Anti Macrophage Scavenger Receptor 1 (MSR1/CD204) mAb (Clone SRA-E5p6)

Cosmo Bio

Catalog No.: CAC-KMU-MA01A

Product Description

CD204, also referred as macrophage scavenger receptor class A type I/II (MSR-A) or macrophage scavenger receptor type I/II (MSR1), is one of the major receptors of macrophages and plays important roles in many macrophage-related disorders. CD204 binds various negatively charged macromolecules, such as modified low-density lipoproteins, fucoidan, advanced glycation end-products, denatured collagen, and bacterial components.

References:

1) Nature. 1997 Mar 20;386(6622):292-6.
2) Atherosclerosis. 2002 Mar;161(1):123-32. (IHC)
3) J Atheroscler Thromb. 2016;23(1):10-7 (Western blot)
4) Arthritis Res Ther. 2010;12(4):R128. (Flow cytometry)

Clone: ​​SRA-E5p6 is a highly sensitive antibody-producing cell line isolated from Clone: ​​SRA-E5 by recloning.

Product Specifications

• Application: IHC, FC, WB
• Reactivity: Mouse, Rat, Bovine, Monkey, Equine, Porcine, Dog, Cat, Rabbit, Guinea Pig, Hamster
• Clonality: Monoclonal (Clone No.: SRA-E5p6)
• Host: Mouse
• Source: Mammalian

Citations for Anti Macrophage Scavenger Receptor 1 (MSR1/CD204) mAb (Clone SRA-E5p6) – 21 Found

Igase, Masaya; Hagimori, Kenji; Inanaga, Sakuya; Mizoguchi, Hiroki; Itamoto, Kazuhito; Sakurai, Masashi; Motegi, Tomoki; Yamamoto, Hiroka; Kato, Masahiro; Shiga, Toshinori; Tsukui, Toshihiro; Kobayashi, Tetsuya; Mizuno, Takuya. Caninized PD-1 monoclonal antibody in oral malignant melanoma: efficacy and exploratory biomarker analysis. Journal For Immunotherapy Of Cancer. 2026;14(1) 

Okauchi, Nao; Shibutani, Shusaku; Sakurai, Masashi; Yamamoto, Hiroka; Itamoto, Kazuhito; Kato, Daiki; Nakagawa, Takayuki; Maeda, Sadatoshi; Baba, Kenji; Mizuno, Takuya; Igase, Masaya. CXCL8 mediates macrophage migration in canine oral malignant melanoma. Scientific Reports. 2025;15(1):38854. 

Manabe, Maru; Nakamura, Teppei; Sato, Keisuke; Hayashi, Naoki; Kouguchi, Hirokazu; Nakao, Ryo; Hidaka, Masahito; Matsuyama, Hiroyuki; Nonaka, Nariaki; Morimatsu, Masami. Efferocytosis-Driven M2 Macrophage Impairs Fibrotic Encapsulation and Promotes Echinococcus multilocularis Growth in Cotton Rats (Sigmodon hispidus). Microscopy And Microanalysis : The Official Journal Of Microscopy Society Of America, Microbeam Analysis Society, Microscopical Society Of Canada. 2025;31(5) 

Kurahara, Natsume; Yutsudo, Ayami; Yamato, Osamu; Miyoshi, Noriaki; Hifumi, Tatsuro; Yabuki, Akira. Apoptosis in kidney tissue of senior and geriatric cats with chronic kidney disease. The Journal Of Veterinary Medical Science. 2025;87(3):248-256. 

Hayburn, Regina; Chung, Dongjun; Gupta, Arkobato; Sills, Shane; Wu, Jennifer Donglan; Ambrus, Andy; Jing, Weiqing; Ng, Juliana; Penaloza-MacMaster, Pablo; Selmek, Aubrie; Pollack, Seth M; Bracha, Shay. The Immune Landscape of Canine Soft Tissue Sarcomas as a Model for Human Soft Tissue Sarcomas. Cancers. 2025;17(23) 

Asanuma, Kunihiro; Nakatsuka, Atsuhiro; Nakamura, Tomoki; Fujimori, Masashi; Yamanaka, Takashi; Hagi, Tomohito; Matsuyama, Yumi; Iino, Takahiro; Hasegawa, Masahiro. Cryoablation for Malignant Bone and Soft Tissue Tumors and Histological Assessment of Ablated Tumors. Anticancer Research. 2024;44(12):5463-5476. 

