., al.. Inhibition of SGLT2 alleviates diabetic nephropathy by suppressing high glucose-induced oxidative stress in type 1 diabetic mice. Pharmacology Research and Perspectives . 2016;4:e00239. 

Oster, H. Letter: Sputum cultures. The Medical Journal Of Australia. 1974;1(11):413.