Schwann Cell Line (IMS32), mouse

Cosmo Bio

Catalog No.: PMC-SWN-IMS32C

Product Description

Schwann Cell Line (IMS32) (mouse), for use with Schwann Cell (IMS32) Medium

Not included: Schwann Cell (IMS32) Medium, 250ml (PMC-SWN-MM)

Citations for Schwann Cell Line (IMS32), mouse – 21 Found

Watabe, K; Fukuda, T; Tanaka, J; Honda, H; Toyohara, K; Sakai, O. Spontaneously immortalized adult mouse Schwann cells secrete autocrine and paracrine growth-promoting activities. Journal Of Neuroscience Research. 1995;41(2):279-90. 

Sango, Kazunori; Suzuki, Takeshi; Yanagisawa, Hiroko; Takaku, Shizuka; Hirooka, Hiroko; Tamura, Miyuki; Watabe, Kazuhiko. High glucose-induced activation of the polyol pathway and changes of gene expression profiles in immortalized adult mouse Schwann cells IMS32. Journal Of Neurochemistry. 2006;98(2):446-58. 

Sango, Kazunori; Yanagisawa, Hiroko; Takaku, Shizuka; Kawakami, Emiko; Watabe, Kazuhiko. Immortalized adult rodent Schwann cells as in vitro models to study diabetic neuropathy. Experimental Diabetes Research. 2011:374943. 

Hao, Wu; Tashiro, Syoichi; Hasegawa, Tomoka; Sato, Yuiko; Kobayashi, Tami; Tando, Toshimi; Katsuyama, Eri; Fujie, Atsuhiro; Watanabe, Ryuichi; Morita, Mayu; Miyamoto, Kana; Morioka, Hideo; Nakamura, Masaya; Matsumoto, Morio; Amizuka, Norio; Toyama, Yoshiaki; Miyamoto, Takeshi. Hyperglycemia Promotes Schwann Cell De-differentiation and De-myelination via Sorbitol Accumulation and Igf1 Protein Down-regulation. The Journal Of Biological Chemistry. 2015;290(28):17106-15. 

Moriwaki, Yasuhiro; Ohno, Yuho; Ishii, Tomohiro; Takamura, Yuki; Kita, Yuko; Watabe, Kazuhiko; Sango, Kazunori; Tsuji, Shoutaro; Misawa, Hidemi. SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes. Plos One. 13(6):e0199829. 

Tatsumi, Yasuaki; Kato, Ayako; Sango, Kazunori; Himeno, Tatsuhito; Kondo, Masaki; Kato, Yoshiro; Kamiya, Hideki; Nakamura, Jiro; Kato, Koichi. Omega-3 polyunsaturated fatty acids exert anti-oxidant effects through the nuclear factor (erythroid-derived 2)-related factor 2 pathway in immortalized mouse Schwann cells. Journal Of Diabetes Investigation. 2019;10(3):602-612. 

Min, Se Hee; Kim, Jung Hee; Kang, Yu Mi; Lee, Seung Hak; Oh, Byung-Mo; Han, Kyou-Sup; Zhang, Meihua; Kim, Hoe Suk; Moon, Woo Kyung; Lee, Hakmo; Park, Kyong Soo; Jung, Hye Seung. Transplantation of human mobilized mononuclear cells improved diabetic neuropathy. The Journal Of Endocrinology. 2018;239(3):277-287. 

Kato, Ayako; Tatsumi, Yasuaki; Yako, Hideji; Sango, Kazunori; Himeno, Tatsuhito; Kondo, Masaki; Kato, Yoshiro; Kamiya, Hideki; Nakamura, Jiro; Kato, Koichi. Recurrent short-term hypoglycemia and hyperglycemia induce apoptosis and oxidative stress via the ER stress response in immortalized adult mouse Schwann (IMS32) cells. Neuroscience Research. 2019;147:26-32. 

Mizukami, Hiroki; Osonoi, Sho; Takaku, Shizuka; Yamagishi, Shin-Ichiro; Ogasawara, Saori; Sango, Kazunori; Chung, Sookja; Yagihashi, Soroku. Role of glucosamine in development of diabetic neuropathy independent of the aldose reductase pathway. Brain Communications. 2(2):fcaa168. 

