Product Description
Anti-mouse CD8 clone choice is critical when mouse MHC I tetramers, as some clones, including 53-6.7, lead to high background staining of all CD8+ T cells, rather than the antigen-specific ones. For best results, clone KT15 in FITC (MBL-K0227-4) is recommended. Additional information can be found in the datasheet that accompanies mouse class I tetramers, as well as the following reference containing a protocol for performing a cross titration series for optimization: Current Protocols in Immunology, MHC-Peptide tetramers to Visualize Antigen-Specific T Cells, Section 17.3.23-24, Supplement 171| Product Specifications | |
| Application | FC |
| Reactivity | Mouse |
| Conjugation | BV421 |
| Immunogen | LCMV NP369 |
| Peptide Sequence | FQPQNGQFI |
| Class | Class I |
| Sequence Location | 369-404 |
| MHC Allele | H-2Db |
| Documents & Links for Tetramer/BV421 - H-2 Db LCMV (FQPQNGQFI) | |
| Datasheet | Tetramer/BV421 - H-2 Db LCMV (FQPQNGQFI) Datasheet |
| Documents & Links for Tetramer/BV421 - H-2 Db LCMV (FQPQNGQFI) | |
| Datasheet | Tetramer/BV421 - H-2 Db LCMV (FQPQNGQFI) Datasheet |