Knudsen, Arnon Møldrup; Ewald, Jesper Dupont; Pedersen, Vilde; Haupt-Jorgensen, Martin; Hansen, Elisabeth Victoria Riber; Kristensen, Bjarne Winther. Characterisation of the tumour microenvironment in primary and recurrent glioblastomas. Neuropathology And Applied Neurobiology. 2024;50(5):e13012. 

Agerholm, Jørgen S; Mason, Gary; Steffen, David. Congenital localized cutaneous Langerhans cell histiocytosis in a Holstein calf. Journal Of Veterinary Diagnostic Investigation : Official Publication Of The American Association Of Veterinary Laboratory Diagnosticians, Inc. 2024;36(4):583-585. 

Mathur, Radhika; Wang, Qixuan; Schupp, Patrick G; Nikolic, Ana; Hilz, Stephanie; Hong, Chibo; Grishanina, Nadia R; Kwok, Darwin; Stevers, Nicholas O; Jin, Qiushi; Youngblood, Mark W; Stasiak, Lena Ann; Hou, Ye; Wang, Juan; Yamaguchi, Takafumi N; Lafontaine, Marisa; Shai, Anny; Smirnov, Ivan V; Solomon, David A; Chang, Susan M; Hervey-Jumper, Shawn L; Berger, Mitchel S; Lupo, Janine M; Okada, Hideho; Phillips, Joanna J; Boutros, Paul C; Gallo, Marco; Oldham, Michael C; Yue, Feng; Costello, Joseph F. Glioblastoma evolution and heterogeneity from a 3D whole-tumor perspective. Cell. 2024;187(2):446-463.e16. 

Irie, Tomoaki; Yoshii, Daiki; Komohara, Yoshihiro; Fujiwara, Yukio; Kadohisa, Masashi; Honda, Masaki; Suzu, Shinya; Matsuura, Toshiharu; Kohashi, Kenichi; Oda, Yoshinao; Hibi, Taizo. IL-34 in hepatoblastoma cells potentially promote tumor progression via autocrine and paracrine mechanisms. Cancer Medicine. 2022;11(6):1441-1453. 

Porcellato, Ilaria; Sforna, Monica; Lo Giudice, Adriana; Bossi, Ilaria; Musi, Alice; Tognoloni, Alessia; Chiaradia, Elisabetta; Mechelli, Luca; Brachelente, Chiara. Tumor-Associated Macrophages in Canine Oral and Cutaneous Melanomas and Melanocytomas: Phenotypic and Prognostic Assessment. Frontiers In Veterinary Science. 9:878949. 

Yamane, Taishi; Kanamori, Yohei; Sawayama, Hiroshi; Yano, Hiromu; Nita, Akihiro; Ohta, Yudai; Hinokuma, Hironori; Maeda, Ayato; Iwai, Akiko; Matsumoto, Takashi; Shimoda, Mayuko; Niimura, Mayumi; Usuki, Shingo; Yasuda-Yoshihara, Noriko; Niwa, Masato; Baba, Yoshifumi; Ishimoto, Takatsugu; Komohara, Yoshihiro; Sawa, Tomohiro; Hirayama, Tasuku; Baba, Hideo; Moroishi, Toshiro. Iron accelerates Fusobacterium nucleatum-induced CCL8 expression in macrophages and is associated with colorectal cancer progression. Jci Insight. 2022;7(21) 

Tada, Yoichiro; Matsumi, Yoshiaki; Hara, Kazushi; Miyauchi, Wataru; Sugesawa, Ken; Uejima, Chihiro; Tanio, Akimitsu; Kihara, Kyoichi; Yamamoto, Manabu; Takano, Shuichi; Sakamoto, Teruhisa; Nakayama, Yuji; Hasegawa, Toshimichi; Fujiwara, Yoshiyuki. Infiltration of CD204-overexpressing Macrophages Contributes to the Progression of Stage II and III Colorectal Cancer. Anticancer Research. 2021;41(10):4857-4865. 

