Anti ILK mAb (Clone 6A5)

CUSABIO

SKU: CSB-RA963626A0HU-50

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Receptor-proximal protein kinase regulating integrin-mediated signal transduction (PubMed:8538749, PubMed:9736715). May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B (PubMed:8538749, PubMed:9736715).

Product Specifications

• Application: WB, IF, IP, ELISA
• Reactivity: Human, Mouse
• Clonality: Monoclonal (Clone No.: 6A5)