Niimi, Naoko; Yako, Hideji; Takaku, Shizuka; Chung, Sookja K; Sango, Kazunori. Aldose Reductase and the Polyol Pathway in Schwann Cells: Old and New Problems. International Journal Of Molecular Sciences. 2021;22(3) 

Inada, Rino; Hirano, Makito; Oka, Nobuyuki; Samukawa, Makoto; Saigoh, Kazumasa; Suzuki, Hidekazu; Udaka, Fukashi; Hashiguchi, Akihiro; Takashima, Hiroshi; Hamada, Yukihiro; Nakamura, Yusaku; Kusunoki, Susumu. Phenotypic and molecular diversities of spinocerebellar ataxia type 2 in Japan. Journal Of Neurology. 2021;268(8):2933-2942. 

Yako, Hideji; Niimi, Naoko; Kato, Ayako; Takaku, Shizuka; Tatsumi, Yasuaki; Nishito, Yasumasa; Kato, Koichi; Sango, Kazunori. Role of pyruvate in maintaining cell viability and energy production under high-glucose conditions. Scientific Reports. 2021;11(1):18910. 

Shinouchi, Ryosuke; Shibata, Keita; Jono, Shiori; Hasumi, Keiji; Nobe, Koji. SMTP-44D Exerts Antioxidant and Anti-Inflammatory Effects through Its Soluble Epoxide Hydrolase Inhibitory Action in Immortalized Mouse Schwann Cells upon High Glucose Treatment. International Journal Of Molecular Sciences. 2022;23(9) 

García-Reyes, Balbina; Kuzmanov, Ivan; Schneider, Reiner; Schneiker, Bianca; Efferz, Patrik; Kalff, Jörg C; Wehner, Sven. Glial cell-derived soluble factors increase the metastatic potential of pancreatic adenocarcinoma cells and induce epithelial-to-mesenchymal transition. Journal Of Cancer Research And Clinical Oncology. 2023;149(15):14315-14327. 

Yako, Hideji; Niimi, Naoko; Takaku, Shizuka; Kato, Ayako; Kato, Koichi; Sango, Kazunori. Role of Exogenous Pyruvate in Maintaining Adenosine Triphosphate Production under High-Glucose Conditions through PARP-Dependent Glycolysis and PARP-Independent Tricarboxylic Acid Cycle. International Journal Of Molecular Sciences. 2024;25(20) 

Urano, Yasuomi; Iwagaki, Anan; Takeishi, Arisa; Uchiyama, Nazuna; Noguchi, Noriko. Downregulation of the SREBP pathways and disruption of redox status by 25-hydroxycholesterol predispose cells to ferroptosis. Free Radical Biology & Medicine. 2025;228:319-328. 

Sango, Kazunori; Yako, Hideji; Niimi, Naoko; Takaku, Shizuka. Immortalized Schwann cell lines as useful tools for pathogenesis-based therapeutic approaches to diabetic peripheral neuropathy. Frontiers In Endocrinology. 15:1531209. 

Heo, Jee-In; Kim, Mi Jeong; Kim, Daehyun; Seo, Jimin; Moon, Joon Ho; Choi, Sung Hee; Lee, Hak Jong; Oh, Tae Jung. Alpha-Tocopherol-Loaded Liposomes Reduce High Glucose Induced Oxidative Stress in Schwann Cells: A Proof of Concept Study. Diabetes & Metabolism Journal. 2025;49(3):507-512. 

Yako, Hideji; Niimi, Naoko; Takaku, Shizuka; Yamauchi, Junji; Sango, Kazunori. Epalrestat Alleviates Reactive Oxygen Species and Endoplasmic Reticulum Stress by Maintaining Glycosylation in IMS32 Schwann Cells Under Exposure to Galactosemic Conditions. International Journal Of Molecular Sciences. 2025;26(4) 

Kato, Ayako; Nihei, Wataru; Yako, Hideji; Tatsumi, Yasuaki; Himeno, Tatsuhito; Kondo, Masaki; Kato, Yoshiro; Nakamura, Jiro; Kamiya, Hideki; Sango, Kazunori; Kato, Koichi. Imeglimin improves hyperglycemia and hypoglycemia-induced cell death and mitochondrial dysfunction in immortalized adult mouse Schwann IMS32 cells. Journal Of Diabetes Investigation. 2025;16(9):1586-1596. 

Hasegawa, Hideaki; Sakamoto, Eri; Watanabe, Aruma; Yamaguchi, Natsuki; Horio, Eri; Sonoda, Jukito; Yamagishi, Miu; Miyakawa, Satomi; Murakami, Fumihiro; Katahira, Yasuhiro; Mizoguchi, Izuru; Yoshimoto, Takayuki. Therapeutic effects of conditioned medium of immortalized dental pulp stem cells from human exfoliated deciduous teeth against experimental autoimmune neuritis. Scientific Reports. 2025;15(1):38554. 

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