Arginase Activity Assay Kit

Cosmo Bio

Catalog No.: PMC-AK89N

Product Description

Arginase is an enzyme that hydrolyzes L-Arginine to L-Ornithine and urea. It is known to be strongly expressed when macrophages are activated in M2 of the M1 (inflammatory)/M2 (non-inflammatory) known as one of the functional classifications of macrophages and is frequently used as a marker of M2 macrophage activation. This product extracts intracellular arginase and evaluates arginase activity by detecting urea produced by arginase from L-arginine. Compared to conventional assay methods, the stability and sensitivity of the reagent have been improved, and arginase activity can be easily measured. This product is based on a patent owned by Professor Yasuhiko Tabata of Kyoto University and TOKYO OHKA KOGYO CO., LTD.

Citations for Arginase Activity Assay Kit – 4 Found

Miki, Tsuyoshi; Uemura, Takeshi; Kinoshita, Miki; Ami, Yuta; Ito, Masahiro; Okada, Nobuhiko; Furuchi, Takemitsu; Kurihara, Shin; Haneda, Takeshi; Minamino, Tohru; Kim, Yun-Gi. Salmonella Typhimurium exploits host polyamines for assembly of the type 3 secretion machinery. Plos Biology. 2024;22(8):e3002731. 

Yamaguchi, Yasuno; Uchimura, Kohei; Takahashi, Kazuya; Ishii, Toshihisa; Hanai, Shunichiro; Furuya, Fumihiko. Hyperthyroidism exacerbates ischemic reperfusion injury in the kidney. Endocrine Journal. 2022;69(3):263-272. 

Ishitobi, Kazunari; Kotani, Hitoshi; Iida, Yuichi; Taniura, Takahito; Notsu, Yoshitomo; Tajima, Yoshitsugu; Harada, Mamoru. A modulatory effect of L-arginine supplementation on anticancer effects of chemoimmunotherapy in colon cancer-bearing aged mice. International Immunopharmacology. 2022;113(Pt A):109423. 

Nagai, Motoyoshi; Okawa, Takuma; Nakata, Kazuaki; Takahashi, Daisuke; Miyajima, Reina; Shiratori, Hiroaki; Yamanaka, Daisuke; Nakamura, Atsuo; Oyama, Chinatsu; Takahashi, Shin-Ichiro; Toyama-Sorimachi, Noriko; Suzuki, Koichiro; Ohashi, Wakana; Dohi, Taeko; Kawamura, Yuki I; Hase, Koji. Sugar and arginine facilitate oral tolerance by ensuring the functionality of tolerogenic immune cell subsets in the intestine. Cell Reports. 2024;43(7):114490.