Anti SPAG6 pAb (ATL-HPA038440 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA038440-25

Protein Description: sperm associated antigen 6
Gene Name: SPAG6
Alternative Gene Name: CT141, pf16, Repro-SA-1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000022783: 92%, ENSRNOG00000025787: 92%
Entrez Gene ID: 9576
Uniprot ID: O75602
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: AVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEA
• Gene Sequence: AVPLLVLCIQEPEIALKRIAASALSDIAKHSPELAQTVVDAGAVAHLAQMILNPDAKLKHQILSALSQVSKHSVDLAEMVVEA
• Gene ID - Mouse: ENSMUSG00000022783
• Gene ID - Rat: ENSRNOG00000025787
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti SPAG6 pAb (ATL-HPA038440 w/enhanced validation) – 13 Found

Djureinovic, Dijana; Hallström, Björn M; Horie, Masafumi; Mattsson, Johanna Sofia Margareta; La Fleur, Linnea; Fagerberg, Linn; Brunnström, Hans; Lindskog, Cecilia; Madjar, Katrin; Rahnenführer, Jörg; Ekman, Simon; Ståhle, Elisabeth; Koyi, Hirsh; Brandén, Eva; Edlund, Karolina; Hengstler, Jan G; Lambe, Mats; Saito, Akira; Botling, Johan; Pontén, Fredrik; Uhlén, Mathias; Micke, Patrick. Profiling cancer testis antigens in non-small-cell lung cancer. Jci Insight. 2016;1(10):e86837. 

Altenberger, Corinna; Heller, Gerwin; Ziegler, Barbara; Tomasich, Erwin; Marhold, Maximilian; Topakian, Thais; Müllauer, Leonhard; Heffeter, Petra; Lang, György; End-Pfützenreuter, Adelheid; Döme, Balazs; Arns, Britt-Madeleine; Klepetko, Walter; Zielinski, Christoph C; Zöchbauer-Müller, Sabine. SPAG6 and L1TD1 are transcriptionally regulated by DNA methylation in non-small cell lung cancers. Molecular Cancer. 2017;16(1):1. 

Tu, Chaofeng; Cong, Jiangshan; Zhang, Qianjun; He, Xiaojin; Zheng, Rui; Yang, Xiaoxuan; Gao, Yang; Wu, Huan; Lv, Mingrong; Gu, Yayun; Lu, Shuai; Liu, Chunyu; Tian, Shixiong; Meng, Lanlan; Wang, Weili; Tan, Chen; Nie, Hongchuan; Li, Dongyan; Zhang, Huan; Gong, Fei; Hu, Liang; Lu, Guangxiu; Xu, Wenming; Lin, Ge; Zhang, Feng; Cao, Yunxia; Tan, Yue-Qiu. Bi-allelic mutations of DNAH10 cause primary male infertility with asthenoteratozoospermia in humans and mice. American Journal Of Human Genetics. 2021;108(8):1466-1477. 

Xu, Chuan; Tang, Dongdong; Shao, Zhongmei; Geng, Hao; Gao, Yang; Li, Kuokuo; Tan, Qing; Wang, Guanxiong; Wang, Chao; Wu, Huan; Li, Guanjian; Lv, Mingrong; He, Xiaojin; Cao, Yunxia. Homozygous SPAG6 variants can induce nonsyndromic asthenoteratozoospermia with severe MMAF. Reproductive Biology And Endocrinology : Rb&E. 2022;20(1):41. 

Dong, Frederick N; Amiri-Yekta, Amir; Martinez, Guillaume; Saut, Antoine; Tek, Julie; Stouvenel, Laurence; Lorès, Patrick; Karaouzène, Thomas; Thierry-Mieg, Nicolas; Satre, Véronique; Brouillet, Sophie; Daneshipour, Abbas; Hosseini, Seyedeh Hanieh; Bonhivers, Mélanie; Gourabi, Hamid; Dulioust, Emmanuel; Arnoult, Christophe; Touré, Aminata; Ray, Pierre F; Zhao, Haiqing; Coutton, Charles. Absence of CFAP69 Causes Male Infertility due to Multiple Morphological Abnormalities of the Flagella in Human and Mouse. American Journal Of Human Genetics. 2018;102(4):636-648. 

Tu, Chaofeng; Nie, Hongchuan; Meng, Lanlan; Yuan, Shimin; He, Wenbin; Luo, Aixiang; Li, Haiyu; Li, Wen; Du, Juan; Lu, Guangxiu; Lin, Ge; Tan, Yue-Qiu. Identification of DNAH6 mutations in infertile men with multiple morphological abnormalities of the sperm flagella. Scientific Reports. 2019;9(1):15864. 

