Anti CNP mAb (Clone CL2887, ATL-AMAb91072)

Atlas Antibodies

SKU:
ATL-AMAb91072-25
  • Immunohistochemical staining of human cerebral cortex shows strong immunoreactivity in oligodendrocytes.
  • Immunofluorescence staining of RH-30 cells using the Anti-CNP monoclonal antibody, showing specific staining in the cytosol in green. Microtubule- and nuclear probes are visualized in red and blue, respectively (where available).
  • Lane 1: Marker [kDa] 250, 130, 100, 70, 55, 35, 25, 15, 10<br/>Lane 2: Human Cerebral Cortex tissue
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Protein Description: 2',3'-cyclic nucleotide 3' phosphodiesterase
Gene Name: CNP
Alternative Gene Name:
Clone ID: CL2887
Isotype: IgG2b
Interspecies mouse/rat: ENSMUSG00000006782: 76%, ENSRNOG00000017496: 77%
Entrez Gene ID: 1267
Uniprot ID: P09543
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, ICC, IHC
Reactivity Human, Mouse, Rat
Clonality Monoclonal IgG2b (Clone No.: CL2887)
Host Mouse
Gene ID - Mouse ENSMUSG00000006782
Gene ID - Rat ENSRNOG00000017496
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti CNP mAb (Clone CL2887, ATL-AMAb91072)
Datasheet Anti CNP mAb (Clone CL2887, ATL-AMAb91072) Datasheet (External Link)
Vendor Page Anti CNP mAb (Clone CL2887, ATL-AMAb91072) at Atlas Antibodies

Documents & Links for Anti CNP mAb (Clone CL2887, ATL-AMAb91072)
Datasheet Anti CNP mAb (Clone CL2887, ATL-AMAb91072) Datasheet (External Link)
Vendor Page Anti CNP mAb (Clone CL2887, ATL-AMAb91072)



Citations for Anti CNP mAb (Clone CL2887, ATL-AMAb91072) – 9 Found
Swire, Matthew; Assinck, Peggy; McNaughton, Peter A; Lyons, David A; Ffrench-Constant, Charles; Livesey, Matthew R. Oligodendrocyte HCN2 Channels Regulate Myelin Sheath Length. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2021;41(38):7954-7964.  PubMed
Sadler, Gemma L; Lewis, Katherine N; Narayana, Vinod K; De Souza, David P; Mason, Joel; McLean, Catriona; Gonsalvez, David G; Turner, Bradley J; Barton, Samantha K. Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis. Metabolites. 2022;12(6)  PubMed
Milbreta, Ulla; Lin, Junquan; Pinese, Coline; Ong, William; Chin, Jiah Shin; Shirahama, Hitomi; Mi, Ruifa; Williams, Anna; Bechler, Marie E; Wang, Jun; Ffrench-Constant, Charles; Hoke, Ahmet; Chew, Sing Yian. Scaffold-Mediated Sustained, Non-viral Delivery of miR-219/miR-338 Promotes CNS Remyelination. Molecular Therapy : The Journal Of The American Society Of Gene Therapy. 2019;27(2):411-423.  PubMed
Swire, Matthew; Kotelevtsev, Yuri; Webb, David J; Lyons, David A; Ffrench-Constant, Charles. Endothelin signalling mediates experience-dependent myelination in the CNS. Elife. 2019;8( 31657718)  PubMed
James, Owen G; Selvaraj, Bhuvaneish T; Magnani, Dario; Burr, Karen; Connick, Peter; Barton, Samantha K; Vasistha, Navneet A; Hampton, David W; Story, David; Smigiel, Robert; Ploski, Rafal; Brophy, Peter J; Ffrench-Constant, Charles; Lyons, David A; Chandran, Siddharthan. iPSC-derived myelinoids to study myelin biology of humans. Developmental Cell. 2021;56(9):1346-1358.e6.  PubMed
Swire, Matthew; Ffrench-Constant, Charles. Staining and Quantitative Analysis of Myelinating Oligodendrocytes in the Mouse Grey Matter. Bio-Protocol. 2020;10(20):e3792.  PubMed
Neely, Sarah A; Williamson, Jill M; Klingseisen, Anna; Zoupi, Lida; Early, Jason J; Williams, Anna; Lyons, David A. New oligodendrocytes exhibit more abundant and accurate myelin regeneration than those that survive demyelination. Nature Neuroscience. 2022;25(4):415-420.  PubMed
Barton, Samantha K; Magnani, Dario; James, Owen G; Livesey, Matthew R; Selvaraj, Bhuvaneish T; James, Owain T; Perkins, Emma M; Gregory, Jenna M; Cleary, Elaine; Ausems, C Rosanne M; Carter, Roderick N Carter; Vasistha, Navneet A; Zhao, Chen; Burr, Karen; Story, David; Cardinali, Alessandra; Morton, Nicholas M; Hardingham, Giles E; Wyllie, David J A; Chandran, Siddharthan. Transactive response DNA-binding protein-43 proteinopathy in oligodendrocytes revealed using an induced pluripotent stem cell model. Brain Communications. 3(4):fcab255.  PubMed
McNamara, Niamh B; Munro, David A D; Bestard-Cuche, Nadine; Uyeda, Akiko; Bogie, Jeroen F J; Hoffmann, Alana; Holloway, Rebecca K; Molina-Gonzalez, Irene; Askew, Katharine E; Mitchell, Stephen; Mungall, William; Dodds, Michael; Dittmayer, Carsten; Moss, Jonathan; Rose, Jamie; Szymkowiak, Stefan; Amann, Lukas; McColl, Barry W; Prinz, Marco; Spires-Jones, Tara L; Stenzel, Werner; Horsburgh, Karen; Hendriks, Jerome J A; Pridans, Clare; Muramatsu, Rieko; Williams, Anna; Priller, Josef; Miron, Veronique E. Microglia regulate central nervous system myelin growth and integrity. Nature. 2023;613(7942):120-129.  PubMed