Anti Phospho-MAPT (S324) mAb (Clone 4E8)

CUSABIO

Catalog No.:
CSB-RA013481A324phHU-50
Immunofluorescence staining of SH-SY5Y cells with CSB-RA013481A324phHU at 1:100,counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
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Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.

Product Specifications
Application IF, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 400000000)

Documents & Links for Anti Phospho-MAPT (S324) mAb (Clone 4E8)
Datasheet Anti Phospho-MAPT (S324) mAb (Clone 4E8) Datasheet

Documents & Links for Anti Phospho-MAPT (S324) mAb (Clone 4E8)
Datasheet Anti Phospho-MAPT (S324) mAb (Clone 4E8) Datasheet
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