Anti NGF mAb (Clone 5F10)

CUSABIO

Catalog No.:
CSB-RA288635A0HU-50
Western Blot<br /> Positive WB detected in: U-87 whole cell lysate, Rat Brain whole cell lysate<br /> All lanes: NGF antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 27 kDa<br /> Observed band size: 39 kDa<br />
IHC image of CSB-RA288635A0HU diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
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Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Inhibits metalloproteinase dependent proteolysis of platelet glycoprotein VI (PubMed:20164177).

Product Specifications
Application WB, IHC, ELISA
Reactivity Human, Rat
Clonality Monoclonal (Clone No.: 5F10)

Documents & Links for Anti NGF mAb (Clone 5F10)
Datasheet Anti NGF mAb (Clone 5F10) Datasheet

Documents & Links for Anti NGF mAb (Clone 5F10)
Datasheet Anti NGF mAb (Clone 5F10) Datasheet
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