The Vesicular Stomatitis Virus (VSV) G tag is derived from the glycoprotein of VSV, an enveloped RNA virus belonging to the Rhabdoviridae family. VSV G plays a critical role in viral assembly and budding from the plasma membrane of host cells. The commonly used VSV-G epitope tag corresponds to the sequence YTDIEMNRLGK, located in the extracellular membrane-proximal stem region of the glycoprotein, which is essential for efficient budding.
As a fusion tag, VSV-G enables convenient detection, localization, and characterization of recombinant proteins, especially when protein-specific antibodies are not available.
This monoclonal antibody specifically recognizes the VSV-G epitope and is optimized for Western blotting, providing sensitive and reliable detection of VSV-G–tagged proteins in research applications.
