Anti GCLC pAb (ATL-HPA036359 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA036359-25
  • Immunohistochemical staining of human esophagus shows strong cytoplasmic positivity in squamous epithelial cells.
  • Western blot analysis in human cell lines A-549 and U-251MG using Anti-GCLC antibody. Corresponding GCLC RNA-seq data are presented for the same cell lines. Loading control: Anti-HDAC1.
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Protein Description: glutamate-cysteine ligase, catalytic subunit
Gene Name: GCLC
Alternative Gene Name: GCS, GLCL, GLCLC
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000032350: 94%, ENSRNOG00000006302: 95%
Entrez Gene ID: 2729
Uniprot ID: P48506
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application WB, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen DEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFTEDDEASRASKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLAT
Gene Sequence DEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFTEDDEASRASKPDHIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLAT
Gene ID - Mouse ENSMUSG00000032350
Gene ID - Rat ENSRNOG00000006302
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti GCLC pAb (ATL-HPA036359 w/enhanced validation)
Datasheet Anti GCLC pAb (ATL-HPA036359 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti GCLC pAb (ATL-HPA036359 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti GCLC pAb (ATL-HPA036359 w/enhanced validation)
Datasheet Anti GCLC pAb (ATL-HPA036359 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti GCLC pAb (ATL-HPA036359 w/enhanced validation)



Citations for Anti GCLC pAb (ATL-HPA036359 w/enhanced validation) – 1 Found
Wang, Gary X; Tu, Ho-Chou; Dong, Yiyu; Skanderup, Anders Jacobsen; Wang, Yufeng; Takeda, Shugaku; Ganesan, Yogesh Tengarai; Han, Song; Liu, Han; Hsieh, James J; Cheng, Emily H. ΔNp63 Inhibits Oxidative Stress-Induced Cell Death, Including Ferroptosis, and Cooperates with the BCL-2 Family to Promote Clonogenic Survival. Cell Reports. 2017;21(10):2926-2939.  PubMed