Native collagen, Bovine dermis, 3mg/mL

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Catalog No.:
KOU-IAC-30
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$308.00
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Background
Highly purified collagen solution (pH 3.0) for cell culture. Suitable for cell cultureware coating and preparing collagen gels. The low pH of the Acid Solutions enables long term refrigerated storage. In contrast to cell-derived soluble basement membrane preparations, Collagen Solutions are free from bioactive substances, nucreic acids, MMP, etc. allowing experimental results to be evaluated more clearly.

Applications

  • Collagen coating for cell cultureware
  • Cell culture in a collagen gel
  • Cell culture on a collagen gel

Features

  • Native collagen gelates when neutralized and placed under physiological condition.
  • Ready-to-use: atelocollagen is premixed with medium

The source of collagen is bovine dermis and therefore this product contains approximately 95% type I collagen and roughly 5% type III and type V collagen.

This product is manufactured in Japan and produced from raw materials obtained from livestock certified born and raised in Australia or New Zealand. Japan, Australia and New Zealand are all recognized by the World Health Organization as having negligible risk for Bovine Spongiform Encephalitis (BSE). Nevertheless, please consult with your country's Customs office to confirm importability.




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Citations for Native collagen, Bovine dermis, 3mg/mL – 272 Found
Lee, Michelle H; Goralczyk, Anna G; Kriszt, Rókus; Ang, Xiu Min; Badowski, Cedric; Li, Ying; Summers, Scott A; Toh, Sue-Anne; Yassin, M Shabeer; Shabbir, Asim; Sheppard, Allan; Raghunath, Michael. ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs. Scientific Reports. 2016;6( 26883894):21173.  PubMed
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Murakami, Shizuko; Ohki-Hamazaki, Hiroko; Uchiyama, Yasuo. Somatostatin affects GnRH neuronal development and migration and stimulates olfactory-related fiber fasciculation. Developmental Neurobiology. 2024;84(1):3-17.  PubMed
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Tanimizu, Naoki; Ichinohe, Norihisa; Mitaka, Toshihiro. β-adrenergic receptor agonist promotes ductular expansion during 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced chronic liver injury. Scientific Reports. 2023;13(1):7084.  PubMed
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Imashiro, Chikahiro; Azuma, Tetsuya; Itai, Shun; Kuribara, Taiki; Totani, Kiichiro; Onoe, Hiroaki; Takemura, Kenjiro. Travelling ultrasound promotes vasculogenesis of three-dimensional-monocultured human umbilical vein endothelial cells. Biotechnology And Bioengineering. 2021;118(10):3760-3769.  PubMed
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Kawasoe, Ryotaro; Shinoda, Tomoyasu; Hattori, Yuki; Nakagawa, Mami; Pham, Trung Quang; Tanaka, Yoshihiro; Sagou, Ken; Saito, Kanako; Katsuki, Satoru; Kotani, Tomomi; Sano, Akihito; Fujimori, Toshihiko; Miyata, Takaki. Two-photon microscopic observation of cell-production dynamics in the developing mammalian neocortex in utero. Development, Growth & Differentiation. 2020;62(2):118-128.  PubMed
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Kojima, Chie; Nishio, Misaki; Nakajima, Yusuke; Kawano, Takeshi; Takatsuka, Kenji; Matsumoto, Akikazu. Rapid Photoinduced Single Cell Detachment from Gold Nanoparticle-Embedded Collagen Gels with Low Denaturation Temperature. Polymers. 2020;12(1)  PubMed
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Kinoshita, Sho; Mera, Katsumi; Ichikawa, Hiroko; Shimasaki, Satoko; Nagai, Mime; Taga, Yuki; Iijima, Katsumasa; Hattori, Shunji; Fujiwara, Yukio; Shirakawa, Jun-Ichi; Nagai, Ryoji. N(ω) -(Carboxymethyl)arginine Is One of the Dominant Advanced Glycation End Products in Glycated Collagens and Mouse Tissues. Oxidative Medicine And Cellular Longevity. 2019( 31583049):9073451.  PubMed
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Morikura, Takashi; Miyata, Shogo. Effect of Mechanical Compression on Invasion Process of Malignant Melanoma Using In Vitro Three-Dimensional Cell Culture Device. Micromachines. 2019;10(10)  PubMed
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Noda, Sonoko; Kawashima, Nobuyuki; Yamamoto, Mioko; Hashimoto, Kentaro; Nara, Keisuke; Sekiya, Ichiro; Okiji, Takashi. Effect of cell culture density on dental pulp-derived mesenchymal stem cells with reference to osteogenic differentiation. Scientific Reports. 2019;9(1):5430.  PubMed
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Nagai, Nao; Ohguchi, Hiroto; Nakaki, Ryo; Matsumura, Yoshihiro; Kanki, Yasuharu; Sakai, Juro; Aburatani, Hiroyuki; Minami, Takashi. Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition. Plos Genetics. 2018;14(11):e1007826.  PubMed
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Shinoda, Tomoyasu; Nagasaka, Arata; Inoue, Yasuhiro; Higuchi, Ryo; Minami, Yoshiaki; Kato, Kagayaki; Suzuki, Makoto; Kondo, Takefumi; Kawaue, Takumi; Saito, Kanako; Ueno, Naoto; Fukazawa, Yugo; Nagayama, Masaharu; Miura, Takashi; Adachi, Taiji; Miyata, Takaki. Elasticity-based boosting of neuroepithelial nucleokinesis via indirect energy transfer from mother to daughter. Plos Biology. 2018;16(4):e2004426.  PubMed
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Ahn, Mok-Ryeon; Bae, Ji-Yeon; Jeong, Da-Hye; Takahashi, Hideaki; Uto, Yoshihiro; Maruta, Hiroshi. Both triazolyl ester of ketorolac (15K) and YM155 inhibit the embryonic angiogenesis in ovo (fertilized eggs) via their common PAK1-survivin/VEGF signaling pathway. Drug Discoveries & Therapeutics. 11(6):300-306.  PubMed
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Giménez, Alícia; Duch, Paula; Puig, Marta; Gabasa, Marta; Xaubet, Antoni; Alcaraz, Jordi. Dysregulated Collagen Homeostasis by Matrix Stiffening and TGF-β1 in Fibroblasts from Idiopathic Pulmonary Fibrosis Patients: Role of FAK/Akt. International Journal Of Molecular Sciences. 2017;18(11)  PubMed
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Lee, Michelle H; Goralczyk, Anna G; Kriszt, Rókus; Ang, Xiu Min; Badowski, Cedric; Li, Ying; Summers, Scott A; Toh, Sue-Anne; Yassin, M Shabeer; Shabbir, Asim; Sheppard, Allan; Raghunath, Michael. ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs. Scientific Reports. 2016;6( 26883894):21173.  PubMed
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Machahua, Carlos; Montes-Worboys, Ana; Llatjos, Roger; Escobar, Ignacio; Dorca, Jordi; Molina-Molina, Maria; Vicens-Zygmunt, Vanesa. Increased AGE-RAGE ratio in idiopathic pulmonary fibrosis. Respiratory Research. 2016;17(1):144.  PubMed
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Piotrowski-Daspit, Alexandra S; Tien, Joe; Nelson, Celeste M. Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2016;8(3):319-31.  PubMed
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Gomes, Angélica Maciel; Bhat, Ramray; Correia, Ana Luísa; Mott, Joni D; Ilan, Neta; Vlodavsky, Israel; Pavão, Mauro S G; Bissell, Mina. Mammary Branching Morphogenesis Requires Reciprocal Signaling by Heparanase and MMP-14. Journal Of Cellular Biochemistry. 2015;116(8):1668-79.  PubMed
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Vicens-Zygmunt, Vanesa; Estany, Susanna; Colom, Adai; Montes-Worboys, Ana; Machahua, Carlos; Sanabria, Andrea Juliana; Llatjos, Roger; Escobar, Ignacio; Manresa, Frederic; Dorca, Jordi; Navajas, Daniel; Alcaraz, Jordi; Molina-Molina, Maria. Fibroblast viability and phenotypic changes within glycated stiffened three-dimensional collagen matrices. Respiratory Research. 2015;16(1):82.  PubMed
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Piotrowski, Alexandra S; Varner, Victor D; Gjorevski, Nikolce; Nelson, Celeste M. Three-dimensional traction force microscopy of engineered epithelial tissues. Methods In Molecular Biology (Clifton, N.j.). 1189( 25245695):191-206.  PubMed
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Colom, Adai; Galgoczy, Roland; Almendros, Isaac; Xaubet, Antonio; Farré, Ramon; Alcaraz, Jordi. Oxygen diffusion and consumption in extracellular matrix gels: implications for designing three-dimensional cultures. Journal Of Biomedical Materials Research. Part A. 2014;102(8):2776-84.  PubMed
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Galgoczy, Roland; Pastor, Isabel; Colom, Adai; Giménez, Alicia; Mas, Francesc; Alcaraz, Jordi. A spectrophotometer-based diffusivity assay reveals that diffusion hindrance of small molecules in extracellular matrix gels used in 3D cultures is dominated by viscous effects. Colloids And Surfaces. B, Biointerfaces. 2014;120( 24916283):200-7.  PubMed
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Okugawa, Yoji; Hirai, Yohei. A novel three-dimensional cell culture method to analyze epidermal cell differentiation in vitro. Methods In Molecular Biology (Clifton, N.j.). 1195( 24281867):183-90.  PubMed
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Pampaloni, Francesco; Berge, Ulrich; Marmaras, Anastasios; Horvath, Peter; Kroschewski, Ruth; Stelzer, Ernst H K. Tissue-culture light sheet fluorescence microscopy (TC-LSFM) allows long-term imaging of three-dimensional cell cultures under controlled conditions. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2014;6(10):988-98.  PubMed
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Tashiro, Kanae; Shishido, Mayumi; Fujimoto, Keiko; Hirota, Yuko; Yo, Kazuyuki; Gomi, Takamasa; Tanaka, Yoshitaka. Age-related disruption of autophagy in dermal fibroblasts modulates extracellular matrix components. Biochemical And Biophysical Research Communications. 2014;443(1):167-72.  PubMed
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Correia, Ana Luísa; Mori, Hidetoshi; Chen, Emily I; Schmitt, Fernando C; Bissell, Mina J. The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90β. Genes & Development. 2013;27(7):805-17.  PubMed
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Mori, Hidetoshi; Lo, Alvin T; Inman, Jamie L; Alcaraz, Jordi; Ghajar, Cyrus M; Mott, Joni D; Nelson, Celeste M; Chen, Connie S; Zhang, Hui; Bascom, Jamie L; Seiki, Motoharu; Bissell, Mina J. Transmembrane/cytoplasmic, rather than catalytic, domains of Mmp14 signal to MAPK activation and mammary branching morphogenesis via binding to integrin β1. Development (Cambridge, England). 2013;140(2):343-52.  PubMed
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Okugawa, Yoji; Hirai, Yohei. Extracellular epimorphin modulates epidermal differentiation signals mediated by epidermal growth factor receptor. Journal Of Dermatological Science. 2013;69(3):236-42.  PubMed
