Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7)

Cosmo Bio

SKU:
CAC-CEC-001
  • Reactivity of histone H3 S10ph antibody 6G8B7 against histone H3 peptides.
  • Immunoblot analysis of HeLa cell extracts using histone H3 S10ph antibody 6G8B7.
  • Immunocytochemical analysis of HeLa Cell using histone H3 S10ph antibody 6G8B7.
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$638.00
Formerly Cat. No.: CAC-CE-034A
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Background
Post-translation modifications of histones modulate the accessibility and transcriptional competence of specific chromatin regions within the eukaryotic genome. Phosphorylation of histone H3 is unique in the sense that it associates on one hand with open chromatin during gene activation and marks on the other hand highly condensed chromatin during mitosis.

Application
・ Western blotting: 1/2500
・ Immunocytochemistry: 1/5000

Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.

The composition of Histone H3 peptides and the reactivity of Histone H3 S10ph antibody, 6G8B7.

H3 peptide               1   ARTKQTARKS   TGGKAPRKQ      19
H3 S10ph peptide   1   ARTKQTARKSphTGGKAPRKQ      19
H3 S28ph peptide     21      ATKAARKSphAPATGGVKKPH   39

References
1) Strahl and Allis, (2000) Nature. 403(6765):41-5. PMID: 10638745



Product Specifications
Application ICC, WB, ELISA
Reactivity Monkey, Mouse, Rat, Human, Hamster
Clonality Monoclonal (Clone No.: 6G8B7)
Host Rat


Documents & Links for Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7)
Datasheet Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7) Datasheet

Documents & Links for Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7)
Datasheet Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7) Datasheet