Anti HMGCR mAb (Clone CL0259, ATL-AMAb90618 w/enhanced validation)

Atlas Antibodies

SKU: ATL-AMAb90618-25

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Protein Description: 3-hydroxy-3-methylglutaryl-coa reductase
Gene Name: HMGCR
Alternative Gene Name:
Clone ID: CL0259
Isotype: IgG2a
Interspecies mouse/rat: ENSMUSG00000021670: 96%, ENSRNOG00000016122: 96%
Entrez Gene ID: 3156
Uniprot ID: P04035
Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, IHC
• Reactivity: Human
• Clonality: Monoclonal IgG2a (Clone No.: CL0259)
• Host: Mouse
• Gene ID - Mouse: ENSMUSG00000021670
• Gene ID - Rat: ENSRNOG00000016122
• Buffer: The antibodies are delivered in 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti HMGCR mAb (Clone CL0259, ATL-AMAb90618 w/enhanced validation) – 3 Found

Warita, Katsuhiko; Ishikawa, Takuro; Sugiura, Akihiro; Tashiro, Jiro; Shimakura, Hiroaki; Hosaka, Yoshinao Z; Ohta, Ken-Ichi; Warita, Tomoko; Oltvai, Zoltán N. Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells. Scientific Reports. 2021;11(1):12763. 

Bjarnadottir, Olöf; Feldt, Maria; Inasu, Maria; Bendahl, Pär-Ola; Elebro, Karin; Kimbung, Siker; Borgquist, Signe. Statin use, HMGCR expression, and breast cancer survival - The Malmö Diet and Cancer Study. Scientific Reports. 2020;10(1):558. 

Ranea-Robles, Pablo; Chen, Hongjie; Stauffer, Brandon; Yu, Chunli; Bhattacharya, Dipankar; Friedman, Scott L; Puchowicz, Michelle; Houten, Sander M. The peroxisomal transporter ABCD3 plays a major role in hepatic dicarboxylic fatty acid metabolism and lipid homeostasis. Journal Of Inherited Metabolic Disease. 2021;44(6):1419-1433.