Anti PTPN11 mAb (Clone 6G11)

CUSABIO

Catalog No.:
CSB-RA289762A0HU-50
Western Blot<br /> Positive WB detected in: Jurkat whole cell lysate, 293 whole cell lysate, MCF-7 whole cell lysate, Hela whole cell lysate, K562 whole cell lysate, HL60 whole cell lysate<br /> All lanes: PTPN11 antibody at 1:2000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 69, 53 kDa<br /> Observed band size: 69 kDa<br />
IHC image of CSB-RA289762A0HU diluted at 1:100 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Shipping:
Calculated at Checkout
$221.00
Adding to cart… The item has been added
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).

Product Specifications
Application WB, IHC, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 6G11)

Documents & Links for Anti PTPN11 mAb (Clone 6G11)
Datasheet Anti PTPN11 mAb (Clone 6G11) Datasheet

Documents & Links for Anti PTPN11 mAb (Clone 6G11)
Datasheet Anti PTPN11 mAb (Clone 6G11) Datasheet
!