Fluoresceinamine Labeled Sodium Dermatan Sulfate (B1, Porcine Skin)

Cosmo Bio

Catalog No.: CSR-FADS-B1(PGS)3

useful for research of chondroitin sulfate Dermatan sulfate (DS) is a sulfated glycosaminoglycan composed of repeating disaccharide units of N-acetyl-D-galactosamine (GalNAc) and D-glucuronic acid (GlcUA) or D-iduronic acid (IdoUA). DS is abundant in skin and exists as unbranched polysaccharide chains covalently linked to the protein core of proteoglycans. This product is prepared by the fluorescent labeling of DS derived from porcine skin according to the method of Ogamo et.al.1). Fluoresceinamine molecules are chemicallyattached to carboxyl groups of the GlcUA or IdoUA of DS. FADS-B1 contains approximately 80 % of disaccharide units with one sulfate groups as 4-O-sulfation of GalNAc. This solution is dissolved in PBS (-) and sterilized by filtration. The endotoxin content is in accordance with the product specifications. The excitation wavelength is 490~500 nm and the emission wavelength is 515~525 nm. The enclosed Certification of Analysis lists actual values for product specifications.