Anti TLR7 mAb (Clone 6E5)

CUSABIO

SKU:
CSB-RA556665A0HU-50
  • IHC image of CSB-RA556665A0HU diluted at 1:100 and staining in paraffin-embedded human tonsil tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
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Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).

Product Specifications
Application IHC, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 600000)


Documents & Links for Anti TLR7 mAb (Clone 6E5)
Datasheet Anti TLR7 mAb (Clone 6E5) Datasheet

Documents & Links for Anti TLR7 mAb (Clone 6E5)
Datasheet Anti TLR7 mAb (Clone 6E5) Datasheet



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