
Product Description
Anti-mouse CD8 clone choice is critical when mouse MHC I tetramers, as some clones, including 53-6.7, lead to high background staining of all CD8+ T cells, rather than the antigen-specific ones. For best results, clone KT15 in FITC (MBL-K0227-4) is recommended. Additional information can be found in the datasheet that accompanies mouse class I tetramers, as well as the following reference containing a protocol for performing a cross titration series for optimization: Current Protocols in Immunology, MHC-Peptide tetramers to Visualize Antigen-Specific T Cells, Section 17.3.23-24, Supplement 55Product Specifications | |
Application | FC |
Reactivity | Mouse |
Conjugation | BV421 |
Immunogen | OVA |
Peptide Sequence | SIINFEKL |
Class | Class I |
MHC Allele | H-2Kb |
Documents & Links for H-2Kb OVA Tetramer-SIINFEKL-BV421 | |
Datasheet | H-2Kb OVA Tetramer-SIINFEKL-BV421 Datasheet |
Documents & Links for H-2Kb OVA Tetramer-SIINFEKL-BV421 | |
Datasheet | H-2Kb OVA Tetramer-SIINFEKL-BV421 Datasheet |
Citations for H-2Kb OVA Tetramer-SIINFEKL-BV421 – 1 Found |
Stark, Felicity C; Agbayani, Gerard; Sandhu, Jagdeep K; Akache, Bassel; McPherson, Charis; Deschatelets, Lise; Dudani, Renu; Hewitt, Melissa; Jia, Yimei; Krishnan, Lakshmi; McCluskie, Michael J. Simplified Admix Archaeal Glycolipid Adjuvanted Vaccine and Checkpoint Inhibitor Therapy Combination Enhances Protection from Murine Melanoma. Biomedicines. 2019;7(4) PubMed |