Anti RPE65 mAb (Clone 7B10)

CUSABIO

Catalog No.:
CSB-RA212530A0HU-50
IHC image of CSB-RA212530A0HU diluted at 1:100 and staining in paraffin-embedded human eye tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
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Plays important roles in the production of 11-cis retinal and in visual pigment regeneration. The soluble form binds vitamin A (all-trans-retinol), making it available for LRAT processing to all-trans-retinyl ester. The membrane form, palmitoylated by LRAT, binds all-trans-retinyl esters, making them available for IMH (isomerohydrolase) processing to all-cis-retinol. The soluble form is regenerated by transferring its palmitoyl groups onto 11-cis-retinol, a reaction catalyzed by LRAT. The enzymatic activity is linearly dependent of the expression levels and membrane association.

Product Specifications
Application IHC, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 7B10)

Documents & Links for Anti RPE65 mAb (Clone 7B10)
Datasheet Anti RPE65 mAb (Clone 7B10) Datasheet

Documents & Links for Anti RPE65 mAb (Clone 7B10)
Datasheet Anti RPE65 mAb (Clone 7B10) Datasheet
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