Anti FAT1 pAb (ATL-HPA023882)

Atlas Antibodies

SKU: ATL-HPA023882-25

• 

Protein Description: FAT atypical cadherin 1
Gene Name: FAT1
Alternative Gene Name: CDHF7, CDHR8, FAT
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000070047: 88%, ENSRNOG00000030954: 90%
Entrez Gene ID: 2195
Uniprot ID: Q14517
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: NFQRALRNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAGLDCPWKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVCLCKEGRCP
• Gene Sequence: NFQRALRNILGVRRNDIQIVSLQSSEPHPHLDVLLFVEKPGSAQISTKQLLHKINSSVTDIEEIIGVRILNVFQKLCAGLDCPWKFCDEKVSVDESVMSTHSTARLSFVTPRHHRAAVCLCKEGRCP
• Gene ID - Mouse: ENSMUSG00000070047
• Gene ID - Rat: ENSRNOG00000030954
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti FAT1 pAb (ATL-HPA023882) – 8 Found

Hu, Xiaoling; Zhai, Yuanfang; Shi, Ruyi; Qian, Yu; Cui, Heyang; Yang, Jie; Bi, Yanghui; Yan, Ting; Yang, Jian; Ma, Yanchun; Zhang, Ling; Liu, Yiqian; Li, Guodong; Zhang, Mingsheng; Cui, Yongping; Kong, Pengzhou; Cheng, Xiaolong. FAT1 inhibits cell migration and invasion by affecting cellular mechanical properties in esophageal squamous cell carcinoma. Oncology Reports. 2018;39(5):2136-2146. 

Morris, Luc G T; Kaufman, Andrew M; Gong, Yongxing; Ramaswami, Deepa; Walsh, Logan A; Turcan, Şevin; Eng, Stephanie; Kannan, Kasthuri; Zou, Yilong; Peng, Luke; Banuchi, Victoria E; Paty, Phillip; Zeng, Zhaoshi; Vakiani, Efsevia; Solit, David; Singh, Bhuvanesh; Ganly, Ian; Liau, Linda; Cloughesy, Timothy C; Mischel, Paul S; Mellinghoff, Ingo K; Chan, Timothy A. Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation. Nature Genetics. 2013;45(3):253-61. 

Caruso, Nathalie; Herberth, Balàzs; Bartoli, Marc; Puppo, Francesca; Dumonceaux, Julie; Zimmermann, Angela; Denadai, Simon; Lebossé, Marie; Roche, Stephane; Geng, Linda; Magdinier, Frederique; Attarian, Shahram; Bernard, Rafaelle; Maina, Flavio; Levy, Nicolas; Helmbacher, Françoise. Deregulation of the protocadherin gene FAT1 alters muscle shapes: implications for the pathogenesis of facioscapulohumeral dystrophy. Plos Genetics. 2013;9(6):e1003550. 

Wojtalewicz, Nathalie; Sadeqzadeh, Elham; Weiß, Jakob V; Tehrani, Mahnaz Moradian; Klein-Scory, Susanne; Hahn, Stephan; Schmiegel, Wolff; Warnken, Uwe; Schnölzer, Martina; de Bock, Charles E; Thorne, Rick F; Schwarte-Waldhoff, Irmgard. A soluble form of the giant cadherin Fat1 is released from pancreatic cancer cells by ADAM10 mediated ectodomain shedding. Plos One. 9(3):e90461. 

Lin, De-Chen; Hao, Jia-Jie; Nagata, Yasunobu; Xu, Liang; Shang, Li; Meng, Xuan; Sato, Yusuke; Okuno, Yusuke; Varela, Ana Maria; Ding, Ling-Wen; Garg, Manoj; Liu, Li-Zhen; Yang, Henry; Yin, Dong; Shi, Zhi-Zhou; Jiang, Yan-Yi; Gu, Wen-Yue; Gong, Ting; Zhang, Yu; Xu, Xin; Kalid, Ori; Shacham, Sharon; Ogawa, Seishi; Wang, Ming-Rong; Koeffler, H Phillip. Genomic and molecular characterization of esophageal squamous cell carcinoma. Nature Genetics. 2014;46(5):467-73. 

Weekes, Michael P; Tomasec, Peter; Huttlin, Edward L; Fielding, Ceri A; Nusinow, David; Stanton, Richard J; Wang, Eddie C Y; Aicheler, Rebecca; Murrell, Isa; Wilkinson, Gavin W G; Lehner, Paul J; Gygi, Steven P. Quantitative temporal viromics: an approach to investigate host-pathogen interaction. Cell. 2014;157(6):1460-1472. 

Lin, De-Chen; Meng, Xuan; Hazawa, Masaharu; Nagata, Yasunobu; Varela, Ana Maria; Xu, Liang; Sato, Yusuke; Liu, Li-Zhen; Ding, Ling-Wen; Sharma, Arjun; Goh, Boon Cher; Lee, Soo Chin; Petersson, Bengt Fredrik; Yu, Feng Gang; Macary, Paul; Oo, Min Zin; Ha, Chan Soh; Yang, Henry; Ogawa, Seishi; Loh, Kwok Seng; Koeffler, H Phillip. The genomic landscape of nasopharyngeal carcinoma. Nature Genetics. 2014;46(8):866-71. 

Meng, Panpan; Zhang, Yi-Fan; Zhang, Wangli; Chen, Xin; Xu, Tong; Hu, Sheng; Liang, Xinjun; Feng, Mingqian; Yang, Xiaoqing; Ho, Mitchell. Identification of the atypical cadherin FAT1 as a novel glypican-3 interacting protein in liver cancer cells. Scientific Reports. 2021;11(1):40.