Anti MYBBP1A mAb (Clone 3A1)

CUSABIO

SKU:
CSB-RA978157A0HU-50
  • IHC image of CSB-RA978157A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
  • Immunofluorescence staining of HepG2 Cells with CSB-RA978157A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeated by 0.2% TritonX-100, and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. Nuclear DNA was labeled in blue with DAPI. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Rabbit IgG (H+L).
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May activate or repress transcription via interactions with sequence specific DNA-binding proteins. Repression may be mediated at least in part by histone deacetylase activity (HDAC activity). Acts as a corepressor and in concert with CRY1, represses the transcription of the core circadian clock component PER2. Preferentially binds to dimethylated histone H3 'Lys-9' (H3K9me2) on the PER2 promoter.

Product Specifications
Application IHC, IF, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 3A1)


Documents & Links for Anti MYBBP1A mAb (Clone 3A1)
Datasheet Anti MYBBP1A mAb (Clone 3A1) Datasheet

Documents & Links for Anti MYBBP1A mAb (Clone 3A1)
Datasheet Anti MYBBP1A mAb (Clone 3A1) Datasheet