Anti FBP1 mAb (Clone 4G3)

CUSABIO

SKU: CSB-RA787345A0HU-50

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Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Product Specifications

• Application: IHC, ELISA
• Reactivity: Human
• Clonality: Monoclonal (Clone No.: 4G3)