Application: WB, IP, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human
Acts downstream of various receptor and cytoplasmic protein tyrosine kinases to participate in the signal transduction from the cell surface to the nucleus. Positively regulates MAPK signal transduction pathway (PubMed:28074573). Dephosphorylates GAB1, ARHGAP35 and EGFR (PubMed:28074573). Dephosphorylates ROCK2 at 'Tyr-722' resulting in stimulatation of its RhoA binding activity. Dephosphorylates CDC73 (PubMed:26742426).
| Documents & Links for Anti Phospho-PTPN11 (Y542) mAb (Clone 2E2) | |
| Datasheet | Anti Phospho-PTPN11 (Y542) mAb (Clone 2E2) Datasheet |
| Vendor Page | Anti Phospho-PTPN11 (Y542) mAb (Clone 2E2) at CUSABIO |
| Documents & Links for Anti Phospho-PTPN11 (Y542) mAb (Clone 2E2) | |
| Datasheet | Anti Phospho-PTPN11 (Y542) mAb (Clone 2E2) Datasheet |
| Vendor Page | Anti Phospho-PTPN11 (Y542) mAb (Clone 2E2) |