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Hirokawa, Shigenari; Shimanuki, Tomomasa; Kitajima, Hiroyuki; Nishimori, Yasutomo; Shimosaka, Makoto. Knockdown of electron transfer flavoprotein β subunit reduced TGF-β-induced α-SMA mRNA expression but not COL1A1 in fibroblast-populated three-dimensional collagen gel cultures. Journal Of Dermatological Science. 2012;68(3):179-86.  PubMed
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Tien, Joe; Truslow, James G; Nelson, Celeste M. Modulation of invasive phenotype by interstitial pressure-driven convection in aggregates of human breast cancer cells. Plos One. 7(9):e45191.  PubMed
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Alcaraz, Jordi; Mori, Hidetoshi; Ghajar, Cyrus M; Brownfield, Doug; Galgoczy, Roland; Bissell, Mina J. Collective epithelial cell invasion overcomes mechanical barriers of collagenous extracellular matrix by a narrow tube-like geometry and MMP14-dependent local softening. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2011;3(12):1153-66.  PubMed
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Andersen, Kristin; Mori, Hidetoshi; Fata, Jimmie; Bascom, Jamie; Oyjord, Tove; Mælandsmo, Gunhild M; Bissell, Mina. The metastasis-promoting protein S100A4 regulates mammary branching morphogenesis. Developmental Biology. 2011;352(2):181-90.  PubMed
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Hata, Yasuaki; Nakao, Shintaro; Kohno, Ri-Ichiro; Oba, Kumiyo; Kita, Takeshi; Miura, Muneki; Sassa, Yukio; Schering, Alexander; Ishibashi, Tatsuro. Role of tumour necrosis factor-α (TNFα) in the functional properties of hyalocytes. The British Journal Of Ophthalmology. 2011;95(2):261-5.  PubMed
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Hirokawa, Shigenari; Shimanuki, Tomomasa; Kitajima, Hiroyuki; Nishimori, Yasutomo; Shimosaka, Makoto. Identification of ETFB as a candidate protein that participates in the mechanoregulation of fibroblast cell number in collagen gel culture. Journal Of Dermatological Science. 2011;64(2):119-26.  PubMed
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Kawakami, Minoru; Umeda, Masafumi; Nakagata, Naomi; Takeo, Toru; Yamamura, Ken-Ichi. Novel migrating mouse neural crest cell assay system utilizing P0-Cre/EGFP fluorescent time-lapse imaging. Bmc Developmental Biology. 2011;11( 22070366):68.  PubMed
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Lee, Kangae; Gjorevski, Nikolce; Boghaert, Eline; Radisky, Derek C; Nelson, Celeste M. Snail1, Snail2, and E47 promote mammary epithelial branching morphogenesis. The Embo Journal. 2011;30(13):2662-74.  PubMed
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Pavlovich, Amira L; Boghaert, Eline; Nelson, Celeste M. Mammary branch initiation and extension are inhibited by separate pathways downstream of TGFβ in culture. Experimental Cell Research. 2011;317(13):1872-84.  PubMed
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Gjorevski, Nikolce; Nelson, Celeste M. Endogenous patterns of mechanical stress are required for branching morphogenesis. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2010;2(9):424-34.  PubMed
- Comments: IAC 3D culture
Okugawa, Yoji; Bascom, J Jamie; Hirai, Yohei. Epimorphin-derived peptide antagonists remedy epidermal parakeratosis triggered by unsaturated fatty acid. Journal Of Dermatological Science. 2010;59(3):176-83.  PubMed
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Pampaloni, Francesco; Stelzer, Ernst H K; Leicht, Stefan; Marcello, Marco. Madin-Darby canine kidney cells are increased in aerobic glycolysis when cultured on flat and stiff collagen-coated surfaces rather than in physiological 3-D cultures. Proteomics. 2010;10(19):3394-413.  PubMed
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Pavlovich, Amira L; Manivannan, Sriram; Nelson, Celeste M. Adipose stroma induces branching morphogenesis of engineered epithelial tubules. Tissue Engineering. Part A. 2010;16(12):3719-26.  PubMed
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Kanaho, Yoh-Ichiro; Enomoto, Masahiro; Endo, Daisuke; Maehiro, Sayaka; Park, Min Kyun; Murakami, Shizuko. Neurotrophic effect of gonadotropin-releasing hormone on neurite extension and neuronal migration of embryonic gonadotropin-releasing hormone neurons in chick olfactory nerve bundle culture. Journal Of Neuroscience Research. 2009;87(10):2237-44.  PubMed
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Kawahara, Shuhei; Hata, Yasuaki; Kita, Takeshi; Arita, Ryoichi; Miura, Muneki; Nakao, Shintaro; Mochizuki, Yasutaka; Enaida, Hiroshi; Kagimoto, Tadahisa; Goto, Yoshinobu; Hafezi-Moghadam, Ali; Ishibashi, Tatsuro. Potent inhibition of cicatricial contraction in proliferative vitreoretinal diseases by statins. Diabetes. 2008;57(10):2784-93.  PubMed
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Kim-Kaneyama, Joo-ri; Wachi, Nanae; Sata, Masataka; Enomoto, Soichiro; Fukabori, Kiyoko; Koh, Keitatsu; Shibanuma, Motoko; Nose, Kiyoshi. Hic-5, an adaptor protein expressed in vascular smooth muscle cells, modulates the arterial response to injury in vivo. Biochemical And Biophysical Research Communications. 2008;376(4):682-7.  PubMed
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Kita, Takeshi; Hata, Yasuaki; Arita, Ryoichi; Kawahara, Shuhei; Miura, Muneki; Nakao, Shintaro; Mochizuki, Yasutaka; Enaida, Hiroshi; Goto, Yoshinobu; Shimokawa, Hiroaki; Hafezi-Moghadam, Ali; Ishibashi, Tatsuro. Role of TGF-beta in proliferative vitreoretinal diseases and ROCK as a therapeutic target. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2008;105(45):17504-9.  PubMed
- Comments: IAC 3D culture
Okugawa, Yoji; Hirai, Yohei. Overexpression of extracellular epimorphin leads to impaired epidermal differentiation in HaCaT keratinocytes. The Journal Of Investigative Dermatology. 2008;128(8):1884-93.  PubMed
- Comments: IAC 3D culture
Hirai, Yohei; Nelson, Celeste M; Yamazaki, Kyoko; Takebe, Kyoko; Przybylo, Jennifer; Madden, Benjamin; Radisky, Derek C. Non-classical export of epimorphin and its adhesion to alphav-integrin in regulation of epithelial morphogenesis. Journal Of Cell Science. 2007;120(Pt 12):2032-43.  PubMed
- Comments: IAC 3D culture
Kita, Takeshi; Hata, Yasuaki; Miura, Muneki; Kawahara, Shuhei; Nakao, Shintaro; Ishibashi, Tatsuro. Functional characteristics of connective tissue growth factor on vitreoretinal cells. Diabetes. 2007;56(5):1421-8.  PubMed
- Comments: IAC 3D culture
Miura, Muneki; Hata, Yasuaki; Hirayama, Kumiko; Kita, Takeshi; Noda, Yoshihiro; Fujisawa, Kimihiko; Shimokawa, Hiroaki; Ishibashi, Tatsuro. Critical role of the Rho-kinase pathway in TGF-beta2-dependent collagen gel contraction by retinal pigment epithelial cells. Experimental Eye Research. 2006;82(5):849-59.  PubMed
- Comments: IAC 3D culture
Yamanaka, Tomoyuki; Horikoshi, Yosuke; Izumi, Natsuko; Suzuki, Atsushi; Mizuno, Keiko; Ohno, Shigeo. Lgl mediates apical domain disassembly by suppressing the PAR-3-aPKC-PAR-6 complex to orient apical membrane polarity. Journal Of Cell Science. 2006;119(Pt 10):2107-18.  PubMed
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Abe, Masashi; Takahashi, Masaaki; Nagano, Akira. The effect of hyaluronic acid with different molecular weights on collagen crosslink synthesis in cultured chondrocytes embedded in collagen gels. Journal Of Biomedical Materials Research. Part A. 2005;75(2):494-9.  PubMed
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Fujita, Naoko; Nagata, Saburo. Repulsive guidance of axons of spinal sensory neurons in Xenopus laevis embryos: roles of Contactin and notochord-derived chondroitin sulfate proteoglycans. Development, Growth & Differentiation. 2005;47(7):445-56.  PubMed
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Hishikawa, Keiichi; Marumo, Takeshi; Miura, Shigeki; Nakanishi, Asato; Matsuzaki, Yumi; Shibata, Katsunori; Kohike, Hiroko; Komori, Takuya; Hayashi, Matsuhiko; Nakaki, Toshio; Nakauchi, Hiromitsu; Okano, Hideyuki; Fujita, Toshiro. Leukemia inhibitory factor induces multi-lineage differentiation of adult stem-like cells in kidney via kidney-specific cadherin 16. Biochemical And Biophysical Research Communications. 2005;328(1):288-91.  PubMed
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Kagiyama, Yuka; Gotouda, Nanaka; Sakagami, Kiyo; Yasuda, Kunio; Mochii, Makoto; Araki, Masasuke. Extraocular dorsal signal affects the developmental fate of the optic vesicle and patterns the optic neuroepithelium. Development, Growth & Differentiation. 2005;47(8):523-36.  PubMed
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Kim-Kaneyama, Joo-ri; Suzuki, Wataru; Ichikawa, Kiyoko; Ohki, Takahiro; Kohno, Yoko; Sata, Masataka; Nose, Kiyoshi; Shibanuma, Motoko. Uni-axial stretching regulates intracellular localization of Hic-5 expressed in smooth-muscle cells in vivo. Journal Of Cell Science. 2005;118(Pt 5):937-49.  PubMed
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Kino-Oka, Masahiro; Yashiki, Shino; Ota, Yuka; Mushiaki, Yuko; Sugawara, Katsura; Yamamoto, Takeyuki; Takezawa, Toshiaki; Taya, Masahito. Subculture of chondrocytes on a collagen type I-coated substrate with suppressed cellular dedifferentiation. Tissue Engineering. 2005;11(3-4):597-608.  PubMed
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Yokoo, Naoki; Saito, Tomoyuki; Uesugi, Masaaki; Kobayashi, Naomi; Xin, Ke-Qin; Okuda, Kenji; Mizukami, Hiroaki; Ozawa, Keiya; Koshino, Tomihisa. Repair of articular cartilage defect by autologous transplantation of basic fibroblast growth factor gene-transduced chondrocytes with adeno-associated virus vector. Arthritis And Rheumatism. 2005;52(1):164-70.  PubMed
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Endo, Daisuke; Kogure, Kimitaka; Hasegawa, Yoshihisa; Maku-uchi, Masatoshi; Kojima, Itaru. Activin A augments vascular endothelial growth factor activity in promoting branching tubulogenesis in hepatic sinusoidal endothelial cells. Journal Of Hepatology. 2004;40(3):399-404.  PubMed
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Hirayama, Kumiko; Hata, Yasuaki; Noda, Yoshihiro; Miura, Muneki; Yamanaka, Ichiro; Shimokawa, Hiroaki; Ishibashi, Tatsuro. The involvement of the rho-kinase pathway and its regulation in cytokine-induced collagen gel contraction by hyalocytes. Investigative Ophthalmology & Visual Science. 2004;45(11):3896-903.  PubMed
- Comments: IAC 3D culture
Fujitani, Masashi; Yamagishi, Satoru; Che, Yong Ho; Hata, Katsuhiko; Kubo, Tateki; Ino, Hidetoshi; Tohyama, Masaya; Yamashita, Toshihide. P311 accelerates nerve regeneration of the axotomized facial nerve. Journal Of Neurochemistry. 2004;91(3):737-44.  PubMed
