Anti IFNAR1 mAb (Clone 1B12)

CUSABIO

SKU:
CSB-RA011046A0HU-50
  • Anti IFNAR1 mAb (Clone 1B12)
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Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).

Product Specifications
Application ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 1B12)


Documents & Links for Anti IFNAR1 mAb (Clone 1B12)
Datasheet Anti IFNAR1 mAb (Clone 1B12) Datasheet

Documents & Links for Anti IFNAR1 mAb (Clone 1B12)
Datasheet Anti IFNAR1 mAb (Clone 1B12) Datasheet