Anti CYP1A2 mAb (Clone 8B2)

CUSABIO

Catalog No.:
CSB-RA178519A0HU-50
Western Blot<br /> Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, L02 whole cell lysate<br /> All lanes: CYP1A2 antibody at 1:1000<br /> Secondary<br /> Goat polyclonal to rabbit IgG at 1/50000 dilution<br /> Predicted band size: 59 kDa<br /> Observed band size: 59 kDa<br />
IHC image of CSB-RA178519A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.
Shipping:
Calculated at Checkout
$221.00
Adding to cart… The item has been added
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.

Product Specifications
Application WB, IHC, ELISA
Reactivity Human
Clonality Monoclonal (Clone No.: 8B2)

Documents & Links for Anti CYP1A2 mAb (Clone 8B2)
Datasheet Anti CYP1A2 mAb (Clone 8B2) Datasheet

Documents & Links for Anti CYP1A2 mAb (Clone 8B2)
Datasheet Anti CYP1A2 mAb (Clone 8B2) Datasheet
!