Anti Phospho-MLKL (S358) mAb (Clone 4A6)

CUSABIO

Catalog No.:
CSB-RA850851A358phHU-50
IHC image of CSB-RA850851A358phHU diluted at 1:100 and staining in paraffin-embedded human melanoma cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

Product Specifications
Application IHC, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 4A6)

Documents & Links for Anti Phospho-MLKL (S358) mAb (Clone 4A6)
Datasheet Anti Phospho-MLKL (S358) mAb (Clone 4A6) Datasheet

Documents & Links for Anti Phospho-MLKL (S358) mAb (Clone 4A6)
Datasheet Anti Phospho-MLKL (S358) mAb (Clone 4A6) Datasheet
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