Anti SF-1 mAb (Clone N1665)

Cosmo Bio LTD

Catalog No: PPX-PP-N1665-0C

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Application: IP, ELISA, IHC, WB 
Clonality: Monoclonal 
Host: Mouse 
Purification: Purified 
Reactivity: Mouse, Rat, Human 

SF-1 (AD4BP, FTZF1,NR5A1) is still considered as an orphan nuclear receptor belongs to subfamily 5, It was found as a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as ligands. Its expressed in all sterodogenic tissues, including adrenal cortex, testicular Sertoli cells and Leydig cells, ovarian theca, hypothalamus and anterior pituitary. SF1 plays an important role in adrenal and gonadal development, such as hypothalamic-pituitary-gonadal axis and sex determination.