Immunofluorescence analysis of monoclonal antibody (E39) recognition of gamma-tubulin at centrosomes. Gamma-tubulin in normal or cancer cells was stained by immunofluorescence described below. The presence of supernumerary centrosomes is a common event in human tumors. Yellow and blue indicate gamma-tubulin and nuclear DNA, respectively. A: normal human fibroblasts. B: colon cancer cell line (CaCo-2). C: fibrosarcoma cell line (HT-1080).

Anti Tubulin Gamma-1 Chain (GCP-1) mAb (Clone E39)

Catalog No:
CAC-NM-MA-003
$419.00

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Application: ICC, ELISA, WB, IF 
Clonality: Monoclonal 
Host: Mouse 
Purification: Ammonium Sulfate 
Reactivity: Human, Mouse, Rat 

Gamma-tubulins constitute a ubiquitous and highly conserved subfamily of the tubulin family. The protein is found at microtubule-organizing centers, such as spindle poles or centrosomes. It remains associated with centrosomes when microtubules are depolymerized, suggesting that it is an integral component that may play a role in minus-end nucleation of microtubule assembly. Thus, gamma-tubulins can be used as a centrosome maker.

Documents & Links for Anti Tubulin Gamma-1 Chain (GCP-1) mAb (Clone E39)
Datasheet cac-nm-ma-003_anti-gamma-tubulin-mab-clone-e39_datasheet.pdf

Documents & Links for Anti Tubulin Gamma-1 Chain (GCP-1) mAb (Clone E39)
Datasheet cac-nm-ma-003_anti-gamma-tubulin-mab-clone-e39_datasheet.pdf