Application: WB, IF, IP, ELISA
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Mouse
Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).
Clonality: Monoclonal
Purification: Purified - Affinity
Reactivity: Human, Mouse
Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).
| Documents & Links for Anti ILK mAb (Clone 6A5) | |
| Datasheet | Anti ILK mAb (Clone 6A5) Datasheet |
| Vendor Page | Anti ILK mAb (Clone 6A5) at CUSABIO |
| Documents & Links for Anti ILK mAb (Clone 6A5) | |
| Datasheet | Anti ILK mAb (Clone 6A5) Datasheet |
| Vendor Page | Anti ILK mAb (Clone 6A5) |
