Anti-Go α (GTP binding protein Go α subunit) pAb

MBL Life Sciences

Product Description

The heterotrimeric guanine nucleotide-binding regulatory proteins (G-proteins) mediate signaling from transmembrane cell surface receptors to a variety of intracellular effectors. G-proteins are composed of a 36-52 kDa α-subunit, a 35-36 kDa β-subunit, and an 8-10 kDa γ-subunit. The αsubunits bind and hydrolyze GTP and are involved in regulation of intracellular effectors. In mammals, G α proteins are encoded by at least 16 genes.

Western Blotting

1. Takigami S et al. Projection pattern of vomeronasal neurons to the accessory olfactory bulb in goats. Chem Senses. 25, 387-393 (2000)(PMID:10944501)
2. Krsmanovic LZ et al. Muscarinic regulation of intracellular signaling and neurosecretion in gonadotropin-releasing hormone neurons. Endocrinology. 139, 4037-4043 (1998)(PMID:9751480)
3. Kato K et al. Production of the alpha subunit of guanine nucleotide-binding protein GO by neuroendocrine tumors. Cancer Res. 47, 5800-5805 (1987)(PMID:2822234)
4. Takigami S et al. Morphological evidence for two types of Mammalian vomeronasal system. Chem Senses. 29, 301-310 (2004)(PMID:15150143)

Immunohistochemistry

1. Takigami S et al. Projection pattern of vomeronasal neurons to the accessory olfactory bulb in goats. Chem Senses. 25, 387-393 (2000)(PMID:10944501)
2. Matsuoka M et al. Immunocytochemical study of G(i)2alpha and G(o)alpha on the epithelium surface of the rat vomeronasal organ. Chem Senses. 26, 161-166 (2001)(PMID:11238246)
3. Kato K et al. Production of the alpha subunit of guanine nucleotide-binding protein GO by neuroendocrine tumors. Cancer Res. 47, 5800-5805 (1987)(PMID:2822234)
4. Takigami S et al. Morphological evidence for two types of Mammalian vomeronasal system. Chem Senses. 29, 301-310 (2004)(PMID:15150143)
5. Prince JE et al. Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 29,14211-14222 (2009)(PMID:19906969)

Product Specifications

• Application: WB, IP, IH
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: Bovine Go α