Application: WB, IHC, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
| Documents & Links for Anti PTBP1 mAb (Clone 8A1) | |
| Datasheet | Anti PTBP1 mAb (Clone 8A1) Datasheet |
| Vendor Page | Anti PTBP1 mAb (Clone 8A1) at CUSABIO |
| Documents & Links for Anti PTBP1 mAb (Clone 8A1) | |
| Datasheet | Anti PTBP1 mAb (Clone 8A1) Datasheet |
| Vendor Page | Anti PTBP1 mAb (Clone 8A1) |
