Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation)

Atlas Antibodies

SKU:
ATL-HPA021057-25
  • Immunohistochemistry analysis in human cervix, uterine and cerebral cortex tissues using HPA021057 antibody. Corresponding FBN1 RNA-seq data are presented for the same tissues.
  • Immunofluorescent staining of human cell line U-251 MG shows localization to cytosol.
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Protein Description: fibrillin 1
Gene Name: FBN1
Alternative Gene Name: FBN, MASS, MFS1, OCTD, SGS, WMS
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000027204: 89%, ENSRNOG00000007302: 89%
Entrez Gene ID: 2200
Uniprot ID: P35555
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications
Application ICC, IHC
Reactivity Human
Clonality Polyclonal
Host Rabbit
Immunogen DVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCEC
Gene Sequence DVRPGYCYTALTNGRCSNQLPQSITKMQCCCDAGRCWSPGVTVAPEMCPIRATEDFNKLCSVPMVIPGRPEYPPPPLGPIPPVLPVPPGFPPGPQIPVPRPPVEYLYPSREPPRVLPVNVTDYCQLVRYLCQNGRCIPTPGSCRCEC
Gene ID - Mouse ENSMUSG00000027204
Gene ID - Rat ENSRNOG00000007302
Buffer 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.


Documents & Links for Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation)
Datasheet Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation) at Atlas Antibodies

Documents & Links for Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation)
Datasheet Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation) Datasheet (External Link)
Vendor Page Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation)



Citations for Anti FBN1 pAb (ATL-HPA021057 w/enhanced validation) – 6 Found
Edlund, Karolina; Lindskog, Cecilia; Saito, Akira; Berglund, Anders; Pontén, Fredrik; Göransson-Kultima, Hanna; Isaksson, Anders; Jirström, Karin; Planck, Maria; Johansson, Leif; Lambe, Mats; Holmberg, Lars; Nyberg, Fredrik; Ekman, Simon; Bergqvist, Michael; Landelius, Per; Lamberg, Kristina; Botling, Johan; Ostman, Arne; Micke, Patrick. CD99 is a novel prognostic stromal marker in non-small cell lung cancer. International Journal Of Cancer. 2012;131(10):2264-73.  PubMed
Zhang, Wei; Ota, Takayo; Shridhar, Viji; Chien, Jeremy; Wu, Baolin; Kuang, Rui. Network-based survival analysis reveals subnetwork signatures for predicting outcomes of ovarian cancer treatment. Plos Computational Biology. 9(3):e1002975.  PubMed
Baldwin, Andrew K; Cain, Stuart A; Lennon, Rachel; Godwin, Alan; Merry, Catherine L R; Kielty, Cay M. Epithelial-mesenchymal status influences how cells deposit fibrillin microfibrils. Journal Of Cell Science. 2014;127(Pt 1):158-71.  PubMed
Cain, Stuart A; Mularczyk, Ewa J; Singh, Mukti; Massam-Wu, Teresa; Kielty, Cay M. ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions. Scientific Reports. 2016;6( 27779234):35956.  PubMed
Asgari, Samira; Luo, Yang; Akbari, Ali; Belbin, Gillian M; Li, Xinyi; Harris, Daniel N; Selig, Martin; Bartell, Eric; Calderon, Roger; Slowikowski, Kamil; Contreras, Carmen; Yataco, Rosa; Galea, Jerome T; Jimenez, Judith; Coit, Julia M; Farroñay, Chandel; Nazarian, Rosalynn M; O'Connor, Timothy D; Dietz, Harry C; Hirschhorn, Joel N; Guio, Heinner; Lecca, Leonid; Kenny, Eimear E; Freeman, Esther E; Murray, Megan B; Raychaudhuri, Soumya. A positively selected FBN1 missense variant reduces height in Peruvian individuals. Nature. 2020;582(7811):234-239.  PubMed
Matsuzaki, Tomoko; Keene, Douglas R; Nishimoto, Emi; Noda, Makoto. Reversion-inducing cysteine-rich protein with Kazal motifs and MT1-MMP promote the formation of robust fibrillin fibers. Journal Of Cellular Physiology. 2021;236(3):1980-1995.  PubMed