Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum)

Cosmo Bio LTD

Catalog No: CAC-SK-T01-003

Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.

Application: WB, IHC, IP 
Clonality: Polyclonal 
Host: Rabbit 
Purification: Serum 
Reactivity: Human, Mouse 

Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal tails of core histones (H2A, H2B, H3 and H4). Histone deacetylation is a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5'-YTGAT-3' sites. It is also involved in pseudohyphal growth.

References:
Yoshida et al. (2001) Proprotein convertase PACE4 is down-regulated by the basic helix-loop-hekix transcription factor hash-1 and MASH-1. Biochem. J. 360, 683-689.

Citations for Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum) – 4 Found

Wen et al. 2019. The PROK2/PROKR2 Signaling Pathway is Required for the Migration of Most Olfactory Bulb Interneurons. J Comp Neurol. :.   , Journal

Guo et al. 2019. Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. :.   , Journal

Zhang et al. 2016. The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 16(5):1431-44.   , Journal

Zhou et al. 2015. Transcription factors COUP-TFI and COUP-TFII are required for the production of granule cells in the mouse olfactory bulb. Development. 142:1593-605.   , Journal