Anti WD Repeat Domain Phosphoinositide-Interacting Protein 3 (WIPI-3/WDR45L) pAb (Mouse, Antiserum)

Cosmo Bio

SKU:
CAC-ICA-TG3-MSP1
  • Figure 1. Immunohistochemistry.

Hela cells ICAFectin441-transfected with a plasmid encoding mouse WDR45L were fixed, permeabilized and stained with rat anti-human ITIH4 serum (diluted 1/100) and Alexa488 goat anti mouse IgG secondary antibody. Nuclei were counterstained with DAPI.
  • Figure 2. ELISA.Lysates of HeLa cells untransfected and ICAFectin441-transfected with a plasmid encoding mouse WDR45L were coated in 96 wells plate. Wells were stained with mouse anti-mouse WDR45L serum and HRP goat anti rat IgG secondary antibody.
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WDR45L is a ubiquitously expressed WD40 repeat protein upregulated in a variety of tumor tissues including ovarian and uterine cancers. WDR45L, also known as WIPI-3, comprises seven 40 amino acid (WD40) repeats. WD40 repeats are found in many eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in multiple functions, including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. This protein regulates cell cycle transcription and signal transduction, and it is believed to be involved in cell death by apoptosis and autophagy. In recent years, it has also been used as a marker for neurodegenerative diseases associated with cell death.



Product Specifications
Application ELISA, IHC, IF
Reactivity Mouse
Clonality Polyclonal
Host Mouse


Documents & Links for Anti WD Repeat Domain Phosphoinositide-Interacting Protein 3 (WIPI-3/WDR45L) pAb (Mouse, Antiserum)
Datasheet cac-ica-tg3-msp1_anti-wdr45l-pab_datasheet.pdf

Documents & Links for Anti WD Repeat Domain Phosphoinositide-Interacting Protein 3 (WIPI-3/WDR45L) pAb (Mouse, Antiserum)
Datasheet cac-ica-tg3-msp1_anti-wdr45l-pab_datasheet.pdf