HLA-A*02:01 p53 Tetramer-LLGRNSFEV-PE

MBL Life Sciences

Catalog No.: MBL-TS-M081-1

The α3 mutation significantly reduces the binding of MHC tetramer to human CD8. To minimizes the aberrant effect of some CD8 antibodies; clone SFCI21Thy2D3 (also known as “T8”) is recommended.

Product Specifications

• Application: FC
• Reactivity: Human
• Conjugation: PE
• Immunogen: p53
• Peptide Sequence: LLGRNSFEV
• Class: Class I
• Sequence Location: 264-272
• MHC Allele: A*02:01

Citations for HLA-A*02:01 p53 Tetramer-LLGRNSFEV-PE – 1 Found

Li, Zhi-Ling; Zhang, Hai-Liang; Huang, Yun; Huang, Jun-Hao; Sun, Peng; Zhou, Ning-Ning; Chen, Yu-Hong; Mai, Jia; Wang, Yan; Yu, Yan; Zhou, Li-Huan; Li, Xuan; Yang, Dong; Peng, Xiao-Dan; Feng, Gong-Kan; Tang, Jun; Zhu, Xiao-Feng; Deng, Rong. Autophagy deficiency promotes triple-negative breast cancer resistance to T cell-mediated cytotoxicity by blocking tenascin-C degradation. Nature Communications. 2020;11(1):3806. 
- Comments: Used in: FCM