Anti Calcineurin B-Like Protein 4 (CBL4/SOS3) pAb (Rabbit, Antiserum)

Cosmo Bio LTD

Catalog No: CAC-KYU-TY-P02

Catalog numbers beginning with "CAC" are antibodies from our exclusive Cosmo Bio Antibody Collection. Visit the CAC Antibody homepage to browse the collection list, organized by research topic.

Application: IP, WB 
Clonality: Polyclonal 
Host: Rabbit 
Purification: Serum 
Reactivity: Plant, Tomato, Soybean, Cowpea 

Application of the Arabidopsis model system has yielded a regulatory pathway for ionic homeostasis under salt stress. The pathway was discovered through the cloning of the salt overly sensitive (SOS) genes. Mutations in the SOS genes render Arabidopsis plants more sensitive to Na+ stress. The pathway begins with SOS3, a myristoylated protein with three EF hands for calcium binding. SOS3 interacts physically with SOS2, which is a serine/threonine protein kinase. One downstream target of SOS3–SOS2 kinase complex is SOS1, which is a plasma membrane Na+–H+ antiporter that exports Na+ from the cell. SOS1 expression is upregulated by salt stress in wild-type Arabidopsis plants but this upregulation is reduced by sos3 or sos2 mutations. It remains to be seen whether or not SOS3–SOS2 directly regulates the activities of SOS1 and other transporter through phosphorylation. Remaining components in the SOS pathway are expected to be identified by cloning additional SOS genes and screening for second site suppressor and enhancer mutations in the sos mutant backgrounds. [from: Zhu JK. (2001) Plant salt tolerance. TRENDS in Plant Science. 6(2):66-71]

References:
1) Yuasa T, Ishibashi Y. and Iwaya-Inoue M. (2012) A flower specific calcineurin B-like molecule (CBL)-interacting protein kinase (CIPK) homolog in tomato cultivar Micro-Tom (Solanum lycopersicum L.). American Journal of Plant Sciences. 3:753-763.
2) Imamura M, Yuasa T, Takahashi T, Nakamura N, Nang MPSH, Zheng SH, Shimazaki K. and Iwaya-Inoue M. (2008) Isolation and characterization of a cDNA coding cowpea (Vigna unguiculata (L.) Walp.) calcineurin B-like protein interacting protein kinase, VuCIPK1. Plant Biotechnol. 25:437-445.