Anti PTPN11 mAb (Clone 7A1)

CUSABIO

Catalog No.:
CSB-RA779218A0HU-50
Western Blot<br /> Positive WB detected in: Jurkat whole cell lysate, 293 whole cell lysate, MCF-7 whole cell lysate, Hela whole cell lysate, K562 whole cell lysate<br /> All lanes: PTPN11 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 69, 53 kDa<br /> Observed band size: 69 kDa<br />
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Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).

Product Specifications
Application WB, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 7A1)

Documents & Links for Anti PTPN11 mAb (Clone 7A1)
Datasheet Anti PTPN11 mAb (Clone 7A1) Datasheet

Documents & Links for Anti PTPN11 mAb (Clone 7A1)
Datasheet Anti PTPN11 mAb (Clone 7A1) Datasheet
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