Anti FAAP20 pAb (ATL-HPA038829)

Atlas Antibodies

SKU: ATL-HPA038829-25

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Protein Description: Fanconi anemia core complex associated protein 20
Gene Name: FAAP20
Alternative Gene Name: C1orf86, FLJ31031
Isotype: IgG
Interspecies mouse/rat: ENSMUSG00000073684: 58%, ENSRNOG00000036876: 55%
Entrez Gene ID: 199990
Uniprot ID: Q6NZ36
Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.
Storage Temperature: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Product Specifications

• Application: WB, ICC, IHC
• Reactivity: Human
• Clonality: Polyclonal
• Host: Rabbit
• Immunogen: GGHLESPARSLPQRPAPDPCRAPRVEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW
• Gene Sequence: GGHLESPARSLPQRPAPDPCRAPRVEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW
• Gene ID - Mouse: ENSMUSG00000073684
• Gene ID - Rat: ENSRNOG00000036876
• Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative.

Citations for Anti FAAP20 pAb (ATL-HPA038829) – 4 Found

Zhang, Tingting; Wilson, Andrew F; Mahmood Ali, Abdullah; Namekawa, Satoshi H; Andreassen, Paul R; Ruhikanta Meetei, Amom; Pang, Qishen. Loss of Faap20 Causes Hematopoietic Stem and Progenitor Cell Depletion in Mice Under Genotoxic Stress. Stem Cells (Dayton, Ohio). 2015;33(7):2320-30. 

Wang, Jingming; Chan, Bryan; Tong, Michael; Paung, YiTing; Jo, Ukhyun; Martin, Dwight; Seeliger, Markus; Haley, John; Kim, Hyungjin. Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway. Plos Genetics. 2019;15(2):e1007983. 

Nagareddy, Bhavika; Khan, Arafat; Kim, Hyungjin. Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation. The Journal Of Biological Chemistry. 2020;295(40):13887-13901. 

Leung, Justin Wai Chung; Wang, Yucai; Fong, Ka Wing; Huen, Michael Shing Yan; Li, Lei; Chen, Junjie. Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proceedings Of The National Academy Of Sciences Of The United States Of America. 2012;109(12):4491-6.