Liu, Zhen; Nguyen, Quynh P H; Guan, Qingxu; Albulescu, Alexandra; Erdman, Lauren; Mahdaviyeh, Yasaman; Kang, Jasmine; Ouyang, Hong; Hegele, Richard G; Moraes, Theo; Goldenberg, Anna; Dell, Sharon D; Mennella, Vito. A quantitative super-resolution imaging toolbox for diagnosis of motile ciliopathies. Science Translational Medicine. 2020;12(535) 

Zhang, Meng; Luo, Jie; Luo, Xiaohua; Liu, Lin. SPAG6 silencing induces autophagic cell death in SKM-1 cells via the AMPK/mTOR/ULK1 signaling pathway. Oncology Letters. 2020;20(1):551-560. 

He, Xiaojin; Liu, Chunyu; Yang, Xiaoyu; Lv, Mingrong; Ni, Xiaoqing; Li, Qiang; Cheng, Huiru; Liu, Wangjie; Tian, Shixiong; Wu, Huan; Gao, Yang; Yang, Chenyu; Tan, Qing; Cong, Jiangshan; Tang, Dongdong; Zhang, Jingjing; Song, Bing; Zhong, Yading; Li, Hang; Zhi, Weiwei; Mao, Xiaohong; Fu, Feifei; Ge, Lei; Shen, Qunshan; Zhang, Manyu; Saiyin, Hexige; Jin, Li; Xu, Yuping; Zhou, Ping; Wei, Zhaolian; Zhang, Feng; Cao, Yunxia. Bi-allelic Loss-of-function Variants in CFAP58 Cause Flagellar Axoneme and Mitochondrial Sheath Defects and Asthenoteratozoospermia in Humans and Mice. American Journal Of Human Genetics. 2020;107(3):514-526. 

Tan, Chen; Meng, Lanlan; Lv, Mingrong; He, Xiaojin; Sha, Yanwei; Tang, Dongdong; Tan, Yaqi; Hu, Tongyao; He, Wenbin; Tu, Chaofeng; Nie, Hongchuan; Zhang, Huan; Du, Juan; Lu, Guangxiu; Fan, Li-Qing; Cao, Yunxia; Lin, Ge; Tan, Yue-Qiu. Bi-allelic variants in DNHD1 cause flagellar axoneme defects and asthenoteratozoospermia in humans and mice. American Journal Of Human Genetics. 2022;109(1):157-171. 

Li, Kuokuo; Wang, Guanxiong; Lv, Mingrong; Wang, Jieyu; Gao, Yang; Tang, Fei; Xu, Chuan; Yang, Wen; Yu, Hui; Shao, Zhongmei; Geng, Hao; Tan, Qing; Shen, Qunshan; Tang, Dongdong; Ni, Xiaoqing; Wang, Tianjuan; Song, Bing; Wu, Huan; Huo, Ran; Zhang, Zhiguo; Xu, Yuping; Zhou, Ping; Tao, Fangbiao; Wei, Zhaolian; He, Xiaojin; Cao, Yunxia. Bi-allelic variants in DNAH10 cause asthenoteratozoospermia and male infertility. Journal Of Assisted Reproduction And Genetics. 2022;39(1):251-259. 

Lv, Mingrong; Tang, Dongdong; Yu, Hui; Geng, Hao; Zhou, Yiling; Shao, Zhongmei; Li, Kuokuo; Gao, Yang; Guo, Senchao; Xu, Chuan; Tan, Qing; Liu, Chunyu; Guo, Rui; Wu, Huan; Duan, Zongliu; Zhang, Jingjing; Wang, Guanxiong; Hua, Rong; Fu, Feifei; Wang, Kai; Xu, Yuping; Zhou, Ping; Wei, Zhaolian; Zhang, Feng; Cao, Yunxia; He, Xiaojin. Novel FSIP2 Variants Induce Super-Length Mitochondrial Sheath and Asthenoteratozoospermia in Humans. International Journal Of Biological Sciences. 19(2):393-411. 

Yu, Hui; Shi, Xiao; Shao, Zhongmei; Geng, Hao; Guo, Senzhao; Li, Kuokuo; Gu, Meng; Xu, Chuan; Gao, Yang; Tan, Qing; Duan, Zongliu; Wu, Huan; Hua, Rong; Guo, Rui; Wei, Zhaolian; Zhou, Ping; Cao, Yunxia; He, Xiaojin; Li, Liang; Zhang, Xiaoping; Lv, Mingrong. Novel HYDIN variants associated with male infertility in two Chinese families. Frontiers In Endocrinology. 14( 36742411):1118841.