Anti MYO5B pAb (ATL-HPA040902 w/enhanced validation)

Atlas Antibodies

Catalog No.: ATL-HPA040902-25

Protein Description: myosin VB
Gene Name: MYO5B
Alternative Gene Name: KIAA1119
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000025885: 94%, ENSRNOG00000014104: 89%
Entrez Gene ID: 4645
Uniprot ID: Q9ULV0
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: NLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLK
• Gene Sequence: NLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVEEIGLEKAAMDMTVFLK
• Gene ID - Mouse: ENSMUSG00000025885
• Gene ID - Rat: ENSRNOG00000014104
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti MYO5B pAb (ATL-HPA040902 w/enhanced validation) – 5 Found

Cartón-García, Fernando; Overeem, Arend W; Nieto, Rocio; Bazzocco, Sarah; Dopeso, Higinio; Macaya, Irati; Bilic, Josipa; Landolfi, Stefania; Hernandez-Losa, Javier; Schwartz, Simo Jr; Ramon y Cajal, Santiago; van Ijzendoorn, Sven C D; Arango, Diego. Myo5b knockout mice as a model of microvillus inclusion disease. Scientific Reports. 2015;5( 26201991):12312. 

Letellier, Elisabeth; Schmitz, Martine; Ginolhac, Aurélien; Rodriguez, Fabien; Ullmann, Pit; Qureshi-Baig, Komal; Frasquilho, Sonia; Antunes, Laurent; Haan, Serge. Loss of Myosin Vb in colorectal cancer is a strong prognostic factor for disease recurrence. British Journal Of Cancer. 2017;117(11):1689-1701. 

Weis, Victoria G; Knowles, Byron C; Choi, Eunyoung; Goldstein, Anna E; Williams, Janice A; Manning, Elizabeth H; Roland, Joseph T; Lapierre, Lynne A; Goldenring, James R. Loss of MYO5B in mice recapitulates Microvillus Inclusion Disease and reveals an apical trafficking pathway distinct to neonatal duodenum. Cellular And Molecular Gastroenterology And Hepatology. 2016;2(2):131-157. 

Tomić, Tajana Tešan; Olausson, Josefin; Rehammar, Anna; Deland, Lily; Muth, Andreas; Ejeskär, Katarina; Nilsson, Staffan; Kristiansson, Erik; Wassén, Ola Nilsson; Abel, Frida. MYO5B mutations in pheochromocytoma/paraganglioma promote cancer progression. Plos Genetics. 2020;16(6):e1008803. 

Niu, Fengfeng; Sun, Kang; Wei, Wenjie; Yu, Cong; Wei, Zhiyi. F-actin disassembly factor MICAL1 binding to Myosin Va mediates cargo unloading during cytokinesis. Science Advances. 2020;6(45)