Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum)

Cosmo Bio

SKU: CAC-SK-T01-003

Component of the RPD3C(L) histone deacetylase complex (HDAC). Responsible for the deacetylation of lysine residues on the N-terminal tails of core histones (H2A, H2B, H3 and H4). Histone deacetylation is a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. ASH1 is necessary to repress HO in daughter cells to block mating-type switching through its binding to HO promoter 5'-YTGAT-3' sites. It is also involved in pseudohyphal growth.

References:
Yoshida et al. (2001) Proprotein convertase PACE4 is down-regulated by the basic helix-loop-hekix transcription factor hash-1 and MASH-1. Biochem. J. 360, 683-689.

Product Specifications

• Application: WB, IHC, IP
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Host: Rabbit

Citations for Anti Achaete-Scute Homolog 1 (ASH-1/MASH-1) pAb (Rabbit, Antiserum) – 4 Found

Zhang, Qiangqiang; Zhang, Yue; Wang, Chunyang; Xu, Zhejun; Liang, Qifei; An, Lei; Li, Jiwen; Liu, Zhidong; You, Yan; He, Miao; Mao, Ying; Chen, Bin; Xiong, Zhi-Qi; Rubenstein, John L; Yang, Zhengang. The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Reports. 2016;16(5):1431-1444. 

Zhou, Xing; Liu, Fang; Tian, Miao; Xu, Zhejun; Liang, Qifei; Wang, Chunyang; Li, Jiwen; Liu, Zhidong; Tang, Ke; He, Miao; Yang, Zhengang. Transcription factors COUP-TFI and COUP-TFII are required for the production of granule cells in the mouse olfactory bulb. Development (Cambridge, England). 2015;142(9):1593-605. 

Guo, Teng; Liu, Guoping; Du, Heng; Wen, Yan; Wei, Song; Li, Zhenmeiyu; Tao, Guangxu; Shang, Zicong; Song, Xiaolei; Zhang, Zhuangzhi; Xu, Zhejun; You, Yan; Chen, Bin; Rubenstein, John L; Yang, Zhengang. Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cerebral Cortex (New York, N.y. : 1991). 2019;29(11):4831-4849. 

Wen, Yan; Zhang, Zhuangzhi; Li, Zhenmeiyu; Liu, Guoping; Tao, Guangxu; Song, Xiaolei; Xu, Zhejun; Shang, Zicong; Guo, Teng; Su, Zihao; Chen, Haotian; You, Yan; Li, Jiada; Yang, Zhengang. The PROK2/PROKR2 signaling pathway is required for the migration of most olfactory bulb interneurons. The Journal Of Comparative Neurology. 2019;527(18):2931-2947.