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Minami, Takashi; Horiuchi, Keiko; Miura, Mai; Abid, Md Ruhul; Takabe, Wakako; Noguchi, Noriko; Kohro, Takahide; Ge, Xijin; Aburatani, Hiroyuki; Hamakubo, Takao; Kodama, Tatsuhiko; Aird, William C. Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. The Journal Of Biological Chemistry. 2004;279(48):50537-54.  PubMed
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Kikuchi, Hiroshi; Suzuki, Keiko; Sakai, Nobuhiro; Yamada, Shoji. Odontoblasts induced from mesenchymal cells of murine dental papillae in three-dimensional cell culture. Cell And Tissue Research. 2004;317(2):173-85.  PubMed
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Minami, Takashi; Horiuchi, Keiko; Miura, Mai; Abid, Md Ruhul; Takabe, Wakako; Noguchi, Noriko; Kohro, Takahide; Ge, Xijin; Aburatani, Hiroyuki; Hamakubo, Takao; Kodama, Tatsuhiko; Aird, William C. Vascular endothelial growth factor- and thrombin-induced termination factor, Down syndrome critical region-1, attenuates endothelial cell proliferation and angiogenesis. The Journal Of Biological Chemistry. 2004;279(48):50537-54.  PubMed
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Minami, Takashi; Murakami, Takeshi; Horiuchi, Keiko; Miura, Mai; Noguchi, Tamio; Miyazaki, Jun-ichi; Hamakubo, Takao; Aird, William C; Kodama, Tatsuhiko. Interaction between hex and GATA transcription factors in vascular endothelial cells inhibits flk-1/KDR-mediated vascular endothelial growth factor signaling. The Journal Of Biological Chemistry. 2004;279(20):20626-35.  PubMed
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Orban, Janine M; Wilson, Lorri B; Kofroth, Jessica A; El-Kurdi, Mohammed S; Maul, Timothy M; Vorp, David A. Crosslinking of collagen gels by transglutaminase. Journal Of Biomedical Materials Research. Part A. 2004;68(4):756-62.  PubMed
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Hecht, Iris; Cahalon, Liora; Hershkoviz, Rami; Lahat, Adi; Franitza, Suzanne; Lider, Ofer. Heterologous desensitization of T cell functions by CCR5 and CXCR4 ligands: inhibition of cellular signaling, adhesion and chemotaxis. International Immunology. 2003;15(1):29-38.  PubMed
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Suzuki, Yasuhiro; Nakagomi, Saya; Namikawa, Kazuhiko; Kiryu-Seo, Sumiko; Inagaki, Naoyuki; Kaibuchi, Kozo; Aizawa, Hitoshi; Kikuchi, Kenjiro; Kiyama, Hiroshi. Collapsin response mediator protein-2 accelerates axon regeneration of nerve-injured motor neurons of rat. Journal Of Neurochemistry. 2003;86(4):1042-50.  PubMed
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Chaipinyo, Kanda; Oakes, Barry W; van Damme, Marie-Paule I. Effects of growth factors on cell proliferation and matrix synthesis of low-density, primary bovine chondrocytes cultured in collagen I gels. Journal Of Orthopaedic Research : Official Publication Of The Orthopaedic Research Society. 2002;20(5):1070-8.  PubMed
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Itoh, Takehiro; Kacchi, Masayuki; Abe, Hiroyuki; Sendai, Yutaka; Hoshi, Hiroyoshi. Growth, antrum formation, and estradiol production of bovine preantral follicles cultured in a serum-free medium. Biology Of Reproduction. 2002;67(4):1099-105.  PubMed
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Kondo, Takako; Ohta, Toshiro; Igura, Koichi; Hara, Yukihiko; Kaji, Kazuhiko. Tea catechins inhibit angiogenesis in vitro, measured by human endothelial cell growth, migration and tube formation, through inhibition of VEGF receptor binding. Cancer Letters. 2002;180(2):139-44.  PubMed
- Comments: IAC 3D culture
Weaver, Valerie M; Lelièvre, Sophie; Lakins, Johnathon N; Chrenek, Micah A; Jones, Jonathan C R; Giancotti, Filippo; Werb, Zena; Bissell, Mina J. beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium. Cancer Cell. 2002;2(3):205-16.  PubMed
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Igura, K; Ohta, T; Kuroda, Y; Kaji, K. Resveratrol and quercetin inhibit angiogenesis in vitro. Cancer Letters. 2001;171(1):11-6.  PubMed
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Simian, M; Hirai, Y; Navre, M; Werb, Z; Lochter, A; Bissell, M J. The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. Development (Cambridge, England). 2001;128(16):3117-31.  PubMed
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Takezawa, T; Inoue, M; Aoki, S; Sekiguchi, M; Wada, K; Anazawa, H; Hanai, N. Concept for organ engineering: a reconstruction method of rat liver for in vitro culture. Tissue Engineering. 2000;6(6):641-50.  PubMed
- Comments: IAC 3D culture
Tanabe, K; Tachibana, T; Yamashita, T; Che, Y H; Yoneda, Y; Ochi, T; Tohyama, M; Yoshikawa, H; Kiyama, H. The small GTP-binding protein TC10 promotes nerve elongation in neuronal cells, and its expression is induced during nerve regeneration in rats. The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience. 2000;20(11):4138-44.  PubMed
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Hirai, Y; Lochter, A; Galosy, S; Koshida, S; Niwa, S; Bissell, M J. Epimorphin functions as a key morphoregulator for mammary epithelial cells. The Journal Of Cell Biology. 1998;140(1):159-69.  PubMed
- Comments: IAC 3D culture
Lelièvre, S A; Weaver, V M; Nickerson, J A; Larabell, C A; Bhaumik, A; Petersen, O W; Bissell, M J. Tissue phenotype depends on reciprocal interactions between the extracellular matrix and the structural organization of the nucleus. Proceedings Of The National Academy Of Sciences Of The United States Of America. 1998;95(25):14711-6.  PubMed
- Comments: IAC 3D culture
Matsusaki, M; Ochi, M; Uchio, Y; Shu, N; Kurioka, H; Kawasaki, K; Adachi, N. Effects of basic fibroblast growth factor on proliferation and phenotype expression of chondrocytes embedded in collagen gel. General Pharmacology. 1998;31(5):759-64.  PubMed
- Comments: IAC 3D culture
Hirota, H; Kiyama, H; Kishimoto, T; Taga, T. Accelerated Nerve Regeneration in Mice by upregulated expression of interleukin (IL) 6 and IL-6 receptor after trauma. The Journal Of Experimental Medicine. 1996;183(6):2627-34.  PubMed
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Laoide, B M; Courty, Y; Gastinne, I; Thibaut, C; Kellermann, O; Rougeon, F. Immortalised mouse submandibular epithelial cell lines retain polarised structural and functional properties. Journal Of Cell Science. 1996;109 ( Pt 12)( 9013327):2789-800.  PubMed
- Comments: IAC 3D culture
Kobayashi, S; Miyamoto, T; Kimura, I; Kimura, M. Inhibitory effect of isoliquiritin, a compound in licorice root, on angiogenesis in vivo and tube formation in vitro. Biological & Pharmaceutical Bulletin. 1995;18(10):1382-6.  PubMed
- Comments: IAC 3D culture
Song, Xiaoyu; Nihashi, Yuma; Imai, Yukiko; Mori, Nobuhito; Kagaya, Noritaka; Suenaga, Hikaru; Shin-Ya, Kazuo; Yamamoto, Masamichi; Setoyama, Daiki; Kunisaki, Yuya; Kida, Yasuyuki S. Collagen Lattice Model, Populated with Heterogeneous Cancer-Associated Fibroblasts, Facilitates Advanced Reconstruction of Pancreatic Cancer Microenvironment. International Journal Of Molecular Sciences. 2024;25(7)  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Inagaki, Satoshi; Morimoto, Yuya; Suzuki, Ikuo K; Emoto, Kazuo; Takeuchi, Shoji. Co-culture system of human skin equivalents with mouse neural spheroids. Journal Of Bioscience And Bioengineering. 2023;136(3):239-245.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Kasahara, Keitaro; Muramatsu, Jumpei; Kurashina, Yuta; Miura, Shigenori; Miyata, Shogo; Onoe, Hiroaki. Spatiotemporal single-cell tracking analysis in 3D tissues to reveal heterogeneous cellular response to mechanical stimuli. Science Advances. 2023;9(41):eadf9917.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Dance, Yoseph W; Obenreder, Mackenzie C; Seibel, Alex J; Meshulam, Tova; Ogony, Joshua W; Lahiri, Nikhil; Pacheco-Spann, Laura; Radisky, Derek C; Layne, Matthew D; Farmer, Stephen R; Nelson, Celeste M; Tien, Joe. Adipose Cells Induce Escape from an Engineered Human Breast Microtumor Independently of their Obesity Status. Cellular And Molecular Bioengineering. 2023;16(1):23-39.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Machahua, Carlos; Vicens-Zygmunt, Vanesa; Ríos-Martín, Jesús; Llatjós, Roger; Escobar-Campuzano, Ignacio; Molina-Molina, María; Montes-Worboys, Ana. Collagen 3D matrices as a model for the study of cell behavior in pulmonary fibrosis. Experimental Lung Research. 2022;48(3):126-136.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Seibel, Alex J; Kelly, Owen M; Dance, Yoseph W; Nelson, Celeste M; Tien, Joe. Role of Lymphatic Endothelium in Vascular Escape of Engineered Human Breast Microtumors. Cellular And Molecular Bioengineering. 2022;15(6):553-569.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Kida, Yasuyuki S. Applicability of Artificial Vascularized Liver Tissue to Proteomic Analysis. Micromachines. 2021;12(4)  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Ota, Yukiko; Yoshida, Hiroyuki; Endo, Yoko; Sayo, Tetsuya; Takahashi, Yoshito. A Connecting Link between Hyaluronan Synthase 3-Mediated Hyaluronan Production and Epidermal Function. International Journal Of Molecular Sciences. 2022;23(5)  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Dance, Yoseph W; Meshulam, Tova; Seibel, Alex J; Obenreder, Mackenzie C; Layne, Matthew D; Nelson, Celeste M; Tien, Joe. Adipose Stroma Accelerates the Invasion and Escape of Human Breast Cancer Cells from an Engineered Microtumor. Cellular And Molecular Bioengineering. 2022;15(1):15-29.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Endo, Yoko; Yoshida, Hiroyuki; Ota, Yukiko; Akazawa, Yumiko; Sayo, Tetsuya; Hanai, Ushio; Imagawa, Kotaro; Sasaki, Masashi; Takahashi, Yoshito. Accelerated human epidermal turnover driven by increased hyaluronan production. Journal Of Dermatological Science. 2021;101(2):123-133.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Morikura, Takashi; Miyata, Shogo. Mechanical Intermittent Compression Affects the Progression Rate of Malignant Melanoma Cells in a Cycle Period-Dependent Manner. Diagnostics (Basel, Switzerland). 2021;11(6)  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Uetsuki, Ryo; Higashikawa, Koichiro; Okuda, Satoshi; Yamakado, Nao; Ishida, Fumi; Rizqiawan, Andra; Ono, Shigehiro; Takechi, Masaaki; Mizuta, Kuniko; Shigeishi, Hideo; Kamata, Nobuyuki; Tobiume, Kei. The squamous cell carcinoma cell line OM-1 retains both p75-dependent stratified epithelial progenitor potential and cancer stem cell properties. Biochemistry And Biophysics Reports. 2021;26( 34041369):101003.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Sharma, Kunal; Thacker, Vivek V; Dhar, Neeraj; Clapés Cabrer, Maria; Dubois, Anaëlle; Signorino-Gelo, François; Mullenders, Jasper; Knott, Graham W; Clevers, Hans; McKinney, John D. Early invasion of the bladder wall by solitary bacteria protects UPEC from antibiotics and neutrophil swarms in an organoid model. Cell Reports. 