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Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.
Application: ICC, WB, ELISAClonality: Monoclonal
Host: Rat
Purification: Ion-exchange Chromatography
Reactivity: Monkey, Mouse, Rat, Human, Hamster
Background
Post-translation modifications of histones modulate the accessibility and transcriptional competence of specific chromatin regions within the eukaryotic genome. Phosphorylation of histone H3 is unique in the sense that it associates on one hand with open chromatin during gene activation and marks on the other hand highly condensed chromatin during mitosis.
Application
ã» Western blotting: 1/2500
ã» Immunocytochemistry: 1/5000
Other applications have not been tested.
Optimal dilutions/concentrations should be determined by the end user.
The composition of Histone H3 peptides and the reactivity of Histone H3 S10ph antibody, 6G8B7.
H3 peptide 1 ARTKQTARKS TGGKAPRKQ 19
H3 S10ph peptideããã1 ARTKQTARKSphTGGKAPRKQ 19
H3 S28ph peptide 21 ATKAARKSphAPATGGVKKPH 39
References
1) Strahl and Allis, (2000) Nature. 403(6765):41-5. PMID: 10638745
| Documents & Links for Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7) | |
| Datasheet | Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7) Datasheet |
| Documents & Links for Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7) | |
| Datasheet | Anti Histone H3.1 (HIST1H3A) S10ph mAb (Clone 6G8B7) Datasheet |
