Anti HMGCR mAb (Clone CL0260, ATL-AMAb90619 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-AMAb90619-25
  • Immunohistochemistry analysis in human liver and skeletal muscle tissues using AMAb90619 antibody. Corresponding HMGCR RNA-seq data are presented for the same tissues.
  • Western blot analysis in MCF-7 cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-HMGCR antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
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Protein Description: 3-hydroxy-3-methylglutaryl-coa reductase
Gene Name: HMGCR
Alternative Gene Name:
Clone ID: CL0260
Isotype: IgG1
Interspecies mouse/rat: ENSMUSG00000021670: 94%, ENSRNOG00000016122: 92%
Entrez Gene ID: 3156
Uniprot ID: P04035
Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, IHC
Reactivity Human
Clonality Monoclonal IgG1 (Clone No.: CL0260)
Host Mouse
Gene ID - Mouse ENSMUSG00000021670
Gene ID - Rat ENSRNOG00000016122
Buffer The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.



Documents & Links for Anti HMGCR mAb (Clone CL0260, ATL-AMAb90619 w/enhanced validation)
Datasheet Anti HMGCR mAb (Clone CL0260, ATL-AMAb90619 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti HMGCR mAb (Clone CL0260, ATL-AMAb90619 w/enhanced validation)



Citations for Anti HMGCR mAb (Clone CL0260, ATL-AMAb90619 w/enhanced validation) – 2 Found
Kimbung, Siker; Lettiero, Barbara; Feldt, Maria; Bosch, Ana; Borgquist, Signe. High expression of cholesterol biosynthesis genes is associated with resistance to statin treatment and inferior survival in breast cancer. Oncotarget. 2016;7(37):59640-59651.  PubMed
Bjarnadottir, Olöf; Feldt, Maria; Inasu, Maria; Bendahl, Pär-Ola; Elebro, Karin; Kimbung, Siker; Borgquist, Signe. Statin use, HMGCR expression, and breast cancer survival - The Malmö Diet and Cancer Study. Scientific Reports. 2020;10(1):558.  PubMed