2021;36(3):109351.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Kimura, Shun; Tsuchiya, Ayako; Ogawa, Miho; Ono, Miki; Suda, Nao; Sekimoto, Kaori; Takeo, Makoto; Tsuji, Takashi. Tissue-scale tensional homeostasis in skin regulates structure and physiological function. Communications Biology. 2020;3(1):637.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Miyazaki, Kaoru; Togo, Shinsaku; Okamoto, Reiko; Idiris, Alimjan; Kumagai, Hiromichi; Miyagi, Yohei. Collective cancer cell invasion in contact with fibroblasts through integrin-α5β1/fibronectin interaction in collagen matrix. Cancer Science. 2020;111(12):4381-4392.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Kida, Yasuyuki S. Expression of genes involved in drug metabolism differs between perfusable 3D liver tissue and conventional 2D-cultured hepatocellular carcinoma cells. Febs Open Bio. 2020;10(10):1985-2002.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Akagi, Yuka; Imai, Yukiko; Takayama, Yuzo; Kida, Yasuyuki S. Fabrication of Perfusable Vascular Channels and Capillaries in 3D Liver-like Tissue. Scientific Reports. 2020;10(1):5646.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Miyazaki, Kaoru; Oyanagi, Jun; Hoshino, Daisuke; Togo, Shinsaku; Kumagai, Hiromichi; Miyagi, Yohei. Cancer cell migration on elongate protrusions of fibroblasts in collagen matrix. Scientific Reports. 2019;9(1):292.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Muraguchi, Taichi; Nanba, Daisuke; Nishimura, Emi K; Tashiro, Tomoko. IGF-1R deficiency in human keratinocytes disrupts epidermal homeostasis and stem cell maintenance. Journal Of Dermatological Science. 2019;94(2):298-305.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Akimoto, Naonari; Nakamura, Kodai; Hijioka, Hiroshi; Kume, Kenichi; Matsumura, Yoshiaki; Sugiura, Tsuyoshi. Transfection of T-Box Transcription Factor BRACHYURY and SOX2 Synergistically Promote Self-Renewal and Invasive Phenotype in Oral Cancer Cells. International Journal Of Molecular Sciences. 2018;19(11)  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Matsuura-Hachiya, Yuko; Arai, Koji Y; Muraguchi, Taichi; Sasaki, Tasuku; Nishiyama, Toshio. Type IV collagen aggregates promote keratinocyte proliferation and formation of epidermal layer in human skin equivalents. Experimental Dermatology. 2018;27(5):443-448.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Morimoto, Yuya; Takeuchi, Shoji. Perfusable and stretchable 3D culture system for skin-equivalent. Biofabrication. 2018;11(1):011001.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Pham, Trung Quang; Kawaue, Takumi; Hoshi, Takayuki; Tanaka, Yoshihiro; Miyata, Takaki; Sano, Akihito. Role of extrinsic mechanical force in the development of the RA-I tactile mechanoreceptor. Scientific Reports. 2018;8(1):11085.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Sakamoto, Naoya; Ueki, Yosuke; Oi, Masaki; Kiuchi, Takuya; Sato, Masaaki. Fluid shear stress suppresses ICAM-1-mediated transendothelial migration of leukocytes in coculture model. Biochemical And Biophysical Research Communications. 2018;502(3):403-408.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Mori, Nobuhito; Morimoto, Yuya; Takeuchi, Shoji. Skin integrated with perfusable vascular channels on a chip. Biomaterials. 2017;116( 27914266):48-56.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Uehara, Kazuki; Hara, Masao; Matsuo, Toshiki; Namiki, Go; Watanabe, Mutsuto; Nomura, Yoshihiro. Hyaluronic acid secretion by synoviocytes alters under cyclic compressive load in contracted collagen gels. Cytotechnology. 2015;67(1):19-26.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Arai, Koji Y; Fujioka, Atsuko; Okamura, Ryoko; Nishiyama, Toshio. Stimulatory effect of fibroblast-derived prostaglandin E₂ on keratinocyte stratification in the skin equivalent. Wound Repair And Regeneration : Official Publication Of The Wound Healing Society [And] The European Tissue Repair Society. 2014;22(6):701-11.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Arai, Koji Y; Sugimoto, Mami; Ito, Kanako; Ogura, Yuki; Akutsu, Nobuko; Amano, Satoshi; Adachi, Eijiro; Nishiyama, Toshio. Repeated folding stress-induced morphological changes in the dermal equivalent. Skin Research And Technology : Official Journal Of International Society For Bioengineering And The Skin (Isbs) [And] International Society For Digital Imaging Of Skin (Isdis) [And] International Society For Skin Imaging (Issi). 2014;20(4):399-408.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Hara, Masao; Nakashima, Masahiro; Fujii, Takahiro; Uehara, Kazuki; Yokono, Chisako; Hashizume, Ron; Nomura, Yoshihiro. Construction of collagen gel scaffolds for mechanical stress analysis. Bioscience, Biotechnology, And Biochemistry. 78(3):458-61.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Rizqiawan, Andra; Tobiume, Kei; Okui, Gaku; Yamamoto, Kazuhiro; Shigeishi, Hideo; Ono, Shigehiro; Shimasue, Hiroshi; Takechi, Masaaki; Higashikawa, Koichiro; Kamata, Nobuyuki. Autocrine galectin-1 promotes collective cell migration of squamous cell carcinoma cells through up-regulation of distinct integrins. Biochemical And Biophysical Research Communications. 2013;441(4):904-10.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Shimizu, Kazuya; Chiba, Sachie; Hori, Yuichi. Identification of a novel subpopulation of tumor-initiating cells from gemcitabine-resistant pancreatic ductal adenocarcinoma patients. Plos One. 8(11):e81283.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Arai, Koji Y; Ono, Mariko; Kudo, Chikako; Fujioka, Atsuko; Okamura, Ryoko; Nomura, Yoshihiro; Nishiyama, Toshio. IL-1beta stimulates activin betaA mRNA expression in human skin fibroblasts through the MAPK pathways, the nuclear factor-kappaB pathway, and prostaglandin E2. Endocrinology. 2011;152(10):3779-90.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Murakami, Shizuko; Ohki-Hamazaki, Hiroko; Watanabe, Keisuke; Ikenaka, Kazuhiro; Ono, Katsuhiko. Netrin 1 provides a chemoattractive cue for the ventral migration of GnRH neurons in the chick forebrain. The Journal Of Comparative Neurology. 2010;518(11):2019-34.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Higashikawa, Koichiro; Yoneda, Shingo; Tobiume, Kei; Saitoh, Masao; Taki, Masayuki; Mitani, Yoshitsugu; Shigeishi, Hideo; Ono, Shigehiro; Kamata, Nobuyuki. DeltaNp63alpha-dependent expression of Id-3 distinctively suppresses the invasiveness of human squamous cell carcinoma. International Journal Of Cancer. 2009;124(12):2837-44.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Sharp, T; Kingston, J; Grahame-Smith, D G. Repeated ECS enhances dopamine D-1 but not D-2 agonist-induced behavioural responses in rats. Psychopharmacology. 100(1):110-4.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Azuma, Chinatsu; Tohyama, Harukazu; Nakamura, Hideki; Kanaya, Fuminori; Yasuda, Kazunori. Antibody neutralization of TGF-beta enhances the deterioration of collagen fascicles in a tissue-cultured tendon matrix with ex vivo fibroblast infiltration. Journal Of Biomechanics. 40(10):2184-90.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Higashikawa, Koichiro; Yoneda, Shingo; Tobiume, Kei; Taki, Masayuki; Shigeishi, Hideo; Kamata, Nobuyuki. Snail-induced down-regulation of DeltaNp63alpha acquires invasive phenotype of human squamous cell carcinoma. Cancer Research. 2007;67(19):9207-13.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Ikema, Yasunari; Tohyama, Harukazu; Yamamoto, Ei; Kanaya, Fuminori; Yasuda, Kazunori. Ex vivo infiltration of fibroblasts into the tendon deteriorates the mechanical properties of tendon fascicles but not those of tendon bundles. Clinical Biomechanics (Bristol, Avon). 2007;22(1):120-6.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Noguchi, Chika; Umino, Takeshi; Miyazaki, Yasunari; Jinta, Torahiko; Usui, Yutaka; Yoshizawa, Yasuyuki. TGF-beta and glutathione promote tissue repair in cigarette smoke induced injury. Journal Of Medical And Dental Sciences. 2007;54(1):109-16.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Yaguchi, Yuichiro; Wada, Kota; Uchimizu, Hirotaka; Tanaka, Yasuhiro; Kojima, Hiromi; Moriyama, Hiroshi. Middle ear mucosa regeneration by grafting of artificial mucosa. Acta Oto-Laryngologica. 2007;127(10):1038-44.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Hirai, Kazuya; Kikuchi, Shiro; Kurita, Astushi; Ohashi, Shihoka; Adachi, Eijiro; Matsuoka, Yasuhiro; Nagata, Kazuhiro; Watanabe, Masahiko. Immunohistochemical distribution of heat shock protein 47 (HSP47) in scirrhous carcinoma of the stomach. Anticancer Research. 2006;26(1A):71-8.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Wada, Kota; Tanaka, Yasuhiro; Kojima, Hiromi; Inamatsu, Mutsumi; Yoshizato, Katsutoshi; Moriyama, Hiroshi. In vitro reconstruction of a three-dimensional middle ear mucosal organ and its in vivo transplantation. Acta Oto-Laryngologica. 2006;126(8):801-10.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Ikema, Y; Tohyama, H; Nakamura, H; Kanaya, F; Yasuda, K. Growth kinetics and integrin expression of fibroblasts infiltrating devitalised patellar tendons are different from those of intrinsic fibroblasts. The Journal Of Bone And Joint Surgery. British Volume. 2005;87(12):1689-93.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Tanaka, Yasuhiro; Yaguchi, Yuichiro; Wada, Kota; Kojima, Hiromi; Moriyama, Hiroshi. Creation of a cholesteatoma model using three-dimensional cultured skin equivalents. The Laryngoscope. 2005;115(8):1421-7.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Miyashita, H; Hakamata, Y; Kobayashi, E; Kobayashi, K. Characterization of hair follicles induced in implanted, cultured rat keratinocyte sheets. Experimental Dermatology. 2004;13(8):491-8.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Berry, Catherine C; Shelton, Julia C; Bader, Dan L; Lee, David A. Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels. Tissue Engineering. 2003;9(4):613-24.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Kikuchi, Kaoru; Kishino, Akiyoshi; Konishi, Osamu; Kumagai, Kazuo; Hosotani, Nobuo; Saji, Ikutaro; Nakayama, Chikao; Kimura, Toru. In vitro and in vivo characterization of a novel semaphorin 3A inhibitor, SM-216289 or xanthofulvin. The Journal Of Biological Chemistry. 2003;278(44):42985-91.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Hubert, P; van den Brüle, F; Giannini, S L; Franzen-Detrooz, E; Boniver, J; Delvenne, P. Colonization of in vitro-formed cervical human papillomavirus- associated (pre)neoplastic lesions with dendritic cells: role of granulocyte/macrophage colony-stimulating factor. The American Journal Of Pathology. 1999;154(3):775-84.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Sato, A; Hamazaki, T; Oomura, T; Osada, H; Kakeya, M; Watanabe, M; Nakamura, T; Nakamura, Y; Koshikawa, N; Yoshizaki, I; Aizawa, S; Yoda, S; Ogiso, A; Takaoki, M; Kohno, Y; Tanaka, H. Effects of microgravity on c-fos gene expression in osteoblast-like MC3T3-E1 cells. Advances In Space Research : The Official Journal Of The Committee On Space Research (Cospar). 24(6):807-13.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Furuyama, A; Kimata, K; Mochitate, K. Assembly of basement membrane in vitro by cooperation between alveolar epithelial cells and pulmonary fibroblasts. Cell Structure And Function. 1997;22(6):603-14.  PubMed
