Anti Phospho-SMC1A (S957) mAb (Clone 1F9)

CUSABIO

SKU:
CSB-RA614804A957phHU-50
  • Western Blot<br />
Positive WB detected in 293 whole cell lysate(treated with Calyculin A or not)<br />
All lanes Phospho-SMC1A antibody at 1.11μg/ml<br />
Secondary<br />
Goat polyclonal to rabbit IgG at 1/50000 dilution<br />
Predicted band size: 160 KDa<br />
Observed band size: 160 KDa<br />
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$221.00
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Involved in chromosome cohesion during cell cycle and in DNA repair. Central component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The cohesin complex may also play a role in spindle pole assembly during mitosis. Involved in DNA repair via its interaction with BRCA1 and its related phosphorylation by ATM, or via its phosphorylation by ATR. Works as a downstream effector both in the ATM/NBS1 branch and in the ATR/MSH2 branch of S-phase checkpoint.

Product Specifications
Application WB, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 1F9)


Documents & Links for Anti Phospho-SMC1A (S957) mAb (Clone 1F9)
Datasheet Anti Phospho-SMC1A (S957) mAb (Clone 1F9) Datasheet

Documents & Links for Anti Phospho-SMC1A (S957) mAb (Clone 1F9)
Datasheet Anti Phospho-SMC1A (S957) mAb (Clone 1F9) Datasheet