Anti PICALM pAb (ATL-HPA019061 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA019061-25

Protein Description: phosphatidylinositol binding clathrin assembly protein
Gene Name: PICALM
Alternative Gene Name: CALM, CLTH
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000039361: 100%, ENSRNOG00000018322: 100%
Entrez Gene ID: 8301
Uniprot ID: Q13492
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, IHC
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: DIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRL
• Gene Sequence: DIPDLSQAPSSLLDALEQHLASLEGKKIKDSTAASRATTLSNAVSSLASTGLSLTKVDEREKQAALEEEQARLKALKEQRL
• Gene ID - Mouse: ENSMUSG00000039361
• Gene ID - Rat: ENSRNOG00000018322
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti PICALM pAb (ATL-HPA019061 w/enhanced validation) – 3 Found

Huynh, Van N; Benavides, Gloria A; Johnson, Michelle S; Ouyang, Xiaosen; Chacko, Balu K; Osuma, Edie; Mueller, Toni; Chatham, John; Darley-Usmar, Victor M; Zhang, Jianhua. Acute inhibition of OGA sex-dependently alters the networks associated with bioenergetics, autophagy, and neurodegeneration. Molecular Brain. 2022;15(1):22. 

Mercer, Jacob L; Argus, Joseph P; Crabtree, Donna M; Keenan, Melissa M; Wilks, Moses Q; Chi, Jen-Tsan Ashley; Bensinger, Steven J; Lavau, Catherine P; Wechsler, Daniel S. Modulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis. Plos One. 10(6):e0129776. 

Azarnia Tehran, Domenico; Kochlamazashvili, Gaga; Pampaloni, Niccolò P; Sposini, Silvia; Shergill, Jasmeet Kaur; Lehmann, Martin; Pashkova, Natalya; Schmidt, Claudia; Löwe, Delia; Napieczynska, Hanna; Heuser, Arnd; Plested, Andrew J R; Perrais, David; Piper, Robert C; Haucke, Volker; Maritzen, Tanja. Selective endocytosis of Ca(2+)-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity. Science Advances. 2022;8(21):eabl5032.