Rep-HepG2 Cells

Cosmo Bio

Catalog No.: PMC-REP-HEPG2C

Product Description

Human liver cells with high expression of drug-metabolizing enzymes.

Rep-HepG2 cells are derived from the HepG2 human hepatoma line, treated with a DNA methylation inhibitor to induce epigenetic changes. They are characterized by robust expression of drug-metabolizing enzymes, including CYP3A4, for both Phase I and Phase II reactions. These cells make a promising human hepatocyte model for basic and drug screening research.

These cells are easy to handle and can be used for experiments just 4-5 days after seeding the frozen cells. They also support long-term culture. Ideal for use in drug metabolism studies as an alternative to traditional HepG2 or human primary hepatocytes.

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