Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]

Catalog No:
CAC-TIP-PTD-P07
$679.00

Format: Ammonium sulfate precipitated serum (Ig fraction) in 50% glycerol with azide preservative. Prepared from fresh rabbits immunized with a peptide identical to the very popular, but sold out, CAC-TIP-PTD-PO1 that was sold as diluted serum.

Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.

Application: WB, IHC, ELISA 
Clonality: Polyclonal 
Host: Rabbit 
Purification: Ammonium Sulfate 
Reactivity: Human 

TDP-43, a heterogeneous nuclear ribonucleoprotein, was identified as a component of ubiquitin-positive and tau-negative inclusions observed in cases of frontotemporal lobar degeneration (FTLD-U) and amyotrophic lateral sclerosis (ALS). Immunochemical analyses using antibodies generated against phospho- and non-phosphopeptides of human TDP-43 revealed that abnormally phosphorylated full-length TDP-43 (45 kDa), C-terminal fragments (~25 kDa) and smearing substances are deposited as intracellular inclusions in affected regions of FTLD-U and ALS cases.

These antibodies are powerful tools for biochemical and immunohistochemical analyses of neurodegenerative diseases and for evaluation of cellular or animal models of TDP-43 proteinopathy.

Documents & Links for Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]
Datasheet Anti phospho TDP-43 (pS409/410) pAb Datasheet
Vendor Page Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01] at Cosmo Bio LTD

Documents & Links for Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]
Datasheet Anti phospho TDP-43 (pS409/410) pAb Datasheet
Vendor Page Anti phospho TDP-43 (pS409/410) pAb [replaces CAC-TIP-PTD-P01]