Anti PTGS2 mAb (Clone 10B2)

CUSABIO

Catalog No.:
CSB-RA920283A0HU-50
Western Blot<br /> Positive WB detected in: U-87 whole cell lysate<br /> All lanes: COX2 Antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 69 kDa<br /> Observed band size: 69 kDa<br />
Immunofluorescence staining of HepG2 Cells with CSB-RA920283A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
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Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays important roles in modulating motility, proliferation and resistance to apoptosis.

Product Specifications
Application WB, IF, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 10B2)

Documents & Links for Anti PTGS2 mAb (Clone 10B2)
Datasheet Anti PTGS2 mAb (Clone 10B2) Datasheet

Documents & Links for Anti PTGS2 mAb (Clone 10B2)
Datasheet Anti PTGS2 mAb (Clone 10B2) Datasheet
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