High Sensitivity CPD/Cyclobutane Pyrimidine Dimer ELISA kit Ver.3

Cosmo Bio

Catalog No.: CSR-NM-MA-K003V3

Product Description

This High Sensitivity Cyclobutane Pyrimidine Dimers (CPDs) ELISA Kit is the only commercially available ELISA utilizing anti-CPDs clone TDM-2 and has been optimized for high sensitivity detection of CPDs in DNA purified from cultured cells or from skin epidermis. This ELISA detects CPDs from dipyrimidines in all DNA sequence contexts (i.e., TT, TC, CT and CC). Thus, the availability and convenience of this ELISA Kit will contribute to further understanding molecular mechanisms involved in cellular responses to UV radiation and DNA damage with applications across many research fields including cancer research, photobiology, dermatology, ophthalmology, immunology, and cosmetics science.

Citations for High Sensitivity CPD/Cyclobutane Pyrimidine Dimer ELISA kit Ver.3 – 9 Found

Yamashita, Michiyo; Aihara, Mutsumi; Onoda, Yushi; Fukushima, Shiho; Nagahashi, Miharu; Aizawa, Toshihiko; Yamauchi, Shigeharu; Fujikawa, Yasuo; Tanaka, Tomotake; Kadomura-Ishikawa, Yasuko; Ishida, Kai; Matsubara, Mina; Uebanso, Takashi; Mawatari, Kazuaki; Takahashi, Akira. Wavelength-dependent differences in survival of Cladosporium sphaerospermum exposed to ultraviolet light. The Journal Of Medical Investigation : Jmi. 72(3.4):260-265. 

Zhou, Shuyan; Zhang, Yi; Li, Zongzhu; Li, Zhuqing; Latham, Patricia S; Meng, Yunxiao; Chen, Wen; Yang, Penghua; Hou, Chunyan; Ma, Junfeng; Zhu, Wenge. And-1 coordinates with polymerase δ to regulate nucleotide excision repair and UVB-induced skin tumorigenesis. Nature Communications. 2025;16(1):9313. 

Yu, Lei; Xu, Si-Yuan; Luo, Xin-Cheng; Ying, Sheng-Hua; Feng, Ming-Guang. Rad1 and Rad10 Tied to Photolyase Regulators Protect Insecticidal Fungal Cells from Solar UV Damage by Photoreactivation. Journal Of Fungi (Basel, Switzerland). 2022;8(11) 

Fukui, Tomoaki; Niikura, Takahiro; Oda, Takahiro; Kumabe, Yohei; Ohashi, Hiroyuki; Sasaki, Masahiro; Igarashi, Tatsushi; Kunisada, Makoto; Yamano, Nozomi; Oe, Keisuke; Matsumoto, Tomoyuki; Matsushita, Takehiko; Hayashi, Shinya; Nishigori, Chikako; Kuroda, Ryosuke. Exploratory clinical trial on the safety and bactericidal effect of 222-nm ultraviolet C irradiation in healthy humans. Plos One. 15(8):e0235948. 

Li, Han; Li, Dong; Yang, Zhen; Zeng, Qiwei; Luo, Yiwei; He, Ningjia. Flavones Produced by Mulberry Flavone Synthase Type I Constitute a Defense Line against the Ultraviolet-B Stress. Plants (Basel, Switzerland). 2020;9(2) 

Steurer, Barbara; Turkyilmaz, Yasemin; van Toorn, Marvin; van Leeuwen, Wessel; Escudero-Ferruz, Paula; Marteijn, Jurgen A. Fluorescently-labelled CPD and 6-4PP photolyases: new tools for live-cell DNA damage quantification and laser-assisted repair. Nucleic Acids Research. 2019;47(7):3536-3549. 

Wang, Ding-Yi; Fu, Bo; Tong, Sen-Miao; Ying, Sheng-Hua; Feng, Ming-Guang. Two Photolyases Repair Distinct DNA Lesions and Reactivate UVB-Inactivated Conidia of an Insect Mycopathogen under Visible Light. Applied And Environmental Microbiology. 2019;85(4) 

Lopez Perez, Ramon; Brauer, Jannek; Rühle, Alexander; Trinh, Thuy; Sisombath, Sonevisay; Wuchter, Patrick; Grosu, Anca-Ligia; Debus, Jürgen; Saffrich, Rainer; Huber, Peter E; Nicolay, Nils H. Human mesenchymal stem cells are resistant to UV-B irradiation. Scientific Reports. 2019;9(1):20000. 

Perez-Oliva, Ana B; Lachaud, Christophe; Szyniarowski, Piotr; Muñoz, Ivan; Macartney, Thomas; Hickson, Ian; Rouse, John; Alessi, Dario R. USP45 deubiquitylase controls ERCC1-XPF endonuclease-mediated DNA damage responses. The Embo Journal. 2015;34(3):326-43.