- Comments: I-AC co-culture, Mechanical stress culture
Ashimori, Atsushige; Higashijima, Fumiaki; Ogata, Tadahiko; Sakuma, Ayano; Hamada, Waka; Sunada, Junki; Aoki, Ren; Mikuni, Masanori; Hayashi, Ken'ichiro; Wakuta, Makiko; Yoshimoto, Takuya; Minamoto, Akira; Ko, Ji-Ae; Kimura, Kazuhiro. HIF-1α-dependent upregulation of angiogenic factors by mechanical stimulation in retinal pigment epithelial cells. Disease Models & Mechanisms. 2024;17(4)  PubMed
- Comments: I-AC coating
Hirukawa, Kazuya; Yagi, Hiroshi; Kuroda, Kohei; Watanabe, Masafumi; Nishi, Kotaro; Nagata, Shogo; Abe, Yuta; Kitago, Minoru; Adachi, Shungo; Sudo, Ryo; Kitagawa, Yuko. Novel approach for reconstruction of the three-dimensional biliary system in decellularized liver scaffold using hepatocyte progenitors. Plos One. 19(2):e0297285.  PubMed
- Comments: I-AC coating
Hori, Takeshi; Okae, Hiroaki; Shibata, Shun; Kobayashi, Norio; Kobayashi, Eri H; Oike, Akira; Sekiya, Asato; Arima, Takahiro; Kaji, Hirokazu. Trophoblast stem cell-based organoid models of the human placental barrier. Nature Communications. 2024;15(1):962.  PubMed
- Comments: I-AC coating
Ogawa, Shuhei; Ishii, Takashi; Otani, Takahito; Inai, Yuko; Matsuura, Takashi; Inai, Tetsuichiro. JNK inhibition enhances cell-cell adhesion impaired by desmoglein 3 gene disruption in keratinocytes. Histochemistry And Cell Biology. 2024;161(4):345-357.  PubMed
- Comments: I-AC coating
Tatsuno, Rikito; Ichikawa, Jiro; Komohara, Yoshihiro; Pan, Cheng; Kawasaki, Tomonori; Enomoto, Atsushi; Aoki, Kaoru; Hayakawa, Keiko; Iwata, Shintaro; Jubashi, Takahiro; Haro, Hirotaka. Pivotal role of IL-8 derived from the interaction between osteosarcoma and tumor-associated macrophages in osteosarcoma growth and metastasis via the FAK pathway. Cell Death & Disease. 2024;15(2):108.  PubMed
- Comments: I-AC coating
Karanfil, Aslı Sena; Louis, Fiona; Sowa, Yoshihiro; Matsusaki, Michiya. ECM proteins and cationic polymers coating promote dedifferentiation of patient-derived mature adipocytes to stem cells. Biomaterials Science. 2023;11(23):7623-7638.  PubMed
- Comments: I-AC coating
Kim, Mee-Hae; Tan, Shao Ying; Yamahara, Kenichi; Kino-Oka, Masahiro. An in vitro culture platform to study the extracellular matrix remodeling potential of human mesenchymal stem cells. Acta Biomaterialia. 2023;170( 37619896):376-388.  PubMed
- Comments: I-AC coating
Mishra, Richa; Hannebelle, Melanie; Patil, Vishal P; Dubois, Anaëlle; Garcia-Mouton, Cristina; Kirsch, Gabriela M; Jan, Maxime; Sharma, Kunal; Guex, Nicolas; Sordet-Dessimoz, Jessica; Perez-Gil, Jesus; Prakash, Manu; Knott, Graham W; Dhar, Neeraj; McKinney, John D; Thacker, Vivek V. Mechanopathology of biofilm-like Mycobacterium tuberculosis cords. Cell. 2023;186(23):5135-5150.e28.  PubMed
- Comments: I-AC coating
Nagayama, Kazuaki; Kodama, Fumiki; Wataya, Naoki; Sato, Akiko; Matsumoto, Takeo. Changes in the intra- and extra-mechanical environment of the nucleus in Saos-2 osteoblastic cells during bone differentiation process: Nuclear shrinkage and stiffening in cell differentiation. Journal Of The Mechanical Behavior Of Biomedical Materials. 2023;138( 36565693):105630.  PubMed
- Comments: I-AC coating
Tiskratok, Watcharaphol; Yamada, Masahiro; Watanabe, Jun; Pengyu, Qu; Kimura, Tsuyoshi; Egusa, Hiroshi. Mechanoregulation of Osteoclastogenesis-Inducing Potentials of Fibrosarcoma Cell Line by Substrate Stiffness. International Journal Of Molecular Sciences. 2023;24(10)  PubMed
- Comments: I-AC coating
Tiskratok, Watcharaphol; Yamada, Masahiro; Watanabe, Jun; Kartikasari, Nadia; Kimura, Tsuyoshi; Egusa, Hiroshi. Substrate stiffness controls proinflammatory responses in human gingival fibroblasts. Scientific Reports. 2023;13(1):1358.  PubMed
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Koizumi, Koichi; Shintani, Tomoaki; Hayashido, Yasutaka; Hamada, Atsuko; Higaki, Mirai; Yoshioka, Yukio; Sakamoto, Akihiko; Yanamoto, Souichi; Okamoto, Tetsuji. VEGF-A promotes the motility of human melanoma cells through the VEGFR1-PI3K/Akt signaling pathway. In Vitro Cellular & Developmental Biology. Animal. 2022;58(8):758-770.  PubMed
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Sonoda, Dai; Kamizaki, Koki; Matsuo, Yukiko; Aruga, Kana; Mikubo, Masashi; Yamashita, Keishi; Nishita, Michiru; Minami, Yasuhiro; Satoh, Yukitoshi. Characterization of morphological alterations in micropapillary adenocarcinoma of the lung using an established cell line. Oncology Reports. 2022;47(1)  PubMed
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Yoshimoto, Yuki; Uezumi, Akiyoshi; Ikemoto-Uezumi, Madoka; Tanaka, Kaori; Yu, Xinyi; Kurosawa, Tamaki; Yambe, Shinsei; Maehara, Kazumitsu; Ohkawa, Yasuyuki; Sotomaru, Yusuke; Shukunami, Chisa. Tenogenic Induction From Induced Pluripotent Stem Cells Unveils the Trajectory Towards Tenocyte Differentiation. Frontiers In Cell And Developmental Biology. 10( 35372337):780038.  PubMed
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Akbor, Maruf Mohammad; Kim, Juhyon; Nomura, Mai; Sugioka, Juno; Kurosawa, Nobuyuki; Isobe, Masaharu. A candidate gene of Alzheimer diseases was mutated in senescence-accelerated mouse prone (SAMP) 8 mice. Biochemical And Biophysical Research Communications. 2021;572( 34364289):112-117.  PubMed
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Sakurai, Takuya; Fukutomi, Toshiyuki; Yamamoto, Sachiko; Nozaki, Eriko; Kizaki, Takako. Physical Activity Attenuates the Obesity-Induced Dysregulated Expression of Brown Adipokines in Murine Interscapular Brown Adipose Tissue. International Journal Of Molecular Sciences. 2021;22(19)  PubMed
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Sharma, Kunal; Dhar, Neeraj; Thacker, Vivek V; Simonet, Thomas M; Signorino-Gelo, Francois; Knott, Graham W; McKinney, John D. Dynamic persistence of UPEC intracellular bacterial communities in a human bladder-chip model of urinary tract infection. Elife. 2021;10( 34219648)  PubMed
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Thacker, Vivek V; Sharma, Kunal; Dhar, Neeraj; Mancini, Gian-Filippo; Sordet-Dessimoz, Jessica; McKinney, John D. Rapid endotheliitis and vascular damage characterize SARS-CoV-2 infection in a human lung-on-chip model. Embo Reports. 2021;22(6):e52744.  PubMed
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Wang, Qiongye; Guan, Kelei; Lv, Yuanjun; Zhang, Yingxuan; Yu, Zujiang; Kan, Quancheng. Disturbance of hepatocyte growth and metabolism in a hyperammonemia microenvironment. Archives Of Biochemistry And Biophysics. 2022;716( 34932992):109109.  PubMed
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Hori, Takeshi; Kurosawa, Osamu; Ishihara, Kohei; Mizuta, Taro; Iwata, Hiroo. Three-Dimensional Cell Sheet Construction Method with a Polyester Micromesh Sheet. Tissue Engineering. Part C, Methods. 2020;26(3):170-179.  PubMed
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Miyazono, Shoji; Otani, Takahito; Ogata, Kayoko; Kitagawa, Norio; Iida, Hiroshi; Inai, Yuko; Matsuura, Takashi; Inai, Tetsuichiro. The reduced susceptibility of mouse keratinocytes to retinoic acid may be involved in the keratinization of oral and esophageal mucosal epithelium. Histochemistry And Cell Biology. 2020;153(4):225-237.  PubMed
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Thacker, Vivek V; Dhar, Neeraj; Sharma, Kunal; Barrile, Riccardo; Karalis, Katia; McKinney, John D. A lung-on-chip model of early Mycobacterium tuberculosis infection reveals an essential role for alveolar epithelial cells in controlling bacterial growth. Elife. 2020;9( 33228849)  PubMed
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Yasui, Hiroaki; Kajiyama, Hiroaki; Tamauchi, Satoshi; Suzuki, Shiro; Peng, Yang; Yoshikawa, Nobuhisa; Sugiyama, Mai; Nakamura, Kae; Kikkawa, Fumitaka. CCL2 secreted from cancer-associated mesothelial cells promotes peritoneal metastasis of ovarian cancer cells through the P38-MAPK pathway. Clinical & Experimental Metastasis. 2020;37(1):145-158.  PubMed
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Kawasaki, Yoshihiro; Miyamoto, Masaya; Oda, Takeaki; Matsumura, Kosuke; Negishi, Lumi; Nakato, Ryuichiro; Suda, Sakiko; Yokota, Naoko; Shirahige, Katsuhiko; Akiyama, Tetsu. The novel lncRNA CALIC upregulates AXL to promote colon cancer metastasis. Embo Reports. 2019;20(8):e47052.  PubMed
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Takimoto, Aki; Kokubu, Chikara; Watanabe, Hitomi; Sakuma, Tetsushi; Yamamoto, Takashi; Kondoh, Gen; Hiraki, Yuji; Shukunami, Chisa. Differential transactivation of the upstream aggrecan enhancer regulated by PAX1/9 depends on SOX9-driven transactivation. Scientific Reports. 2019;9(1):4605.  PubMed
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Ueda, Masashi; Sato, Yukiyasu; Horie, Akihito; Tani, Hirohiko; Miyazaki, Yumiko; Okunomiya, Asuka; Matsumoto, Hisanori; Hamanishi, Junzo; Kondoh, Eiji; Mandai, Masaki. Endovascular trophoblast expresses CD59 to evade complement-dependent cytotoxicity. Molecular And Cellular Endocrinology. 2019;490( 30981734):57-67.  PubMed
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Nakamura, Ryosuke; Ishii, Hiroki; Endo, Kaori; Hotta, Asami; Fujii, Eiji; Miyazawa, Keiji; Saitoh, Masao. Reciprocal expression of Slug and Snail in human oral cancer cells. Plos One. 13(7):e0199442.  PubMed
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Ge, Heng'an; Shrestha, Amrit; Liu, Centao; Wu, Peng; Cheng, Biao. MicroRNA 148a-3p promotes Thrombospondin-4 expression and enhances angiogenesis during tendinopathy development by inhibiting Krüppel-like factor 6. Biochemical And Biophysical Research Communications. 2018;502(2):276-282.  PubMed