Yoshii, Daiki; Nakagawa, Takenobu; Komohara, Yoshihiro; Kawaguchi, Hiroaki; Yamada, Sohsuke; Tanimoto, Akihide. Phenotypic Changes in Macrophage Activation in a Model of Nonalcoholic Fatty Liver Disease using Microminipigs. Journal Of Atherosclerosis And Thrombosis. 2021;28(8):844-851. 

Shima, Toshiyuki; Shimoda, Masayuki; Shigenobu, Takao; Ohtsuka, Takashi; Nishimura, Tomoyasu; Emoto, Katsura; Hayashi, Yuichiro; Iwasaki, Tatsuro; Abe, Takayuki; Asamura, Hisao; Kanai, Yae. Infiltration of tumor-associated macrophages is involved in tumor programmed death-ligand 1 expression in early lung adenocarcinoma. Cancer Science. 2020;111(2):727-738. 

Withers, Sita S; York, Daniel; Choi, Jin W; Woolard, Kevin D; Laufer-Amorim, Renee; Sparger, Ellen E; Burton, Jenna H; McSorley, Stephen J; Monjazeb, Arta M; Murphy, William J; Canter, Robert J; Rebhun, Robert B. Metastatic immune infiltrates correlate with those of the primary tumour in canine osteosarcoma. Veterinary And Comparative Oncology. 2019;17(3):242-252. 

Komohara, Yoshihiro; Kawauchi, Ryuta; Makiyama, Erika; Mikami, Kazuki; Horlad, Hasita; Fujiwara, Yukio; Kida, Tetsuya; Takeya, Motohiro; Niidome, Takuro. Selective depletion of cultured macrophages by magnetite nanoparticles modified with gelatin. Experimental And Therapeutic Medicine. 2017;14(2):1640-1646. 

Golbar, H M; Izawa, Takeshi; Murai, Fumi; Kuwamura, Mitsuru; Yamate, Jyoji. Immunohistochemical analyses of the kinetics and distribution of macrophages, hepatic stellate cells and bile duct epithelia in the developing rat liver. Experimental And Toxicologic Pathology : Official Journal Of The Gesellschaft Fur Toxikologische Pathologie. 2012;64(1-2):1-8. 

Ikezumi, Yohei; Suzuki, Toshiaki; Karasawa, Tamaki; Hasegawa, Hiroya; Yamada, Takeshi; Imai, Naofumi; Narita, Ichiei; Kawachi, Hiroshi; Polkinghorne, Kevan R; Nikolic-Paterson, David J; Uchiyama, Makoto. Identification of alternatively activated macrophages in new-onset paediatric and adult immunoglobulin A nephropathy: potential role in mesangial matrix expansion. Histopathology. 2011;58(2):198-210. 

Higashi-Kuwata, Nobuyo; Jinnin, Masatoshi; Makino, Takamitsu; Fukushima, Satoshi; Inoue, Yuji; Muchemwa, Faith C; Yonemura, Yuji; Komohara, Yoshihiro; Takeya, Motohiro; Mitsuya, Hiroaki; Ihn, Hironobu. Characterization of monocyte/macrophage subsets in the skin and peripheral blood derived from patients with systemic sclerosis. Arthritis Research & Therapy. 12(4):R128. 

Ohnishi, Koji; Komohara, Yoshihiro; Sakashita, Naomi; Iyama, Ken-Ichi; Murayama, Toshihiko; Takeya, Motohiro. Macrophages in Langerhans cell histiocytosis are differentiated toward M2 phenotype: their possible involvement in pathological processes. Pathology International. 2010;60(1):27-34.