Anti FAM208A pAb (ATL-HPA006735)

Atlas Antibodies

SKU: ATL-HPA006735-25

• 

Protein Description: family with sequence similarity 208, member A
Gene Name: FAM208A
Alternative Gene Name: C3orf63, KIAA1105, RAP140, se89-1
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000040651: 63%, ENSRNOG00000014750: 66%
Entrez Gene ID: 23272
Uniprot ID: Q9UK61
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: TIIIKASAKGGNLPPVSPNDSGAKIASNPLERHVIPVSSSDFNNKHLLEPLCSDPLKDTNSDEQHSTSALTEVEMNQPQHATELMVTSDHIVPGDMAREPVEETTKSPSDVNISAQPALSN
• Gene Sequence: TIIIKASAKGGNLPPVSPNDSGAKIASNPLERHVIPVSSSDFNNKHLLEPLCSDPLKDTNSDEQHSTSALTEVEMNQPQHATELMVTSDHIVPGDMAREPVEETTKSPSDVNISAQPALSN
• Gene ID - Mouse: ENSMUSG00000040651
• Gene ID - Rat: ENSRNOG00000014750
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti FAM208A pAb (ATL-HPA006735) – 14 Found

Tchasovnikarova, Iva A; Timms, Richard T; Matheson, Nicholas J; Wals, Kim; Antrobus, Robin; Göttgens, Berthold; Dougan, Gordon; Dawson, Mark A; Lehner, Paul J. GENE SILENCING. Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells. Science (New York, N.y.). 2015;348(6242):1481-1485. 

Tchasovnikarova, Iva A; Timms, Richard T; Douse, Christopher H; Roberts, Rhys C; Dougan, Gordon; Kingston, Robert E; Modis, Yorgo; Lehner, Paul J. Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2. Nature Genetics. 2017;49(7):1035-1044. 

Liu, Nian; Lee, Cameron H; Swigut, Tomek; Grow, Edward; Gu, Bo; Bassik, Michael C; Wysocka, Joanna. Selective silencing of euchromatic L1s revealed by genome-wide screens for L1 regulators. Nature. 2018;553(7687):228-232. 

Yan, Junpeng; Shun, Ming-Chieh; Zhang, Yi; Hao, Caili; Skowronski, Jacek. HIV-1 Vpr counteracts HLTF-mediated restriction of HIV-1 infection in T cells. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2019;116(19):9568-9577. 

Greenwood, Edward J D; Williamson, James C; Sienkiewicz, Agata; Naamati, Adi; Matheson, Nicholas J; Lehner, Paul J. Promiscuous Targeting of Cellular Proteins by Vpr Drives Systems-Level Proteomic Remodeling in HIV-1 Infection. Cell Reports. 2019;27(5):1579-1596.e7. 

Martin, Michaël M; Matkovic, Roy; Larrous, Pauline; Morel, Marina; Lasserre, Angélique; Vauthier, Virginie; Margottin-Goguet, Florence. Binding to DCAF1 distinguishes TASOR and SAMHD1 degradation by HIV-2 Vpx. Plos Pathogens. 2021;17(10):e1009609. 

Seczynska, Marta; Bloor, Stuart; Cuesta, Sergio Martinez; Lehner, Paul J. Genome surveillance by HUSH-mediated silencing of intronless mobile elements. Nature. 2022;601(7893):440-445. 

Das, Anshuman; Vijayan, Madhuvanthi; Walton, Eric M; Stafford, V Grace; Fiflis, David N; Asokan, Aravind. Epigenetic Silencing of Recombinant Adeno-associated Virus Genomes by NP220 and the HUSH Complex. Journal Of Virology. 2022;96(4):e0203921. 

Zhang, Fang; Santilli, Giorgia; Thrasher, Adrian J. Characterization of a core region in the A2UCOE that confers effective anti-silencing activity. Scientific Reports. 2017;7(1):10213. 

Prigozhin, Daniil M; Douse, Christopher H; Farleigh, Laura E; Albecka, Anna; Tchasovnikarova, Iva A; Timms, Richard T; Oda, Shun-Ichiro; Adolf, Frank; Freund, Stefan M V; Maslen, Sarah; Lehner, Paul J; Modis, Yorgo. Periphilin self-association underpins epigenetic silencing by the HUSH complex. Nucleic Acids Research. 2020;48(18):10313-10328. 

Douse, Christopher H; Tchasovnikarova, Iva A; Timms, Richard T; Protasio, Anna V; Seczynska, Marta; Prigozhin, Daniil M; Albecka, Anna; Wagstaff, Jane; Williamson, James C; Freund, Stefan M V; Lehner, Paul J; Modis, Yorgo. TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control. Nature Communications. 2020;11(1):4940. 

Waybright, Jarod M; Clinkscales, Sarah E; Barnash, Kimberly D; Budziszewski, Gabrielle R; Rectenwald, Justin M; Chiarella, Anna M; Norris-Drouin, Jacqueline L; Cholensky, Stephanie H; Pearce, Kenneth H; Herring, Laura E; McGinty, Robert K; Hathaway, Nathaniel A; James, Lindsey I. A Peptidomimetic Ligand Targeting the Chromodomain of MPP8 Reveals HRP2's Association with the HUSH Complex. Acs Chemical Biology. 2021;16(9):1721-1736. 

Vauthier, Virginie; Lasserre, Angélique; Morel, Marina; Versapuech, Margaux; Berlioz-Torrent, Clarisse; Zamborlini, Alessia; Margottin-Goguet, Florence; Matkovic, Roy. HUSH-mediated HIV silencing is independent of TASOR phosphorylation on threonine 819. Retrovirology. 2022;19(1):23. 

Wistner, Sarah C; MacDonald, Ian A; Stanley, Karly A; Hathaway, Nathaniel A. Characterization of Hepatoma-Derived Growth Factor-Related Protein 2 Interactions with Heterochromatin. Cells. 2023;12(2)