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Kikkawa, Yamato; Enomoto-Okawa, Yurie; Fujiyama, Aiko; Fukuhara, Takeshi; Harashima, Nozomi; Sugawara, Yumika; Negishi, Yoichi; Katagiri, Fumihiko; Hozumi, Kentaro; Nomizu, Motoyoshi; Ito, Yuji. Internalization of CD239 highly expressed in breast cancer cells: a potential antigen for antibody-drug conjugates. Scientific Reports. 2018;8(1):6612.  PubMed
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Shukunami, Chisa; Takimoto, Aki; Nishizaki, Yuriko; Yoshimoto, Yuki; Tanaka, Seima; Miura, Shigenori; Watanabe, Hitomi; Sakuma, Tetsushi; Yamamoto, Takashi; Kondoh, Gen; Hiraki, Yuji. Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes. Scientific Reports. 2018;8(1):3155.  PubMed
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Hirata, Hiroaki; Samsonov, Mikhail; Sokabe, Masahiro. Actomyosin contractility provokes contact inhibition in E-cadherin-ligated keratinocytes. Scientific Reports. 2017;7( 28406163):46326.  PubMed
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Kriszt, Rókus; Arai, Satoshi; Itoh, Hideki; Lee, Michelle H; Goralczyk, Anna G; Ang, Xiu Min; Cypess, Aaron M; White, Andrew P; Shamsi, Farnaz; Xue, Ruidan; Lee, Jung Yeol; Lee, Sung-Chan; Hou, Yanyan; Kitaguchi, Tetsuya; Sudhaharan, Thankiah; Ishiwata, Shin'ichi; Lane, E Birgitte; Chang, Young-Tae; Tseng, Yu-Hua; Suzuki, Madoka; Raghunath, Michael. Optical visualisation of thermogenesis in stimulated single-cell brown adipocytes. Scientific Reports. 2017;7(1):1383.  PubMed
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Matsumura, K; Kawasaki, Y; Miyamoto, M; Kamoshida, Y; Nakamura, J; Negishi, L; Suda, S; Akiyama, T. The novel G-quadruplex-containing long non-coding RNA GSEC antagonizes DHX36 and modulates colon cancer cell migration. Oncogene. 2017;36(9):1191-1199.  PubMed
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Mobasseri, Rezvan; Tian, Lingling; Soleimani, Masoud; Ramakrishna, Seeram; Naderi-Manesh, Hossein. Bio-active molecules modified surfaces enhanced mesenchymal stem cell adhesion and proliferation. Biochemical And Biophysical Research Communications. 2017;483(1):312-317.  PubMed
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Mukudai, Yoshiki; Zhang, Meilin; Shiogama, Sunao; Kondo, Seiji; Ito, Chihiro; Motohashi, Hiromi; Kato, Kosuke; Fujii, Miharu; Shintani, Satoru; Shigemori, Hideyuki; Yazawa, Kazunaga; Shirota, Tatsuo. Methanol and Butanol Extracts of Paeonia lutea Leaves Repress Metastasis of Squamous Cell Carcinoma. Evidence-Based Complementary And Alternative Medicine : Ecam. 2016( 27293462):6087213.  PubMed
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Nowell, Craig S; Odermatt, Pascal D; Azzolin, Luca; Hohnel, Sylke; Wagner, Erwin F; Fantner, Georg E; Lutolf, Matthias P; Barrandon, Yann; Piccolo, Stefano; Radtke, Freddy. Chronic inflammation imposes aberrant cell fate in regenerating epithelia through mechanotransduction. Nature Cell Biology. 2016;18(2):168-80.  PubMed
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Wang, Qiongye; Wang, Yanfang; Yu, Zujiang; Li, Duolu; Jia, Bin; Li, Jingjing; Guan, Kelei; Zhou, Yubing; Chen, Yanling; Kan, Quancheng. Ammonia-induced energy disorders interfere with bilirubin metabolism in hepatocytes. Archives Of Biochemistry And Biophysics. 2014;555-556( 24878366):16-22.  PubMed
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Soma, Tsutomu; Kishimoto, Jiro; Fisher, David. Isolation of mesenchymal stem cells from human dermis. Methods In Molecular Biology (Clifton, N.j.). 989( 23483401):265-74.  PubMed
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Hori, Takeshi; Jin, Liangjing; Fujii, Ayako; Furihata, Tomomi; Nagahara, Yuko; Chiba, Kan; Hosokawa, Masakiyo. Dexamethasone-mediated transcriptional regulation of rat carboxylesterase 2 gene. Xenobiotica; The Fate Of Foreign Compounds In Biological Systems. 2012;42(7):614-23.  PubMed
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Matsuda, Yoko; Hagio, Masahito; Seya, Tomoko; Ishiwata, Toshiyuki. Fibroblast growth factor receptor 2 IIIc as a therapeutic target for colorectal cancer cells. Molecular Cancer Therapeutics. 2012;11(9):2010-20.  PubMed
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Nadzir, Masrina Mohd; Kino-oka, Masahiro; Sugawara, Katsura; Taya, Masahito. Effect of preservation conditions of collagen substrate on its fibril formation and rabbit chondrocyte morphology. Journal Of Bioscience And Bioengineering. 2012;114(3):360-3.  PubMed
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Senga, Kazunori; Mostov, Keith E; Mitaka, Toshihiro; Miyajima, Atsushi; Tanimizu, Naoki. Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25. Molecular Biology Of The Cell. 2012;23(15):2845-55.  PubMed
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Tanimizu, Naoki; Kikkawa, Yamato; Mitaka, Toshihiro; Miyajima, Atsushi. α1- and α5-containing laminins regulate the development of bile ducts via β1 integrin signals. The Journal Of Biological Chemistry. 2012;287(34):28586-97.  PubMed
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Adachi, Tatsuhiko; Goto, Mitsuaki; Cho, Chong-Su; Akaike, Toshihiro. Modulation of cytochrome P450 gene expression in primary hepatocytes on various artificial extracellular matrices. Biochemical And Biophysical Research Communications. 2011;413(4):577-81.  PubMed
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Matsuda, Yoko; Ishiwata, Toshiyuki; Yamahatsu, Kazuya; Kawahara, Kiyoko; Hagio, Masahito; Peng, Wei-Xia; Yamamoto, Tetsushi; Nakazawa, Nando; Seya, Tomoko; Ohaki, Yoshiharu; Naito, Zenya. Overexpressed fibroblast growth factor receptor 2 in the invasive front of colorectal cancer: a potential therapeutic target in colorectal cancer. Cancer Letters. 2011;309(2):209-19.  PubMed
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Nadzir, Masrina Mohd; Kino-oka, Masahiro; Maruyama, Nao; Sato, Yasuaki; Kim, Mee-Hae; Sugawara, Katsura; Taya, Masahito. Comprehension of terminal differentiation and dedifferentiation of chondrocytes during passage cultures. Journal Of Bioscience And Bioengineering. 2011;112(4):395-401.  PubMed
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Ogimura, Eiichiro; Sekine, Shuichi; Horie, Toshiharu. Bile salt export pump inhibitors are associated with bile acid-dependent drug-induced toxicity in sandwich-cultured hepatocytes. Biochemical And Biophysical Research Communications. 2011;416(3-4):313-7.  PubMed
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Oya, Koki; Sakamoto, Naoya; Ohashi, Toshiro; Sato, Masaaki. Combined stimulation with cyclic stretching and hypoxia increases production of matrix metalloproteinase-9 and cytokines by macrophages. Biochemical And Biophysical Research Communications. 2011;412(4):678-82.  PubMed
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Yamada, Yuji; Katagiri, Fumihiko; Hozumi, Kentaro; Kikkawa, Yamato; Nomizu, Motoyoshi. Cell behavior on protein matrices containing laminin α1 peptide AG73. Biomaterials. 2011;32(19):4327-35.  PubMed
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Ishiwata, Toshiyuki; Yamamoto, Tetsushi; Kawahara, Kiyoko; Kawamoto, Yoko; Matsuda, Yoko; Ishiwata, Shunji; Naito, Zenya. Enhanced expression of lumican inhibited the attachment and growth of human embryonic kidney 293 cells. Experimental And Molecular Pathology. 2010;88(3):363-70.  PubMed
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Jung, Stephanie M; Sonoda, Mamiko; Tsuji, Kayoko; Jimi, Atsuo; Nomura, Shosaku; Kanaji, Taisuke; Moroi, Masaaki. Are integrin alpha(2)beta(1), glycoprotein Ib and vWf levels correlated with their contributions to platelet adhesion on collagen under high-shear flow?. Platelets. 21(2):101-11.  PubMed
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Kawasaki, Yoshihiro; Jigami, Takafumi; Furukawa, Shiori; Sagara, Masaki; Echizen, Kanae; Shibata, Yoko; Sato, Rina; Akiyama, Tetsu. The adenomatous polyposis coli-associated guanine nucleotide exchange factor Asef is involved in angiogenesis. The Journal Of Biological Chemistry. 2010;285(2):1199-207.  PubMed
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Nishiyama, Hidetoshi; Suga, Mitsuo; Ogura, Toshihiko; Maruyama, Yuusuke; Koizumi, Mitsuru; Mio, Kazuhiro; Kitamura, Shinichi; Sato, Chikara. Reprint of: Atmospheric scanning electron microscope observes cells and tissues in open medium through silicon nitride film. Journal Of Structural Biology. 2010;172(2):191-202.  PubMed
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Sasai, Nobuaki; Agata, Nobuhide; Inoue-Miyazu, Masumi; Kawakami, Keisuke; Kobayashi, Kunihiko; Sokabe, Masahiro; Hayakawa, Kimihide. Involvement of PI3K/Akt/TOR pathway in stretch-induced hypertrophy of myotubes. Muscle & Nerve. 2010;41(1):100-6.  PubMed
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Sun, Hantang; Kawashima, Nobuyuki; Xu, Jing; Takahashi, Satomi; Suda, Hideaki. Expression of Notch signalling-related genes in normal and differentiating rat dental pulp cells. Australian Endodontic Journal : The Journal Of The Australian Society Of Endodontology Inc. 2010;36(2):54-8.  PubMed
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Suzuki, Tadaki; Yamanouchi, Satoko; Sunden, Yuji; Orba, Yasuko; Kimura, Takashi; Sawa, Hirofumi. Natalizumab has no direct biological effect on JC virus infectivity in permissive human neural cell lines. Journal Of Medical Virology. 2010;82(7):1229-35.  PubMed
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Hannachi Imen, Elloumi; Nakamura, Makiko; Mie, Masayasu; Kobatake, Eiry. Construction of multifunctional proteins for tissue engineering: epidermal growth factor with collagen binding and cell adhesive activities. Journal Of Biotechnology. 2009;139(1):19-25.  PubMed
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Kawasaki, Yoshihiro; Tsuji, Shinnosuke; Sagara, Masaki; Echizen, Kanae; Shibata, Yoko; Akiyama, Tetsu. Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase. The Journal Of Biological Chemistry. 2009;284(33):22436-22443.  PubMed
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LaBarge, Mark A; Nelson, Celeste M; Villadsen, Rene; Fridriksdottir, Agla; Ruth, Jason R; Stampfer, Martha R; Petersen, Ole W; Bissell, Mina J. Human mammary progenitor cell fate decisions are products of interactions with combinatorial microenvironments. Integrative Biology : Quantitative Biosciences From Nano To Macro. 2009;1(1):70-9.  PubMed
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Nakagawa, Hiroyuki; Suzuki, Hiroshi; Machida, Satoshi; Suzuki, Junko; Ohashi, Kazuyo; Jin, Mingyue; Miyamoto, Shigeaki; Terasaki, Asako G. Contribution of the LIM domain and nebulin-repeats to the interaction of Lasp-2 with actin filaments and focal adhesions. Plos One. 2009;4(10):e7530.  PubMed
