Anti Histone H3.1 (HIST1H3A) T32ph mAb (Clone 6C7G12)

Cosmo Bio LTD

Catalog No: CAC-CEC-003

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Application: ICC, WB, ELISA 
Clonality: Monoclonal 
Host: Rat 
Purification: Ion-exchange Chromatography 
Reactivity: Hamster, Monkey, Mouse, Rat, Human 

Background
Post-translation modifications of histones modulate the accessibility and transcriptional competence of specific chromatin regions within the eukaryotic genome. Phosphorylation of histone H3 is unique in the sense that it associates on one hand with open chromatin during gene activation and marks on the other hand highly condensed chromatin during mitosis.



Immunoblot analysis of treated-cell extracts using histone H3 T32ph antibody 6C7G12.

Immunocytochemical analysis of HeLa cells using histone H3 T32ph antibody 6C7G12.

The composition of Histone H3 peptides and the reactivity of histone H3 T32ph antibody 6C7G12.

References
Strahl and Allis. (2000) Nature. 403(6765):41-5. PMID: 10638745.