Anti SOX2 mAb (Clone 2E1)

CUSABIO

Catalog No.:
CSB-RA973770A0HU-50
Western Blot<br /> Positive WB detected in: U-251 whole cell lysate, MCF-7 whole cell lysate, Mouse Brain whole cell lysate, Rat Brain whole cell lysate<br /> All lanes: SOX2 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 35 kDa<br /> Observed band size: 40 kDa<br />
IHC image of CSB-RA973770A0HU diluted at 1:100 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
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Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).

Product Specifications
Application WB, IHC, ELISA
Reactivity Human, Mouse, Rat
Clonality Monoclonal (Clone No.: 20)

Documents & Links for Anti SOX2 mAb (Clone 2E1)
Datasheet Anti SOX2 mAb (Clone 2E1) Datasheet

Documents & Links for Anti SOX2 mAb (Clone 2E1)
Datasheet Anti SOX2 mAb (Clone 2E1) Datasheet
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