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Sagara, M; Kawasaki, Y; Iemura, S-i; Natsume, T; Takai, Y; Akiyama, T. Asef2 and Neurabin2 cooperatively regulate actin cytoskeletal organization and are involved in HGF-induced cell migration. Oncogene. 2009;28(10):1357-65.  PubMed
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Uehara, Hironori; Ikai, Atsushi; Osada, Toshiya. Detection of mRNA in single living cells using AFM nanoprobes. Methods In Molecular Biology (Clifton, N.j.). 544( 19488726):599-608.  PubMed
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Hattori, Hidemi; Nogami, Yashiro; Tanaka, Tomohiro; Amano, Yoshiko; Fukuda, Koichi; Kishimoto, Satoko; Kanatani, Yasuhiro; Nakamura, Shingo; Takase, Bonpei; Ishihara, Masayuki. Expansion and characterization of adipose tissue-derived stromal cells cultured with low serum medium. Journal Of Biomedical Materials Research. Part B, Applied Biomaterials. 2008;87(1):229-36.  PubMed
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Hoshiba, Takashi; Wakejima, Mai; Cho, Chong-Su; Shiota, Goshi; Akaike, Toshihiro. Different regulation of hepatocyte behaviors between natural extracellular matrices and synthetic extracellular matrices by hepatocyte growth factor. Journal Of Biomedical Materials Research. Part A. 2008;85(1):228-35.  PubMed
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Kano, Kyoko; Yamato, Masayuki; Okano, Teruo. Ectopic transplantation of hepatocyte sheets fabricated with temperature-responsive culture dishes. Hepatology Research : The Official Journal Of The Japan Society Of Hepatology. 38(11):1140-7.  PubMed
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Kuriyama, Isoko; Mizuno, Takeshi; Fukudome, Keishi; Kuramochi, Kouji; Tsubaki, Kazunori; Usui, Takeo; Imamoto, Naoko; Sakaguchi, Kengo; Sugawara, Fumio; Yoshida, Hiromi; Mizushina, Yoshiyuki. Effect of dehydroaltenusin-C12 derivative, a selective DNA polymerase alpha inhibitor, on DNA replication in cultured cells. Molecules (Basel, Switzerland). 2008;13(12):2948-61.  PubMed
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Hoshiba, Takashi; Nagahara, Hikaru; Cho, Chong-Su; Tagawa, Yoh-ichi; Akaike, Toshihiro. Primary hepatocyte survival on non-integrin-recognizable matrices without the activation of Akt signaling. Biomaterials. 2007;28(6):1093-104.  PubMed
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Kim, Sang-Heon; Akaike, Toshihiro. Epidermal growth factor signaling for matrix-dependent cell proliferation and differentiation in primary cultured hepatocytes. Tissue Engineering. 2007;13(3):601-9.  PubMed
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Maruyama, Masataka; Matsunaga, Tamihide; Harada, Eri; Ohmori, Shigeru. Comparison of basal gene expression and induction of CYP3As in HepG2 and human fetal liver cells. Biological & Pharmaceutical Bulletin. 2007;30(11):2091-7.  PubMed
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Moroi, M; Jung, S M. A mechanism to safeguard platelet adhesion under high shear flow: von Willebrand factor-glycoprotein Ib and integrin alphabeta-collagen interactions make complementary, collagen-type-specific contributions to adhesion. Journal Of Thrombosis And Haemostasis : Jth. 2007;5(4):797-803.  PubMed
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Nakajima, Masafumi; Ishimuro, Toshinari; Kato, Koichi; Ko, In-Kap; Hirata, Isao; Arima, Yusuke; Iwata, Hiroo. Combinatorial protein display for the cell-based screening of biomaterials that direct neural stem cell differentiation. Biomaterials. 2007;28(6):1048-60.  PubMed
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Kobayashi, Yuko; Katanosaka, Yuki; Iwata, Yuko; Matsuoka, Masayuki; Shigekawa, Munekazu; Wakabayashi, Shigeo. Identification and characterization of GSRP-56, a novel Golgi-localized spectrin repeat-containing protein. Experimental Cell Research. 2006;312(16):3152-64.  PubMed
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Usui, Joichi; Yamada, Risa; Kanemoto, Katsuyoshi; Koyama, Akio; Nagata, Michio. Murine metanephric mesenchyme possesses characteristics of vascular endothelial cells in vitro. Nephron. Experimental Nephrology. 102(3-4):e93-8.  PubMed
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Bhawal, Ujjal K; Ozaki, Yoshie; Nishimura, Masahiro; Sugiyama, Masaru; Sasahira, Tomonori; Nomura, Yuji; Sato, Fuyuki; Fujimoto, Katsumi; Sasaki, Nobuyuki; Ikeda, Masa-Aki; Tsuji, Koichiro; Kuniyasu, Hiroki; Kato, Yukio. Association of expression of receptor for advanced glycation end products and invasive activity of oral squamous cell carcinoma. Oncology. 69(3):246-55.  PubMed
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Kaneko, Hiroyuki; Okai, Murasaki; Murabe, Naoyuki; Shimizu, Takahiko; Ikegami, Susumu; Dan-Sohkawa, Marina. Fibrous component of the blastocoelic extracellular matrix shapes epithelia in concert with mesenchyme cells in starfish embryos. Developmental Dynamics : An Official Publication Of The American Association Of Anatomists. 2005;232(4):915-27.  PubMed
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Katayama, Masafumi; Shoji, Masaru; Satomi, Susumu. Differential growth properties of normal and malignant esophageal epithelial cells: a possible cross talk between transforming growth factor-beta1 and epidermal growth factor signaling. The Tohoku Journal Of Experimental Medicine. 2005;206(1):61-71.  PubMed
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Kino-oka, Masahiro; Maeda, Yoshikatsu; Ota, Yuka; Yashiki, Shino; Sugawara, Katsura; Yamamoto, Takeyuki; Taya, Masahito. Process design of chondrocyte cultures with monolayer growth for cell expansion and subsequent three-dimensional growth for production of cultured cartilage. Journal Of Bioscience And Bioengineering. 2005;100(1):67-76.  PubMed
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Koshikawa, Masao; Mukoyama, Masashi; Mori, Kiyoshi; Suganami, Takayoshi; Sawai, Kazutomo; Yoshioka, Tetsuro; Nagae, Tetsuya; Yokoi, Hideki; Kawachi, Hiroshi; Shimizu, Fujio; Sugawara, Akira; Nakao, Kazuwa. Role of p38 mitogen-activated protein kinase activation in podocyte injury and proteinuria in experimental nephrotic syndrome. Journal Of The American Society Of Nephrology : Jasn. 2005;16(9):2690-701.  PubMed
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Kudo, Susumu; Yamaguchi, Ryuhei; Ikeda, Mariko; Tanishita, Kazuo. Effect of fluid force on vascular cell function. Journal Of Physiological Anthropology And Applied Human Science. 2005;24(4):459-61.  PubMed
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Saji, Shigehira; Kawakami, Masayo; Hayashi, Shin-Ichi; Yoshida, Nobuyuki; Hirose, Makiko; Horiguchi, Shin-Ichiro; Itoh, Akihiro; Funata, Nobuaki; Schreiber, Stuart L; Yoshida, Minoru; Toi, Masakazu. Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. Oncogene. 2005;24(28):4531-9.  PubMed
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Sato, Yukiyasu; Fujiwara, Hiroshi; Zeng, Bin-Xiang; Higuchi, Toshihiro; Yoshioka, Shinya; Fujii, Shingo. Platelet-derived soluble factors induce human extravillous trophoblast migration and differentiation: platelets are a possible regulator of trophoblast infiltration into maternal spiral arteries. Blood. 2005;106(2):428-35.  PubMed
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Tsubota, Yoshiaki; Yasuda, Chie; Kariya, Yoshinobu; Ogawa, Takashi; Hirosaki, Tomomi; Mizushima, Hiroto; Miyazaki, Kaoru. Regulation of biological activity and matrix assembly of laminin-5 by COOH-terminal, LG4-5 domain of alpha3 chain. The Journal Of Biological Chemistry. 2005;280(15):14370-7.  PubMed
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Date, Tomoko; Kato, Takanobu; Miyamoto, Michiko; Zhao, Zijiang; Yasui, Kotaro; Mizokami, Masashi; Wakita, Takaji. Genotype 2a hepatitis C virus subgenomic replicon can replicate in HepG2 and IMY-N9 cells. The Journal Of Biological Chemistry. 2004;279(21):22371-6.  PubMed
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Hirano, Shuichi; Yonezawa, Tomoko; Hasegawa, Haruko; Hattori, Shunji; Greenhill, Nicholas S; Davis, Paul F; Sage, E Helene; Ninomiya, Yoshifumi. Astrocytes express type VIII collagen during the repair process of brain cold injury. Biochemical And Biophysical Research Communications. 2004;317(2):437-43.  PubMed
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Itoh, Kohji; Satoh, Yurie; Kadota, Yoshito; Oheda, Yukako; Kuwahara, Jun; Shimmoto, Michie; Sakuraba, Hitoshi. Expression of lysosomal protective protein/cathepsin A in a stably transformed human neuroblastoma cell line during bi-directional differentiation into neuronal and Schwannian cells. Neurochemistry International. 2004;44(6):447-57.  PubMed
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Kariya, Yoshinobu; Miyazaki, Kaoru. The basement membrane protein laminin-5 acts as a soluble cell motility factor. Experimental Cell Research. 2004;297(2):508-20.  PubMed
- Comments: I-AC coating
Kawamura, Kazuhiro; Takano, Kazunori; Suetsugu, Shiro; Kurisu, Shusaku; Yamazaki, Daisuke; Miki, Hiroaki; Takenawa, Tadaomi; Endo, Takeshi. N-WASP and WAVE2 acting downstream of phosphatidylinositol 3-kinase are required for myogenic cell migration induced by hepatocyte growth factor. The Journal Of Biological Chemistry. 2004;279(52):54862-71.  PubMed
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Kim, Sang-Heon; Hoshiba, Takashi; Akaike, Toshihiro. Hepatocyte behavior on synthetic glycopolymer matrix: inhibitory effect of receptor-ligand binding on hepatocyte spreading. Biomaterials. 2004;25(10):1813-23.  PubMed
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Satoh, Yurie; Kadota, Yoshito; Oheda, Yukako; Kuwahara, Jun; Aikawa, Seiichi; Matsuzawa, Fumiko; Doi, Hirofumi; Aoyagi, Takaaki; Sakuraba, Hitoshi; Itoh, Kohji. Microbial serine carboxypeptidase inhibitors--comparative analysis of actions on homologous enzymes derived from man, yeast and wheat. The Journal Of Antibiotics. 2004;57(5):316-25.  PubMed
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Takashima, Seiji; Ise, Hirohiko; Zhao, Peng; Akaike, Toshihiro; Nikaido, Toshio. Human amniotic epithelial cells possess hepatocyte-like characteristics and functions. Cell Structure And Function. 2004;29(3):73-84.  PubMed
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Pang, Tianxiang; Wakabayashi, Shigeo; Shigekawa, Munekazu. Expression of calcineurin B homologous protein 2 protects serum deprivation-induced cell death by serum-independent activation of Na+/H+ exchanger. The Journal Of Biological Chemistry. 2002;277(46):43771-7.  PubMed
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Ito, T; Yasui, K; Mukaigawa, J; Katsume, A; Kohara, M; Mitamura, K. Acquisition of susceptibility to hepatitis C virus replication in HepG2 cells by fusion with primary human hepatocytes: establishment of a quantitative assay for hepatitis C virus infectivity in a cell culture system. Hepatology (Baltimore, Md.). 2001;34(3):566-72.  PubMed
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Saito, Y; Tsubuki, S; Ito, H; Kawashima, S. Possible involvement of a novel protease in neurite outgrowth of PC12 cells. Neuroscience Research. Supplement : The Official Journal Of The Japan Neuroscience Society. 13( 2088345):S97-101.  PubMed
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Hamilton, Nick J I; Tait, Angela; Weil, Ben; Daniels, Julie. The Use of a Dehydrated Cellularized Collagen Matrix to Replace Fibrotic Vocal Fold Mucosa. The Laryngoscope. 2024;134(2):882-893.  PubMed
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Mashiyama, Shota; Hemmi, Runa; Sato, Takeru; Kato, Atsuya; Taniguchi, Tatsuo; Yamada, Masumi. Pushing the limits of microfluidic droplet production efficiency: engineering microchannels with seamlessly implemented 3D inverse colloidal crystals. Lab On A Chip. 2024;24(2):171-181.  PubMed
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Song, Young Woo; Maekawa, Shogo; Sasaki, Keito; Yoshida, Daichi; Nagai, Masazumi; Ishikawa-Nagai, Shigemi; Da Silva, John; Kim, David Minjoon; Chen, Chia-Yu. Microscopic in-situ analysis of the mucosal healing around implants treated by protease activated receptor 4-agonist peptide or perpendicularly protruded type I collagen in rats. Journal Of Biomedical Materials Research. Part B, Applied Biomaterials. 2024;112(1):e35330.  PubMed
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Kurashina, Yuta; Fukada, Keisuke; Itai, Shun; Akizuki, Shuichi; Sato, Ryo; Masuda, Akari; Tani, Hidenori; Fujita, Jun; Fukuda, Keiichi; Tohyama, Shugo; Onoe, Hiroaki. Hydrogel-Sheathed hiPSC-Derived Heart Microtissue Enables Anchor-Free Contractile Force Measurement. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). 2023;10(35):e2301831.  PubMed
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Takeya, Hiroaki; Itai, Shun; Kimura, Hiroo; Kurashina, Yuta; Amemiya, Tsuyoshi; Nagoshi, Narihito; Iwamoto, Takuji; Sato, Kazuki; Shibata, Shinsuke; Matsumoto, Morio; Onoe, Hiroaki; Nakamura, Masaya. Schwann cell-encapsulated chitosan-collagen hydrogel nerve conduit promotes peripheral nerve regeneration in rodent sciatic nerve defect models. Scientific Reports. 2023;13(1):11932.  PubMed
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Hiroshima, Yuya; Oyama, Yuki; Sawasaki, Kaoru; Nakamura, Masanori; Kimura, Naoyuki; Kawahito, Koji; Fujie, Hiromichi; Sakamoto, Naoya. A Compressed Collagen Construct for Studying Endothelial-Smooth Muscle Cell Interaction Under High Shear Stress. Annals Of Biomedical Engineering. 2022;50(8):951-963.  PubMed
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Itai, Shun; Onoe, Hiroaki. Flexibly Deformable Collagen Hydrogel Tube Reproducing Immunological Tissue Deformation of Blood Vessels as a Pharmacokinetic Testing Model. Advanced Healthcare Materials. 2022;11(1):e2101509.  PubMed
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Jo, Byeongwook; Morimoto, Yuya; Takeuchi, Shoji. Skeletal muscle-adipose cocultured tissue fabricated using cell-laden microfibers and a hydrogel sheet. Biotechnology And Bioengineering. 2022;119(2):636-643.  PubMed
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Kalaimani, Lavanya; Devarajan, Bharanidharan; Namperumalsamy, Venkatesh Prajna; Veerappan, Muthukkaruppan; Daniels, Julie T; Chidambaranathan, Gowri Priya. Hsa-miR-150-5p inhibits Wnt-β-catenin signaling in human corneal epithelial stem cells. Molecular Vision. 28( 36274818):178-191.  PubMed
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Kalaimani, Lavanya; Devarajan, Bharanidharan; Namperumalsamy, Venkatesh Prajna; Veerappan, Muthukkaruppan; Daniels, Julie T; Chidambaranathan, Gowri Priya. Hsa-miR-143-3p inhibits Wnt-β-catenin and MAPK signaling in human corneal epithelial stem cells. Scientific Reports. 2022;12(1):11432.  PubMed
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Maeda, Eijiro; Kawamura, Ryota; Suzuki, Takashi; Matsumoto, Takeo. Rapid fabrication of tendon-like collagen gel via simultaneous fibre alignment and intermolecular cross-linking under mechanical loading. Biomedical Materials (Bristol, England). 2022;17(4)  PubMed
- Comments: I-AC fabricating/coating scaffold
Mazari-Arrighi, Elsa; Okitsu, Teru; Teramae, Hiroki; Aoyagi, Hoshimi; Kiyosawa, Mahiro; Yano, Mariko; Chatelain, François; Fuchs, Alexandra; Takeuchi, Shoji. In vitro proliferation and long-term preservation of functional primary rat hepatocytes in cell fibers. Scientific Reports. 2022;12(1):8813.  PubMed
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Morita, Akihiro; Yamada, Masumi; Utoh, Rie; Momiyama, Kanta; Iwadate, Hideki; Seki, Minoru. Formation of 3D tissues of primary hepatocytes using fibrillized collagen microparticles as intercellular binders. Journal Of Bioscience And Bioengineering. 2022;133(3):265-272.  PubMed
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Wang, Yue; Kanie, Kei; Takezawa, Toshiaki; Horikawa, Miki; Kaneko, Kyoshiro; Sugimoto, Ayako; Yamawaki-Ogata, Aika; Narita, Yuji; Kato, Ryuji. Bi-layered carboxymethyl cellulose-collagen vitrigel dual-surface adhesion-prevention membrane. Carbohydrate Polymers. 2022;285( 35287853):119223.  PubMed
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Yamada, Masahiro; Kimura, Tsuyoshi; Nakamura, Naoko; Watanabe, Jun; Kartikasari, Nadia; He, Xindie; Tiskratok, Watcharaphol; Yoshioka, Hayato; Shinno, Hidenori; Egusa, Hiroshi. Titanium Nanosurface with a Biomimetic Physical Microenvironment to Induce Endogenous Regeneration of the Periodontium. Acs Applied Materials & Interfaces. 2022;14(24):27703-27719.  PubMed
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Nagayama, Kazuaki. A Loss of Nuclear-Cytoskeletal Interactions in Vascular Smooth Muscle Cell Differentiation Induced by a Micro-Grooved Collagen Substrate Enabling the Modeling of an In Vivo Cell Arrangement. Bioengineering (Basel, Switzerland). 2021;8(9)  PubMed
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Nie, Minghao; Shima, Ai; Fukushima, Kenta; Morimoto, Yuya; Takeuchi, Shoji. A Cylindrical Molding Method for the Biofabrication of Plane-Shaped Skeletal Muscle Tissue. Micromachines. 2021;12(11)  PubMed
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Song, Qin; Iku, Shouhei; Sammons, Rachel; Yagami, Kimitoshi; Furusawa, Toshitake; Morimoto, Koichi; Rahaman, Md Shiblur; Kurasaki, Masaaki; Tokura, Seiichi; Kuboki, Yoshinori. Binding of collagen gene products with titanium oxide. Journal Of Biochemistry. 2021;169(5):565-573.  PubMed
- Comments: I-AC fabricating/coating scaffold
Utoh, Rie; Enomoto, Sakiko; Yamada, Masumi; Yamanaka, Keigo; Yajima, Yuya; Furusawa, Kazuya; Seki, Minoru. Polyanion-induced, microfluidic engineering of fragmented collagen microfibers for reconstituting extracellular environments of 3D hepatocyte culture. Materials Science & Engineering. C, Materials For Biological Applications. 2021;129( 34579926):112417.  PubMed
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Varma, Ratna; Marin-Araujo, Alba E; Rostami, Sara; Waddell, Thomas K; Karoubi, Golnaz; Haykal, Siba. Short-Term Preclinical Application of Functional Human Induced Pluripotent Stem Cell-Derived Airway Epithelial Patches. Advanced Healthcare Materials. 2021;10(21):e2100957.  PubMed
- Comments: I-AC fabricating/coating scaffold
Zemmyo, Daiki; Yamamoto, Masashi; Miyata, Shogo. Efficient Decellularization by Application of Moderate High Hydrostatic Pressure with Supercooling Pretreatment. Micromachines. 2021;12(12)  PubMed
- Comments: I-AC fabricating/coating scaffold
Chen, Yazhou; Lee, Kyubae; Yang, Yingnan; Kawazoe, Naoki; Chen, Guoping. PLGA-collagen-ECM hybrid meshes mimicking stepwise osteogenesis and their influence on the osteogenic differentiation of hMSCs. Biofabrication. 2020;12(2):025027.  PubMed
- Comments: I-AC fabricating/coating scaffold
Itai, Shun; Suzuki, Karin; Kurashina, Yuta; Kimura, Hiroo; Amemiya, Tsuyoshi; Sato, Kazuki; Nakamura, Masaya; Onoe, Hiroaki. Cell-encapsulated chitosan-collagen hydrogel hybrid nerve guidance conduit for peripheral nerve regeneration. Biomedical Microdevices. 2020;22(4):81.  PubMed
- Comments: I-AC fabricating/coating scaffold
Nikolaev, Mikhail; Mitrofanova, Olga; Broguiere, Nicolas; Geraldo, Sara; Dutta, Devanjali; Tabata, Yoji; Elci, Bilge; Brandenberg, Nathalie; Kolotuev, Irina; Gjorevski, Nikolce; Clevers, Hans; Lutolf, Matthias P. Homeostatic mini-intestines through scaffold-guided organoid morphogenesis. Nature. 2020;585(7826):574-578.  PubMed
- Comments: I-AC fabricating/coating scaffold
Duong, Van Thuy; Dang, Thi Thao; Hwang, Chang Ho; Back, Sung Hoon; Koo, Kyo-In. Coaxial printing of double-layered and free-standing blood vessel analogues without ultraviolet illumination for high-volume vascularised tissue. Biofabrication. 2020;12(4):045033.  PubMed
- Comments: I-AC fabricating/coating scaffold
Nie, Minghao; Nagata, Shogo; Aoyagi, Hoshimi; Itou, Akane; Shima, Ai; Takeuchi, Shoji. Cell-laden microfibers fabricated using μl cell-suspension. Biofabrication. 2020;12(4):045021.  PubMed
- Comments: I-AC fabricating/coating scaffold
Shima, Ai; Itou, Akane; Takeuchi, Shoji. Cell fibers promote proliferation of co-cultured cells on a dish. Scientific Reports. 2020;10(1):288.  PubMed
- Comments: I-AC fabricating/coating scaffold
Uzu, Miaki; Takezawa, Toshiaki. Novel microvascular endothelial model utilizing a collagen vitrigel membrane and its advantages for predicting histamine-induced microvascular hyperpermeability. Journal Of Pharmacological And Toxicological Methods. 2020;106( 32890732):106916.  PubMed
- Comments: I-AC fabricating/coating scaffold
Watanabe, Takaichi; Okitsu, Teru; Ozawa, Fumisato; Nagata, Shogo; Matsunari, Hitomi; Nagashima, Hiroshi; Nagaya, Masaki; Teramae, Hiroki; Takeuchi, Shoji. Millimeter-thick xenoislet-laden fibers as retrievable transplants mitigate foreign body reactions for long-term glycemic control in diabetic mice. Biomaterials. 2020;255( 32562943):120162.  PubMed
- Comments: I-AC fabricating/coating scaffold
Ikeda, Kazuhiro; Takeuchi, Shoji. Anchorage-dependent cell expansion in fiber-shaped microcarrier aggregates. Biotechnology Progress. 2019;35(2):e2755.  PubMed
- Comments: I-AC fabricating/coating scaffold
Kurashina, Yuta; Sato, Ryo; Onoe, Hiroaki. Microfiber-shaped building-block tissues with endothelial networks for constructing macroscopic tissue assembly. Apl Bioengineering. 2019;3(4):046101.  PubMed
- Comments: I-AC fabricating/coating scaffold


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